Invitrogen

Adenosine Deaminase Monoclonal Antibody (12)

查看其他27个ADA抗体

产品信息

MA5-30042

应用

建议稀释比

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酶联免疫吸附实验 (ELISA)

1:1,000-1:2,000

-

产品规格

种属反应

Human

宿主/亚型

Mouse / IgG1

分类

Monoclonal

类型

Antibody

克隆号

12

抗原

Recombinant Human ADA/Adenosine deaminase Protein (Met1-Leu363)

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偶联物

Unconjugated Unconjugated Unconjugated

形式

Liquid

浓度

1 mg/mL

纯化类型

Protein A

保存液

PBS

内含物

no preservative

保存条件

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

运输条件

Ambient (domestic); Wet ice (international)

RRID

AB_2785833

产品详细信息

This product is preservative free. It is recommended to add sodium azide to avoid contamination (final concentration 0.05%-0.1%).

This antibody has specificity for Human ADA/Adenosine deaminase.

靶标信息

Catalyzes the hydrolytic deamination of adenosine and 2-deoxyadenosine. Plays an important role in purine metabolism and in adenosine homeostasis. Modulates signaling by extracellular adenosine, and so contributes indirectly to cellular signaling events. May act as a positive regulator of T-cell coactivation.

仅用于科研。不用于诊断过程。未经明确授权不得转售。

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引用该产品

生物信息学

蛋白别名: Adenosine aminohydrolase; Adenosine deaminase; RP11-61L14.5

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基因别名: ADA; ADA1

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UniProt ID: (Human) P00813

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Entrez Gene ID: (Human) 100

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purine nucleoside binding adenosine deaminase activity protein binding zinc ion binding deaminase

参与通路

response to hypoxia histamine secretion trophectodermal cell differentiation liver development placenta development germinal center B cell differentiation positive regulation of germinal center formation negative regulation of leukocyte migration negative regulation of mature B cell apoptotic process adenosine catabolic process deoxyadenosine catabolic process aging purine ribonucleoside monophosphate biosynthetic process positive regulation of heart rate positive regulation of B cell proliferation purine nucleotide salvage positive regulation of T cell differentiation in thymus response to vitamin E regulation of cell-cell adhesion mediated by integrin T cell activation negative regulation of circadian sleep/wake cycle, non-REM sleep response to drug response to hydrogen peroxide purine-containing compound salvage hypoxanthine salvage response to morphine positive regulation of smooth muscle contraction dATP catabolic process inosine biosynthetic process xanthine biosynthetic process positive regulation of alpha-beta T cell differentiation lung alveolus development Peyer's patch development embryonic digestive tract development negative regulation of inflammatory response positive regulation of calcium-mediated signaling positive regulation of T cell receptor signaling pathway negative regulation of adenosine receptor signaling pathway negative regulation of penile erection negative regulation of thymocyte apoptotic process negative regulation of mucus secretion