Invitrogen

AgRP Polyclonal Antibody

AgRP Antibody in Immunohistochemistry (Paraffin) (IHC (P))

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AgRP Antibody (PA5-47895) in IHC (P)

Immunohistochemical analysis of AgRP in immersion fixed paraffin-embedded sections of human brain (hippocampus). Samples were incubated in AgRP polyclonal antibody (Product # PA5-47895) using a dilution of 15 µg/mL overnight at 4 °C. Before incubation with the primary antibody tissue was subjected to heat-induced epitope retrieval using Antigen Retrieval Reagent-Basic . Tissue was stained using the Anti-Goa... View More

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产品信息

PA5-47895

应用

建议稀释比

已发表文章

免疫印迹 (WB)

0.1 µg/mL

免疫组化（石蜡） (IHC (P))

5-15 µg/mL

产品规格

种属反应

Human

宿主/亚型

Goat / IgG

分类

Polyclonal

类型

Antibody

抗原

Sf 21-derived recombinant human AgRP/ART Ala21-Thr132

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偶联物

Unconjugated Unconjugated Unconjugated

形式

Lyophilized

浓度

0.2 mg/mL

纯化类型

Antigen affinity chromatography

保存液

PBS with 5% trehalose

内含物

No Preservative

保存条件

-20° C, Avoid Freeze/Thaw Cycles

运输条件

Ambient (domestic); Wet ice (international)

RRID

AB_2610536

产品详细信息

In Western blots, approximately 40% cross-reactivity with recombinant mouse AgRP/ART is observed.

Reconstitute at 0.2 mg/mL in sterile PBS.

靶标信息

Agouti-related protein (AgRP), also called agouti-related peptide, is a neuropeptide produced in the brain by the AgRP/NPY neuron. In humans, the agouti-related peptide is encoded by the AGRP gene. This gene encodes an antagonist of the melanocortin-3 and melanocortin-4 receptor. It appears to regulate hypothalamic control of feeding behavior via melanocortin receptor and/or intracellular calcium regulation, and thus plays a role in weight homeostasis. Mutations in this gene have been associated with late on-set obesity.

仅用于科研。不用于诊断过程。未经明确授权不得转售。