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Alcohol Dehydrogenase 1A Antibody (PA5-78730) in ICC/IF
Immunocytochemistry analysis of ADH1A using anti-ADH1A antibody (Product # PA5-78730) . ADH1A was detected in a section of U2OS cells. Enzyme antigen retrieval was performed using IHC enzyme antigen retrieval reagent for 15 mins. The cells were blocked with 10% goat serum and then incubated with 5 μg/mL rabbit anti-ADH1A antibody (Product # PA5-78730) overnight at 4°C. DyLight®488 Conjugated Goat Anti-Rabbi... View More
产品信息
PA5-78730
应用
建议稀释比
已发表文章
产品规格
种属反应
Human,
Mouse,
Rat
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
E. coli-derived human ADH1A recombinant protein (Position: K213-F375).
偶联物
形式
Lyophilized
浓度
500 µg/mL
纯化类型
Antigen affinity chromatography
保存液
PBS with 4mg trehalose
内含物
no preservative
保存条件
-20°C
运输条件
Ambient (domestic); Wet ice (international)
RRID
AB_2745846
产品详细信息
Reconstitute with 0.2 mL of distilled water to yield a concentration of 500 µg/mL.
靶标信息
This gene encodes a member of the alcohol dehydrogenase family. The encoded protein is the alpha subunit of class I alcohol dehydrogenase, which consists of several homo- and heterodimers of alpha, beta and gamma subunits. Alcohol dehydrogenases catalyze the oxidation of alcohols to aldehydes. This gene is active in the liver in early fetal life but only weakly active in adult liver. This gene is found in a cluster with six additional alcohol dehydrogenase genes, including those encoding the beta and gamma subunits, on the long arm of chromosome 4. Mutations in this gene may contribute to variation in certain personality traits and substance dependence.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: ADH, alpha subunit; ADH-A2; Alcohol dehydrogenase 1; alcohol dehydrogenase 1 (class I), alpha polypeptide; alcohol dehydrogenase 1 temporal, liver; alcohol dehydrogenase 1, complex; alcohol dehydrogenase 1, electrophoretic; Alcohol dehydrogenase 1A; alcohol dehydrogenase 3, electrophoretic; Alcohol dehydrogenase A subunit; Alcohol dehydrogenase subunit alpha; aldehyde reductase; class I alcohol dehydrogenase
基因别名: Adh; Adh-1; Adh-1-t; Adh-1e; Adh-1t; Adh-3e; ADH-AA; ADH1; Adh1-e; Adh1-t; ADH1A; Adh1c; Adh1tl; Adh3-e; AI194826
UniProt ID: (Human) P07327, (Mouse) P00329, (Rat) P06757
Entrez Gene ID: (Human) 124, (Mouse) 11522, (Rat) 24172
alcohol dehydrogenase (NAD) activity
alcohol dehydrogenase activity, zinc-dependent
retinol dehydrogenase activity
protein binding
zinc ion binding
drug binding
oxidoreductase activity
ethanol binding
protein homodimerization activity
metal ion binding
NAD binding
dehydrogenase
oxidoreductase
metabolite interconversion enzyme
alcohol metabolic process
ethanol oxidation
drug metabolic process
retinoid metabolic process
ethanol catabolic process
response to retinoic acid
response to testosterone
retinol metabolic process
retinoic acid metabolic process
acetaldehyde biosynthetic process
behavioral response to ethanol
response to steroid hormone
oxidation-reduction process
