Invitrogen

Aldolase A/B/C Monoclonal Antibody (E9)

Aldolase A/B/C Antibody in Immunocytochemistry (ICC/IF)

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Aldolase A/B/C Antibody (MA5-47476) in ICC/IF

Immunocytochemistry analysis of Aldolase C in mixed neuron/glial cultures. Samples were stained with Aldolase C monoclonal antibody (Product # MA5-47476) in red. Costained with chicken antibody to GFAP antibody (green). The aldolase C antibody reveals strong cytoplasmic staining in a subset of non-neuronal cells and apparently all astrocyte cell body and processes, whereas GFAP labels the intermediate filam... View More

Aldolase A/B/C Antibody in Western Blot (WB)

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产品信息

MA5-47476

应用

建议稀释比

已发表文章

免疫印迹 (WB)

1:10,000

免疫组化 (IHC)

1:1,000-1:5,000

免疫细胞化学 (ICC/IF)

1:1,000-1:5,000

产品规格

种属反应

Human, Mouse, Rat

宿主/亚型

Mouse / IgG1

分类

Monoclonal

类型

Antibody

克隆号

抗原

Recombinant human full-length aldolase C

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偶联物

Unconjugated Unconjugated Unconjugated

形式

Liquid

浓度

1 mg/mL

纯化类型

Protein A/G

保存液

PBS with 50% glycerol

内含物

5mM sodium azide

保存条件

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

运输条件

Wet ice

RRID

AB_2942458

靶标信息

Aldolases are important glycolytic cytosolic enzymes which catalyse the reversible conversion of fructose-1,6-bisphosphate to glyceraldehyde 3-phosphate. There are three aldolase isozymes coded by three distinct genes in mammals, namely aldolases A, B, and C. Aldolase A is heavily expressed in muscle enzyme and aldolase B is heavily expressed in liver and is regarded as a liver specific enzyme. In the adult, aldolase C is the brain-specific isozyme expressed in astrocytes and a few classes of neurons, notably Purkinje cells. Appropriate antibodies to aldolase C are therefore useful to identify astrocytes in cell culture and sectioned material, and the enzyme may be over expressed in some forms of cancer.

仅用于科研。不用于诊断过程。未经明确授权不得转售。

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引用该产品

生物信息学

蛋白别名: ALDA; ALDB; ALDC; Aldolase 1; aldolase 1, A isoform; Aldolase 2; aldolase 2, B isoform; Aldolase 3; aldolase A, fructose-bisphosphate; Aldolase B fructose-biphosphate; Aldolase B, fructose-biphosphate; aldolase B, fructose-bisphosphatase; aldolase B, fructose-bisphosphate; aldolase C, fructose-biphosphate; aldolase C, fructose-bisphosphate; Brain-type aldolase; epididymis secretory sperm binding protein Li 87p; fructoaldolase C; fructose-1,6-biphosphate triosephosphate lyase; fructose-1,6-bisphosphate triosephosphate-lyase; Fructose-bisphosphate aldolase A; Fructose-bisphosphate aldolase B; Fructose-bisphosphate aldolase C; Liver-type aldolase; Lung cancer antigen NY-LU-1; Muscle-type aldolase; Scrapie-responsive protein 2; Zebrin II

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基因别名: AI847350; ALDA; ALDB; ALDC; ALDCAA; Aldo-1; Aldo-2; Aldo1; ALDO2; Aldo3; ALDOA; ALDOB; ALDOC; AU040929; BC016435; F16dip7; GSD12; HEL-S-87p; LIV10; RATALDCAA; RNALDOG5; Scrg2