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Alpha-Adducin Antibody (A303-714A-T) in WB
Detection of human Alpha-Adducin by western blot. Samples: Whole cell lysate (50 µg) from HeLa, 293T, and Jurkat cells prepared using NETN lysis buffer. Antibody: Affinity purified rabbit anti-Alpha-Adducin antibody A303-714A-M (lot A303-714A-M-1) used for WB at 1:1000. Detection: Chemiluminescence with an exposure time of 3 seconds.
产品信息
A303-714A-T
产品规格
种属反应
Human
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
Between 632 and 682
偶联物
形式
Liquid
浓度
1 mg/mL
纯化类型
Antigen affinity chromatography
保存液
TBS, pH 7.0 to 8.0
内含物
0.09% sodium azide
保存条件
4° C
运输条件
Wet ice
产品详细信息
The recommended shelf life for this product is 1 year from date of receipt.
Application Note: For IHC, epitope retrieval with citrate buffer pH 6.0 is recommended for FFPE tissue sections.
Based on 100% sequence identity, this antibody is predicted to react with Orangutan
靶标信息
Adducins are a family of cytoskeleton proteins encoded by three genes (alpha, beta, gamma). Adducin is a heterodimeric protein that consists of related subunits, which are produced from distinct genes but share a similar structure. Alpha- and beta-adducin include a protease-resistant N-terminal region and a protease-sensitive, hydrophilic C-terminal region. Alpha- and gamma-adducins are ubiquitously expressed. In contrast, beta-adducin is expressed at high levels in brain and hematopoietic tissues. Adducin binds with high affinity to Ca(2+)/calmodulin and is a substrate for protein kinases A and C. Alternative splicing results in multiple variants encoding distinct isoforms; however, not all variants have been fully described.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: ADD2; ADDB; adducin 1 (alpha); Adducin beta; Adducin-1; Adducin-alpha; Adducin-beta; Adducin1; Alpha adducin; Alpha-adducin; beta Adducin; erythrocyte adducin alpha subunit; Erythrocyte adducin subunit alpha
基因别名: ADD1; ADDA
UniProt ID: (Human) P35611
Entrez Gene ID: (Human) 118
actin binding
structural molecule activity
calmodulin binding
transcription factor binding
spectrin binding
protein homodimerization activity
poly(A) RNA binding
protein heterodimerization activity
actin filament binding
cadherin binding involved in cell-cell adhesion
non-motor actin binding protein
cell morphogenesis
in utero embryonic development
cell volume homeostasis
hemoglobin metabolic process
actin cytoskeleton organization
erythrocyte differentiation
positive regulation of protein binding
multicellular organism growth
IRE1-mediated unfolded protein response
homeostasis of number of cells within a tissue
barbed-end actin filament capping
actin filament bundle assembly
transmembrane transport
cell-cell adhesion
