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Product Details
PA5-61254
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Recombinant protein corresponding to Human Alsin. Recombinant protein control fragment (Product #RP-95946).
Conjugate
Unconjugated
Form
Liquid
Concentration
0.1 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.2, with 40% glycerol
Contains
0.02% sodium azide
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Wet ice
RRID
AB_2637895
Product Specific Information
Immunogen sequence: FQPGLYYSGR QDPTEGDNLP ENHSGSKTPV LLSCSKLGYI SRVTAGKDSY LALVDKNIMG YIASLHELAT TERRFYSKLS D
Highest antigen sequence identity to the following orthologs: Mouse - 91%, Rat - 91%.
Target Information
The function of this protein remains unknown.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: Alsin; amyotrophic lateral sclerosis 2 (juvenile); Amyotrophic lateral sclerosis 2 chromosomal region candidate gene 6 protein; Amyotrophic lateral sclerosis 2 protein; FLJ31851; MGC87187
Gene Aliases: ALS2; ALS2CR6; ALSJ; IAHSP; KIAA1563; PLSJ
UniProt ID: (Human) Q96Q42
Entrez Gene ID: (Human) 57679
guanyl-nucleotide exchange factor activity
Ran guanyl-nucleotide exchange factor activity
protein binding
Rab guanyl-nucleotide exchange factor activity
Rab GTPase binding
Rac guanyl-nucleotide exchange factor activity
protein homodimerization activity
protein serine/threonine kinase activator activity
behavioral fear response
in utero embryonic development
receptor recycling
response to oxidative stress
endosome organization
axonogenesis
neuromuscular junction development
locomotory behavior
protein localization
cell death
vesicle organization
endosomal transport
Rac protein signal transduction
positive regulation of Rac protein signal transduction
regulation of Rho protein signal transduction
synaptic transmission, glutamatergic
positive regulation of GTPase activity
positive regulation of protein kinase activity
neuron projection morphogenesis
regulation of endosome size
positive regulation of protein serine/threonine kinase activity
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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