Invitrogen

Angiopoietin 4 Polyclonal Antibody

Angiopoietin 4 Antibody in Immunohistochemistry (Paraffin) (IHC (P))

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Angiopoietin 4 Antibody (PA5-34646) in IHC (P)

Immunohistochemistry (Paraffin) analysis of Angiopoietin 4 was performed in paraffin-embedded mouse duodenum tissue using Angiopoietin 4 Polyclonal Antibody (Product # PA5-34646) at a dilution of 1:500.

Angiopoietin 4 Antibody in Western Blot (WB)

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产品信息

PA5-34646

应用

建议稀释比

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免疫印迹 (WB)

1:500-1:3,000

免疫组化（石蜡） (IHC (P))

1:100-1:1,000

产品规格

种属反应

Human, Mouse

宿主/亚型

Rabbit / IgG

分类

Polyclonal

类型

Antibody

抗原

Recombinant protein fragment contains a sequence corresponding to a region within amino acids 1 and 108 (Q9Y264) of Angiopoietin 4

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偶联物

Unconjugated Unconjugated Unconjugated

形式

Liquid

浓度

1 mg/mL

纯化类型

Antigen affinity chromatography

保存液

0.1M tris glycine, pH 7, with 10% glycerol

内含物

0.01% thimerosal

保存条件

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

运输条件

Wet ice

RRID

AB_2551998

产品详细信息

Recommended positive controls: A431, H1299, HeLaS3, HepG2, Molt-4, Raji.

Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.

靶标信息

Angiopoietin-1 (Ang-1) is a secreted ligand for Tie-2, a cell surface receptor tyrosine kinase expressed in endothelial and hemopoietic cells. Ang-1 is an angiogenic factor that mediates blood vessel maturation and may be involved in endothelial development. A related protein, angiopoietin-2 (Ang-2), is a naturally occurring antagonist of Ang-1 activation of Tie-2. In adult tissue, Ang-2 expression is restricted to sites of vascular remodeling. Ang-3 and Ang-4 represent the mouse and human counterparts of the same gene locus. The structural divergence of Ang-3 and Ang-4 cause their divergent functions. Ang-3 and Ang-4 have very different distributions in their respective species, and Ang-3 appears to act as an antagonist while Ang-4 appears to function as an agonist. Ang-3 and Ang-4 share all the main structural characteristics of Ang-1 and Ang-2 and are homologous throughout the signal peptide, N-terminal region, coiled-coil segment and Fibrinogen-like domain.

⚠WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm. For more information go to www.P65Warnings.ca.gov.

仅用于科研。不用于诊断过程。未经明确授权不得转售。