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This gene encodes an actin-binding protein that plays a role in cell growth and migration, and in cytokinesis. The encoded protein is thought to regulate actin cytoskeletal dynamics in podocytes, components of the glomerulus. Mutations in this gene are associated with focal segmental glomerulosclerosis 8. Alternative splicing results in multiple transcript variants encoding different isoforms.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: Anillin; DKFZp779A055
基因别名: ANLN; FSGS8; scra; Scraps
UniProt ID: (Human) Q9NQW6
Entrez Gene ID: (Human) 54443
分子生物学功能: non-motor actin binding protein