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Additional Information: This antibody is expected to recognise both reported isoforms (NP_001140.2; NP_066267.2).
This antibody is tested in Peptide ELISA: antibody detection limit dilution 1:16,000.
Ankyrin-G is found in several tissues including brain where, due to tissue-specific RNA processing, it is expressed as two different isoforms, localized to axon initial segments and nodes of Ranvier. Ankyrin-G is also found at sites of epithelial cell-cell contact and in the intracellular membranes of some cells. Ankyrin-G isoforms contain a unique stretch of sequence highly enriched in serine and threonine residues immediately following a globular head domain. Ankyrin-G is thought to participate in the maintenance and targeting of ion channels and cell adhesion molecules to the nodes of Ranvier and to axon initial segments.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: ANK-3; Ankyrin-3; Ankyrin-G
基因别名: ANK3; ANKYRIN-G; MRT37
UniProt ID: (Human) Q12955
Entrez Gene ID: (Human) 288