Target of Interest
Search Thermo Fisher Scientific
Disclaimer
Clicking the images or links will redirect you to a website hosted by BenchSci that provides third-party scientific content. Neither the content nor the BenchSci technology and processes for selection have been evaluated by us; we are providing them as-is and without warranty of any kind, including for use or application of the Thermo Fisher Scientific products presented.
Application
图: 1 / 3
Annexin A4 Antibody (PA5-27871) in IHC (P)
Annexin A4 Polyclonal Antibody detects ANXA4 protein at cytosol and membrane on D54MG xenograft by immunohistochemical analysis. Sample: Paraffin-embedded D54MG xenograft. Annexin A4 Polyclonal Antibody (Product # PA5-27871) dilution: 1:500. Antigen Retrieval: EDTA based buffer, pH 8.0, 15 min.
产品信息
PA5-27871
应用
建议稀释比
已发表文章
产品规格
种属反应
Human
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
Recombinant fragment corresponding to a region within amino acids 1 and 319 of Human Annexin A4
偶联物
Unconjugated
形式
Liquid
浓度
1 mg/mL
纯化类型
Antigen affinity chromatography
保存液
0.1M tris glycine, pH 7, with 20% glycerol
内含物
0.01% thimerosal
保存条件
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
运输条件
Ambient (domestic); Wet ice (international)
RRID
AB_2545347
产品详细信息
Recommended positive controls: HepG2.
Predicted reactivity: Mouse (92%), Rat (92%), Dog (93%), Pig (96%), Rhesus Monkey (98%), Bovine (94%).
Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.
靶标信息
Annexin IV (ANX4) belongs to the annexin family of calcium-dependent phospholipid binding proteins. Although their functions are still not clearly defined, several members of the annexin family have been implicated in membrane-related events along exocytotic and endocytotic pathways. ANX4 has 45 to 59% identity with other members of its family and shares a similar size and exon-intron organization. Isolated from human placenta, ANX4 encodes a protein that has possible interactions with ATP, and has in vitro anticoagulant activity and also inhibits phospholipase A2 activity. ANX4 is almost exclusively expressed in epithelial cells.
⚠WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm. For more information go to www.P65Warnings.ca.gov.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
篇参考文献 (0)
您是否在文献中引用过该产品？请点击下方按钮邮件告知我们。
生物信息学
蛋白别名: 35-beta calcimedin; Annexin A4; Annexin IV; annexin IV (placental anticoagulant protein II); Annexin-4; ANXA 4; Carbohydrate-binding protein p33/p41; Chromobindin-4; Endonexin I; epididymis secretory protein Li 274; Lipocortin IV; P32.5; PAP-II; Placental anticoagulant protein II; PP4-X; proliferation-inducing gene 28; proliferation-inducing protein 28; Protein II
基因别名: ANX4; ANXA4; HEL-S-274; P32.5; PAP-II; PIG28; PP4-X; ZAP36
UniProt ID: (Human) P09525
Entrez Gene ID: (Human) 307
regulation of transcription from RNA polymerase II promoter
signal transduction
Notch signaling pathway
epithelial cell differentiation
negative regulation of NF-kappaB transcription factor activity
negative regulation of apoptotic process
negative regulation of catalytic activity
negative regulation of interleukin-8 secretion
