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Immunogen sequence: NLERIVMALL QPTAQFDAQE LRTALKASDS AVDVAIEILA TRTPPQLQEC LAVYKHNFQV EAVDDITSET SGIL
Highest antigen sequence identity to the following orthologs: Mouse - 77%, Rat - 77%.
The annexins include ANXA9 coded protein, which are a family of calcium-dependent phospholipid-binding proteins. Members of the annexin family contain 4 internal repeat domains, each of which includes a type II calcium-binding site. The calcium-binding sites are required for annexins to aggregate and cooperatively bind anionic phospholipids and extracellular matrix proteins. Annexin A9 is a divergent member of the annexin protein family in which all four homologous type II calcium-binding sites in the conserved tetrad core contain amino acid substitutions that ablate their function. However, structural analysis suggests that the conserved putative ion channel formed by the tetrad core is intact.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: annexin 31; Annexin A9; Annexin XXXI; Annexin-31; Annexin-9; Pemphaxin
Gene Aliases: ANX31; ANXA9
UniProt ID: (Human) O76027
Entrez Gene ID: (Human) 8416
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