Invitrogen

ApoC3 Recombinant Superclonal Antibody (6HCLC)

ApoC3 Antibody in Immunocytochemistry (ICC/IF)

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ApoC3 Antibody (710262) in ICC/IF

Immunofluorescent analysis of ApoC3 in HepG2 cells using an ApoC3 Recombinant Rabbit Polyclonal Antibody (Product # 710262) followed by detection using an Alexa Fluor 488-conjugated Goat anti-Rabbit secondary antibody (green) (Image A). Nuclei were stained using DAPI (Image B) and actin stained with Alexa Fluor 594 phalloidin (red) (image C). Image D is a composite image showing subcellular cytoplasmic localization of Apo C3.

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产品信息

710262

应用

建议稀释比

已发表文章

免疫印迹 (WB)

1-3 µg/mL

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免疫细胞化学 (ICC/IF)

1-3 µg/mL

产品规格

种属反应

Human, Rat

已发表种属

Not Applicable

宿主/亚型

Rabbit / IgG

Expression System

Expi293

分类

Recombinant Superclonal

类型

Antibody

克隆号

6HCLC

抗原

Peptide corresponding to amino acids 37-48 of human Apolipoprotein C3

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偶联物

Unconjugated Unconjugated Unconjugated

形式

Liquid

浓度

0.5 mg/mL

纯化类型

Protein A

保存液

PBS

内含物

0.09% sodium azide

保存条件

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

运输条件

Wet ice

RRID

AB_2532651

产品详细信息

This antibody is predicted to react with mouse, non-human primate, rabbit and porcine based on sequence homology.

Recombinant rabbit polyclonal antibodies are unique offerings from Thermo Fisher Scientific. They are comprised of a selection of multiple different recombinant monoclonal antibodies, providing the best of both worlds - the sensitivity of polyclonal antibodies with the specificity of monoclonal antibodies - all delivered with the consistency only found in a recombinant antibody. While functionally the same as a polyclonal antibody - recognizing multiple epitope sites on the target and producing higher detection sensitivity for low abundance targets - a recombinant rabbit polyclonal antibody has a known mixture of light and heavy chains. The exact population can be produced in every lot, circumventing the biological variability typically associated with polyclonal antibody production.

靶标信息

Apolipoprotein C-III, also known as apo-CIII, is a protein that in humans is encoded by the APOC3 gene. Apo-CIII is a component of very low density lipoprotein (VLDL). APOC3 inhibits lipoprotein lipase and hepatic lipase; it is thought to delay catabolism of triglyceride-rich particles. The APOA1, APOC3 and APOA4 genes are closely linked in both rat and human genomes. The A-I and A-IV genes are transcribed from the same strand, while the A-1 and C-III genes are convergently transcribed. An increase in apoC-III levels induces the development of hypertriglyceridemia.

仅用于科研。不用于诊断过程。未经明确授权不得转售。