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Aquaporin 1 Antibody (MA5-54118) in ICC/IF
Immunocytochemistry analysis of Aquaporin 1 in C2C12 cells. Nuclei were stained blue with DAPI; Aquaporin 1 recombinant monoclonal antibody (Product # MA5-54118) with a dilution of 1:1,000 was stained magenta with Alexa Fluor 647. Images were taken using Leica stellaris 5. Protein abundance based on laser Intensity and smart gain: Medium. Scale bar: 20 μm.
产品信息
MA5-54118
产品规格
种属反应
Human
宿主/亚型
Rabbit
/ IgG
Expression System
HEK293F
分类
Recombinant Monoclonal
类型
Antibody
克隆号
23GB1850
抗原
A synthesized peptide derived from human AQP1 (214-269AA).
偶联物
形式
Liquid
纯化类型
Affinity chromatography
保存液
PBS, pH 7.4, with 50% glycerol
内含物
0.02% sodium azide
保存条件
-20°C
运输条件
Wet ice (domestic); Dry ice (international)
靶标信息
Aquaporin 1 is a 28kD integral membrane protein which was originally identified in red blood cells and renal proximal tubules. AQP1 is also expressed by the choroid plexus and various other tissues. It forms a water-specific channel that provides the plasma membranes of red cells and kidney proximal tubules with high permeability to water, thereby permitting water to move in the direction of an osmotic gradient.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: AQP 1; AQP CHIP; AQP-1; aquaporin 1 (channel-forming integral protein, 28kDa, CO blood group); aquaporin 1, Colton blood group antigen; Aquaporin CHIP; Aquaporin-1; Aquaporin-CHIP; Aquaporin1; channel-like integral membrane protein, 28-kDa; CHIP 28; Colton blood group; MGC26324; Urine water channel; Water channel protein for red blood cells and kidney proximal tubule
基因别名: AQP-CHIP; AQP1; CHIP28; CO
UniProt ID: (Human) P29972
Entrez Gene ID: (Human) 358
intracellular cGMP activated cation channel activity
potassium channel activity
water transmembrane transporter activity
protein binding
ammonium transmembrane transporter activity
potassium ion transmembrane transporter activity
glycerol transmembrane transporter activity
water channel activity
glycerol channel activity
transmembrane transporter activity
nitric oxide transmembrane transporter activity
carbon dioxide transmembrane transporter activity
transporter
renal water homeostasis
renal water transport
cGMP biosynthetic process
potassium ion transport
water transport
cell volume homeostasis
cellular water homeostasis
carbon dioxide transport
ammonium transport
bicarbonate transport
glycerol transport
cellular homeostasis
lateral ventricle development
pancreatic juice secretion
nitric oxide transport
establishment or maintenance of actin cytoskeleton polarity
cerebrospinal fluid secretion
cellular response to stress
cellular response to UV
transepithelial water transport
carbon dioxide transmembrane transport
odontogenesis
response to drug
negative regulation of apoptotic process
negative regulation of cysteine-type endopeptidase activity involved in apoptotic process
positive regulation of angiogenesis
positive regulation of saliva secretion
positive regulation of fibroblast proliferation
multicellular organismal water homeostasis
cellular response to hydrogen peroxide
cellular response to inorganic substance
cellular response to mechanical stimulus
cellular response to copper ion
cellular response to mercury ion
cellular response to retinoic acid
cellular response to cAMP
cellular response to hypoxia
cellular response to salt stress
cellular hyperosmotic response
cellular response to dexamethasone stimulus
cellular response to nitric oxide
potassium ion transmembrane transport
ammonium transmembrane transport
maintenance of symbiont-containing vacuole by host
