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Recommended positive controls: H1299, HeLa, HepG2, Molt-4, Raji, NIH-3T3.
Predicted reactivity: Mouse (100%), Rat (99%), Xenopus laevis (98%), Pig (100%), Chicken (99%), Rhesus Monkey (100%), Bovine (100%).
Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.
ARP2 (actin-related protein 2) is an ATP-binding component of the ARP2/3 complex - a multiprotein complex that mediates actin polymerization upon stimulation by the nucleation-promoting factor (NPF). The ARP2/3 complex mediates the formation of branched actin networks in the cytoplasm and provides the force for cell motility. The ARP2/3 complex also promotes actin polymerization in the nucleus, thereby regulating gene transcription and repair of damaged DNA.
⚠WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm. For more information go to www.P65Warnings.ca.gov.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: Actin-like protein 2; Actin-related protein 2; ARP2 actin-related protein 2 homolog
基因别名: 4921510D23Rik; AA409782; ACTR2; ARP2; D6Ertd746e
UniProt ID: (Human) P61160, (Rat) Q5M7U6, (Mouse) P61161
Entrez Gene ID: (Human) 10097, (Rat) 289820, (Mouse) 66713
分子生物学功能: actin and actin related protein actin or actin-binding cytoskeletal protein cytoskeletal protein