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Percent identity with other species by BLAST analysis: Human, Gibbon (100%); Monkey, Marmoset, Mouse, Rat, Dog, Hamster, Rabbit (93%); Gorilla, Bovine, Panda (87%); Bat, Pig (80%).
For IHC(P), use heat induced antigen retrieval in pH 6.0 citrate buffer. After incubation with the primary antibody, slides were incubated with biotinylated secondary antibody, followed by alkaline phosphatase-streptavidin and chromogen.
Multiple transcript variants encoding different isoforms exist for this gene. One of the isoforms is a membrane-bound protein with sequence similarity to the mouse mahogany protein, a receptor involved in controlling obesity. The other isoform is a secreted protein involved in the initial immune cell clustering during inflammatory responses that may regulate the chemotactic activity of chemokines.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: Attractin; attractin-2; DPPT-L; Mahogany homolog; mahogany protein; MGC126754
基因别名: ATRN; DPPT-L; KIAA0548; MGCA
UniProt ID: (Human) O75882
Entrez Gene ID: (Human) 8455
分子生物学功能:
basic leucine zipper transcription factor
extracellular matrix protein