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Percent identity with other species by BLAST analysis: Human, Gibbon, Marmoset, Mouse, Rat, Dog, Bat, Hamster, Panda, Pig (100%); Gorilla, Monkey, Rabbit (94%); Elephant (88%); Bovine, Stickleback (82%).
For IHC(P), use heat induced antigen retrieval in pH 6.0 citrate buffer. After incubation with the primary antibody, slides were incubated with biotinylated secondary antibody, followed by alkaline phosphatase-streptavidin and chromogen.
Multiple transcript variants encoding different isoforms exist for this gene. One of the isoforms is a membrane-bound protein with sequence similarity to the mouse mahogany protein, a receptor involved in controlling obesity. The other isoform is a secreted protein involved in the initial immune cell clustering during inflammatory responses that may regulate the chemotactic activity of chemokines.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: atrn {ECO:0000312|RGD:69063}; Attractin; attractin-2; DPPT-L; mahogany; Mahogany homolog; mahogany protein; membrane attractin; MGC126754; Protein mahogany; Protein zitter
基因别名: ATRN; AW558010; DPPT-L; I79_005027; KIAA0548; mahogany; Mg; MGCA; mKIAA0548
UniProt ID: (Human) O75882, (Rat) Q99J86, (Mouse) Q9WU60
Entrez Gene ID: (Pig) 100101470, (Human) 8455, (Dog) 477170, (Rat) 83526, (Chinese hamster) 100774269, (Mouse) 11990
分子生物学功能:
cell adhesion molecule
basic leucine zipper transcription factor
extracellular matrix protein