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B2 Bradykinin Receptor (BDKRB2) Antibody (ABR-012-200UL) in IHC
Expression ofB2bradykinin receptorin mouse spinal cord - Immunohistochemical staining of mouse spinal cord using Anti-B2Bradykinin Receptor (BDKRB2) Antibody (#ABR-012). A. BKR2 (red) appears in several spinal cord neurons (triangles). B. Parvalbumin (green) appears in neurons. C. Merge of BKR2and parvalbumin shows co-expression in several neurons (triangles) but not all (arrow in C). DAPI is used as the co... View More
产品信息
ABR-012-200UL
产品规格
种属反应
Human,
Mouse,
Rat
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
GKRFRKKSWEVYQG(C), corresponding to amino acid residues 336-349 of human B2R, Intracellular, C-terminus
偶联物
Unconjugated
形式
Lyophilized
浓度
0.75 mg/mL
纯化类型
Antigen affinity chromatography
保存液
PBS, pH 7.4, with 1% BSA
内含物
0.05% sodium azide
保存条件
-20° C, Avoid Freeze/Thaw Cycles
运输条件
Ambient (domestic); Wet ice (international)
产品详细信息
Reconstitution: 25 µL, 50 µL or 0.2 mL double distilled water (DDW), depending on the sample size. The antibody ships as a lyophilized powder at room temperature. Upon arrival, it should be stored at -20C. The reconstituted solution can be stored at 4C for up to 1 week. For longer periods, small aliquots should be stored at -20C. Avoid multiple freezing and thawing. Centrifuge all antibody preparations before use (10000 x g 5 min).
靶标信息
Bradykinin B2 receptor (BDKRB2) expression has been reported in blood, brain, eye, kidney, liver, lung, prostate, skin, small intestine, synovium, uterus, and vessel. ESTs have been isolated from colon, connective tissue, heart, heart/melanocyte/uterus, and kidney libraries. It is associated with G-proteins that activate a phosphatidylinositol-calcium second messenger system.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: B2 bradykinin receptor; B2R; BK-2 receptor; BK-2R; BK-2Rs; bradykinin receptor, beta 2; DKFZp686O088; kinin B2
基因别名: B(2); B2; B2BKR; B2BRA; B2R; BDKRB2; BK-2; BK2; BK2R; BKR2; BRB2
UniProt ID: (Human) P30411, (Mouse) P32299, (Rat) P25023
Entrez Gene ID: (Human) 624, (Mouse) 12062, (Rat) 25245
protease binding
phosphatidylinositol phospholipase C activity
bradykinin receptor activity
protein binding
beta-2 adrenergic receptor binding
type 1 angiotensin receptor binding
protein heterodimerization activity
signal transducer activity
G-protein coupled receptor activity
G-protein coupled receptor
acute inflammatory response to antigenic stimulus
smooth muscle contraction
inflammatory response
cell surface receptor signaling pathway
transmembrane receptor protein tyrosine kinase signaling pathway
G-protein coupled receptor signaling pathway
positive regulation of cytosolic calcium ion concentration
blood circulation
negative regulation of cell proliferation
response to salt stress
regulation of vasoconstriction
negative regulation of peptidyl-serine phosphorylation
maintenance of blood-brain barrier
vasoconstriction
vasodilation
response to drug
regulation of vascular permeability
negative regulation of blood pressure
arachidonic acid secretion
cellular response to hypoxia
negative regulation of intrinsic apoptotic signaling pathway in response to osmotic stress by p53 class mediator
response to stress
signal transduction
negative regulation of intrinsic apoptotic signaling pathway in response to osmotic stress
sensory perception of pain
