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B3GNT5 Antibody (PA5-89820) in WB
Western blot analysis of B3GNT5 in extracts of various cell lines. Samples were incubated with B3GNT5 Polyclonal antibody (Product # PA5-89820) using a dilution of 1:3,000, followed by HRP Goat Anti-Rabbit IgG (H+L) at a dilution of 1:10,000. Lysates/proteins: 25 µg per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit. Exposure time: 30s.
产品信息
PA5-89820
产品规格
种属反应
Human
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
Recombinant fusion protein containing a sequence corresponding to amino acids 36-378 of human B3GNT5 (NP_1144361)
偶联物
形式
Liquid
浓度
2.03 mg/mL
纯化类型
Affinity Chromatography
保存液
PBS, pH 7.3, with 50% glycerol
内含物
0.01% thimerosal
保存条件
-20° C, Avoid Freeze/Thaw Cycles
运输条件
Wet ice
RRID
AB_2805792
产品详细信息
Immunogen sequence: DNHIVSHMKS YSYRYLINSY DFVNDTLSLK HTSAGPRYQY LINHKEKCQA QDVLLLLFVK TAPENYDRRS GIRRTWGNEN YVRSQLNANI KTLFALGTPN PLEGEELQRK LAWEDQRYND IIQQDFVDSF YNLTLKLLMQ FSWANTYCPH AKFLMTADDD IFIHMPNLIE YLQSLEQIGV QDFWIGRVHR GAPPIRDKSS KYYVSYEMYQ WPAYPDYTAG AAYVISGDVA AKVYEASQTL NSSLYIDDVF MGLCANKIGI VPQDHVFFSG EGKTPYHPCI YEKMMTSHGH LEDLQDLWKN ATDPKVKTIS KGFFGQIYCR LMKIILLCKI SYVDTYPCRA AFI; Positive Samples: HT-29, A-549; Cellular Location: Golgi apparatus membrane, Single-pass type II membrane protein
靶标信息
B3GNT5 is a member of the beta-1,3-N-acetylglucosaminyltransferase family. This enzyme is a type II membrane protein. It exhibits strong activity to transfer GlcNAc to glycolipid substrates and is identified as the most likely candidate for lactotriaosylceramide synthase. This enzyme is essential for the expression of Lewis X epitopes on glycolipids.
⚠WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm. For more information go to www.P65Warnings.ca.gov.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: beta 1,3 N-acetyglucosaminyltransferase Lc3 synthase; beta-1,3-Gn-T5; beta-1,3-N-acetylglucosaminyltransferase 5; beta-1,3-N-acetylglucosaminyltransferase bGnT-5; BGnT-5; Lactosylceramide 1,3-N-acetyl-beta-D-glucosaminyltransferase; Lactotriaosylceramide synthase; Lc(3)Cer synthase; lc3 synthase; UDP-GlcNAc:beta-Gal beta-1,3-N-acetylglucosaminyltransferase 5
基因别名: B3GN-T5; B3GNT5; beta3Gn-T5
UniProt ID: (Human) Q9BYG0
Entrez Gene ID: (Human) 84002
