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产品信息
H00007917-B01P
产品规格
种属反应
Human
宿主/亚型
Mouse
/ IgG
分类
Polyclonal
类型
Antibody
抗原
BAT3 (NP_542433.1, 1 a.a. approximately 1126 a.a) full-length human protein.
偶联物
Unconjugated
形式
Liquid
浓度
See Label
纯化类型
Affinity chromatography
保存液
PBS, pH 7.4
内含物
no preservative
保存条件
-20° C, Avoid Freeze/Thaw Cycles
运输条件
Ambient (domestic); Wet ice (international)
产品详细信息
Sequence of this protein is as follows: MEPNDSTSTA VEEPDSLEVL VKTLDSQTRT FIVGAQMNVK EFKEHIAASV SIPSEKQRLI YQGRVLQDDK KLQEYNVGGK VIHLVERAPP QTHLPSGASS GTGSASATHG GGSPPGTRGP GASVHDRNAN SYVMVGTFNL PSDGSAVDVH INMEQAPIQS EPRVRLVMAQ HMIRDIQTLL SRMECRGGPQ PQHSQPPPQP PAVTPEPVAL SSQTSEPVES EAPPREPMEA EEVEERAPAQ NPELTPGPAP AGPTPAPETN APNHPSPAEY VEVLQELQRL ESRLQPFLQR YYEVLGAAAT TDYNNNHEGR EEDQRLINLV GESLRLLGNT FVALSDLRCN LACTPPRHLH VVRPMSHYTT PMVLQQAAIP IQINVGTTVT MTGNGTRPPP TPNAEAPPPG PGQASSVAPS STNVESSAEG APPPGPAPPP ATSHPRVIRI SHQSVEPVVM MHMNIQDSGT QPGGVPSAPT GPLGPPGHGQ TLGQQVPGFP TAPTRVVIAR PTPPQARPSH PGGPPVSGTL QGAGLGTNAS LAQMVSGLVG QLLMQPVLVA QGTPGMAPPP APATASASAG TTNTATTAGP APGGPAQPPP TPQPSMADLQ FSQLLGNLLG PAGPGAGGSG VASPTITVAM PGVPAFLQGM TDFLQATQTA PPPPPPPPPP PPAPEQQTMP PPGSPSGGAG SPGGLGLESL SPEFFTSVVQ GVLSSLLGSL GARAGSSESI AAFIQRLSGS SNIFEPGADG ALGFFGALLS LLCQNFSMVD VVMLLHGHFQ PLQRLQPQLR SFFHQHYLGG QEPTPSNIRM ATHTLITGLE EYVRESFSLV QVQPGVDIIR TNLEFLQEQF NSIAAHVLHC TDSGFGARLL ELCNQGLFEC LALNLHCLGG QQMELAAVIN GRIRRMSRGV NPSLVSWLTT MMGLRLQVVL EHMPVGPDAI LRYVRRVGDP PQPLPEEPME VQGAERASPE PQRENASPAP GTTAEEAMSR GPPPAPEGGS RDEQDGASAE TEPWAAAVPP EWVPIIQQDI QSQRKVKPQP PLSDAYLSGM PAKRRKTMQG EGPQLLLSEA VSRAAKAAGA RPLTSPESLS RDLEAPEVQE SYRQQLRSDI QKRLQEDPNY SPQRFPNAQR AFADDP
靶标信息
This gene was first characterized as part of a cluster of genes located within the human major histocompatibility complex class III region. This gene encodes a nuclear protein that is cleaved by caspase 3 and is implicated in the control of apoptosis. In addition, the protein forms a complex with E1A binding protein p300 and is required for the acetylation of p53 in response to DNA damage. Multiple transcript variants encoding different isoforms have been found for this gene.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: BAG 6; BAG family molecular chaperone regulator 6; BAG-6; BAT 3; BCL2-associated athanogene 6; DAQB-195H10.3; HLA-B associated transcript 3; HLA-B associated transcript-3; HLA-B-associated transcript 3; Large proline-rich protein BAG6; large proline-rich protein BAT3; Protein G3; Protein Scythe; scythe
基因别名: BAG-6; BAG6; BAT3; D6S52E; G3
UniProt ID: (Human) Q5SQ35
Entrez Gene ID: (Human) 7917
kidney development
immune system process
ubiquitin-dependent protein catabolic process
transport
synaptonemal complex assembly
spermatogenesis
brain development
embryo development
covalent chromatin modification
internal peptidyl-lysine acetylation
cell differentiation
lung development
negative regulation of proteasomal ubiquitin-dependent protein catabolic process
regulation of cell proliferation
intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator
negative regulation of apoptotic process
negative regulation of proteolysis
protein stabilization
intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress
tail-anchored membrane protein insertion into ER membrane
positive regulation of ERAD pathway
maintenance of unfolded protein involved in ERAD pathway
protein localization to cytosolic proteasome complex involved in ERAD pathway
