Invitrogen

BBS2 Polyclonal Antibody

BBS2 Antibody in Immunohistochemistry (Paraffin) (IHC (P))

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BBS2 Antibody (PA5-59513) in IHC (P)

Immunohistochemical analysis of BBS2 in human fallopian tube using BBS2 Polyclonal Antibody (Product # PA5-59513) shows strong membranous and cytoplasmic positivity in ciliated cells.

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产品信息

PA5-59513

应用

建议稀释比

已发表文章

免疫组化（石蜡） (IHC (P))

1:50-1:200

产品规格

种属反应

Human

宿主/亚型

Rabbit / IgG

分类

Polyclonal

类型

Antibody

抗原

Recombinant protein corresponding to Human BBS2. Recombinant protein control fragment (Product #RP-98640).

查看免疫原

偶联物

Unconjugated Unconjugated Unconjugated

形式

Liquid

浓度

0.05 mg/mL

纯化类型

Antigen affinity chromatography

保存液

PBS, pH 7.2, with 40% glycerol

内含物

0.02% sodium azide

保存条件

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

运输条件

Wet ice

RRID

AB_2638488

产品详细信息

Immunogen sequence: IVTSLCPMYG SRFGYALSNG TVGVYDKTSR YWRIKSKNHA MSIHAFDLNS DGVNELITGW SNGKVDARSD RTGEVIFKDN FSSAIAGVVE GDYRMDG

Highest antigen sequence identity to the following orthologs: Mouse - 96%, Rat - 96%.

靶标信息

This gene is a member of the Bardet-Biedl syndrome (BBS) gene family. Bardet-Biedl syndrome is an autosomal recessive disorder characterized by severe pigmentary retinopathy, obesity, polydactyly, renal malformation and mental retardation. The proteins encoded by BBS gene family members are structurally diverse and the similar phenotypes exhibited by mutations in BBS gene family members is likely due to their shared roles in cilia formation and function. Many BBS proteins localize to the basal bodies, ciliary axonemes, and pericentriolar regions of cells. BBS proteins may also be involved in intracellular trafficking via microtubule-related transport. The protein encoded by this gene forms a multiprotein BBSome complex with six other BBS proteins.

仅用于科研。不用于诊断过程。未经明确授权不得转售。