Invitrogen

BEND3 Polyclonal Antibody

BEND3 Antibody in Immunohistochemistry (Paraffin) (IHC (P))

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BEND3 Antibody (PA5-117808) in IHC (P)

Immunohistochemical staining of human BEND3 in human liver with BEND3 Polyclonal Antibody (Product # PA5-117808, 1:100 dilution, formalin-fixed paraffin embedded sections).

BEND3 Antibody in Immunoprecipitation (IP)

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产品信息

PA5-117808

应用

建议稀释比

已发表文章

免疫印迹 (WB)

1:500-1:2,000

免疫组化（石蜡） (IHC (P))

1:50-1:200

免疫沉淀 (IP)

0.5-1 µL/mg of lysate

产品规格

种属反应

Human

宿主/亚型

Rabbit / IgG

分类

Polyclonal

类型

Antibody

抗原

E. coli-derived Human BEND3 fragment

偶联物

Unconjugated Unconjugated Unconjugated

形式

Liquid

纯化类型

Antigen affinity chromatography, Protein A

保存液

PBS, pH 7

内含物

0.03% ProClin 300

保存条件

-20° C, Avoid Freeze/Thaw Cycles

运输条件

Wet ice

RRID

AB_2902418

靶标信息

Transcriptional repressor which associates with the NoRC (nucleolar remodeling complex) complex and plays a key role in repressing rDNA transcription. The sumoylated form modulates the stability of the NoRC complex component BAZ2A/TIP5 by controlling its USP21-mediated deubiquitination (PubMed:21914818, PubMed:26100909). Binds to unmethylated major satellite DNA and is involved in the recruitment of the Polycomb repressive complex 2 (PRC2) to major satellites. Stimulates the ERCC6L translocase and ATPase activities (PubMed:28977671). [UniProt]

仅用于科研。不用于诊断过程。未经明确授权不得转售。