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产品信息
PA5-96637
产品规格
种属反应
Human,
Mouse,
Rat
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
Recombinant fusion protein containing a sequence corresponding to amino acids 143-392 of human BMP15 (NP_0054392)
偶联物
Unconjugated
形式
Liquid
浓度
2.35 mg/mL
纯化类型
Affinity Chromatography
保存液
PBS, pH 7.3, with 50% glycerol
内含物
0.02% sodium azide
保存条件
-20° C, Avoid Freeze/Thaw Cycles
运输条件
Ambient (domestic); Wet ice (international)
RRID
AB_2808439
产品详细信息
Immunogen sequence: LTRFNLSCHV EPWVQKNPTN HFPSSEGDSS KPSLMSNAWK EMDITQLVQQ RFWNNKGHRI LRLRFMCQQQ KDSGGLELWH GTSSLDIAFL LLYFNDTHKS IRKAKFLPRG MEEFMERESL LRRTRQADGI SAEVTASSSK HSGPENNQCS LHPFQISFRQ LGWDHWIIAP PFYTPNYCKG TCLRVLRDGL NSPNHAIIQN LINQLVDQSV PRPSCVPYKY VPISVLMIEA NGSILYKEYE GMIAESCTCR; Positive Samples: OVCAR3, Mouse brain, Mouse kidney, Mouse liver, Rat brain
靶标信息
BMP15, or GDF9B is a member of the bone morphogenetic protein family which is part of the transforming growth factor-beta superfamily that are involved in embryonic development and adult tissue homeostasis. BMP15 is expressed exclusively in the oocyte. It is an oocyte-specific growth/differentiation factor that may be involved in oocyte maturation and follicular development. Defects in BMP15 are the cause of ovarian dysgenesis type 2. BMP15 could be used as an oogenesis marker to track human amniotic fluid stem cells differentiation into the oocyte-like cells.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: BMP; BMP-15; Bone morphogenetic protein; Bone morphogenetic protein 15; GDF-9B; growth differentiation factor-9B; Growth/differentiation factor 9B
基因别名: AU015375; AU018861; AU021453; Bmp-15; BMP15; C86824; C87336; GDF-9B; GDF9B; ODG2; POF4
UniProt ID: (Human) O95972, (Mouse) Q9Z0L4
Entrez Gene ID: (Human) 9210, (Rat) 59302, (Mouse) 12155
ovarian follicle development
female gamete generation
positive regulation of pathway-restricted SMAD protein phosphorylation
BMP signaling pathway
regulation of apoptotic process
regulation of MAPK cascade
cell development
granulosa cell development
SMAD protein signal transduction
positive regulation of transcription, DNA-templated
