Abnova

BMP7 Monoclonal Antibody (S52)

查看其他24个BMP-7抗体

抗体检测数据 (6)

BMP7 Antibody in Western Blot (WB)

BMP7 Antibody in Western Blot (WB)

图: 1 / 6

BMP7 Antibody (H00000655-M03) in WB

Western Blot analysis of BMP7 expression in transfected 293T cell line by BMP7 monoclonal antibody (M03), clone S52.

Lane 1: BMP7 transfected lysate(49.313 KDa).
Lane 2: Non-transfected lysate.

BMP7 Antibody in Western Blot (WB)

BMP7 Antibody in Western Blot (WB)

BMP7 Antibody in Western Blot (WB)

BMP7 Antibody in Western Blot (WB)

BMP7 Antibody in Western Blot (WB)

BMP7 Antibody in ELISA (ELISA)

Product Image Gallery

BMP7 Antibody in Western Blot (WB) — Western Blot analysis of BMP7 expression in transfected 293T cell line by BMP7 monoclonal antibody (M03), clone S52.

Lane 1: BMP7 transfected lysate(49.313 KDa).
Lane 2: Non-transfected lysate.

BMP7 Antibody in Western Blot (WB) — BMP7 monoclonal antibody (M03), clone S52. Western Blot analysis of BMP7 expression in A-549 (Cat # L025V1).

BMP7 Antibody in Western Blot (WB) — BMP7 monoclonal antibody (M03), clone S52. Western Blot analysis of BMP7 expression in human ovarian cancer.

BMP7 Antibody in Western Blot (WB) — BMP7 monoclonal antibody (M03), clone S52. Western Blot analysis of BMP7 expression in C32 (Cat # L002V1).

BMP7 Antibody in Western Blot (WB) — BMP7 monoclonal antibody (M03), clone S52. Western Blot analysis of BMP7 expression in Raw 264.7.

BMP7 Antibody in ELISA (ELISA) — Detection limit for recombinant GST tagged BMP7 is 10 ng/mL as a capture antibody.

产品信息

H00000655-M03

应用

建议稀释比

已发表文章

免疫印迹 (WB)

1-5 µg/mL

-

酶联免疫吸附实验 (ELISA)

10 ng/mL

-

产品规格

种属反应

Human, Mouse

宿主/亚型

Mouse / IgG1, kappa

分类

Monoclonal

类型

Antibody

克隆号

S52

抗原

BMP7 (AAH08584, 1 a.a. approximately 431 a.a) full-length recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.

查看免疫原

偶联物

Unconjugated Unconjugated Unconjugated

形式

Liquid

浓度

See Label

纯化类型

Affinity chromatography

保存液

PBS, pH 7.4

内含物

no preservative

保存条件

-20° C, Avoid Freeze/Thaw Cycles

运输条件

Ambient (domestic); Wet ice (international)

产品详细信息

Sequence of this protein is as follows: MHVRSLRAAA PHSFVALWAP LFLLRSALAD FSLDNEVHSS FIHRRLRSQE RREMQREILS ILGLPHRPRP HLQGKHNSAP MFMLDLYNAM AVEEGGGPGG QGFSYPYKAV FSTQGPPLAS LQDSHFLTDA DMVMSFVNLV EHDKEFFHPR YHHREFRFDL SKIPEGEAVT AAEFRIYKDY IRERFDNETF RISVYQVLQE HLGRESDLFL LDSRTLWASE EGWLVFDITA TSNHWVVNPR HNLGLQLSVE TLDGQSINPK LAGLIGRHGP QNKQPFMVAF FKATEVHFRS IRSTGSKQRS QNRSKTPKNQ EALRMANVAE NSSSDQRQAC KKHELYVSFR DLGWQDWIIA PEGYAAYYCE GECAFPLNSY MNATNHAIVQ TLVHFINPET VPKPCCAPTQ LNAISVLYFD DSSNVILKKY RNMVVRACGC H

靶标信息

The bone morphogenetic proteins (BMPs) are a family of secreted signaling molecules that can induce ectopic bone growth. Many BMPs are part of the transforming growth factor-beta (TGFB) superfamily. BMPs were originally identified by an ability of demineralized bone extract to induce endochondral osteogenesis in vivo in an extra skeletal site. Based on its expression early in embryogenesis, BMP7 has a proposed role in early development. In addition, the fact that BMP7 is closely related to BMP5 and BMP6 has lead to speculation of possible bone inductive activity.

仅用于科研。不用于诊断过程。未经明确授权不得转售。

篇参考文献 (0)

您是否在文献中引用过该产品？请点击下方按钮邮件告知我们。

引用该产品

生物信息学

蛋白别名: BMP; BMP-7; Bone morphogenetic protein; Bone morphogenetic protein 7; OP-1; Osteogenic protein 1; RP11-560A15.5

查看更多收起

基因别名: Bmp-7; BMP7; OP-1; OP1

查看更多收起

UniProt ID: (Human) P18075, (Mouse) P23359

查看更多收起

Entrez Gene ID: (Human) 655, (Mouse) 12162

查看更多收起

cytokine activity transforming growth factor beta receptor binding protein binding growth factor activity heparin binding BMP receptor binding growth factor

参与通路

skeletal system development ossification metanephros development ureteric bud development mesoderm formation mesonephros development epithelial to mesenchymal transition axon guidance embryonic pattern specification negative regulation of striated muscle cell apoptotic process positive regulation of peptidyl-threonine phosphorylation positive regulation of pathway-restricted SMAD protein phosphorylation dendrite development embryonic limb morphogenesis positive regulation of bone mineralization BMP signaling pathway epithelial cell differentiation negative regulation of NF-kappaB transcription factor activity response to estradiol response to vitamin D positive regulation of heterotypic cell-cell adhesion protein localization to nucleus growth negative regulation of phosphorylation negative regulation of NF-kappaB import into nucleus odontogenesis of dentin-containing tooth regulation of apoptotic process positive regulation of apoptotic process steroid hormone mediated signaling pathway negative regulation of MAP kinase activity response to peptide hormone negative regulation of neuron differentiation positive regulation of osteoblast differentiation negative regulation of Notch signaling pathway negative regulation of cell cycle negative regulation of mitotic nuclear division negative regulation of transcription, DNA-templated positive regulation of transcription, DNA-templated positive regulation of transcription from RNA polymerase II promoter embryonic camera-type eye morphogenesis branching morphogenesis of an epithelial tube mesenchymal cell differentiation neuron projection morphogenesis cartilage development embryonic skeletal joint morphogenesis regulation of pathway-restricted SMAD protein phosphorylation SMAD protein signal transduction branching involved in salivary gland morphogenesis mesenchyme development negative regulation of cell death negative regulation of prostatic bud formation regulation of branching involved in prostate gland morphogenesis monocyte aggregation cellular response to hypoxia cellular response to BMP stimulus negative regulation of mesenchymal cell apoptotic process involved in nephron morphogenesis negative regulation of glomerular mesangial cell proliferation metanephric mesenchyme morphogenesis nephrogenic mesenchyme morphogenesis metanephric mesenchymal cell proliferation involved in metanephros development positive regulation of dendrite development positive regulation of hyaluranon cable assembly regulation of removal of superoxide radicals eye development kidney development multicellular organism development pattern specification process salivary gland morphogenesis negative regulation of cell proliferation organ morphogenesis positive regulation of cell death cell differentiation tube morphogenesis regulation of phosphorylation regulation of MAPK cascade positive regulation of cell differentiation positive regulation of neuron differentiation cell development camera-type eye morphogenesis anatomical structure formation involved in morphogenesis negative regulation of neurogenesis