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BOK Antibody (PA5-106615) in ICC/IF
Immunocytochemistry analysis of BOK in A549 cells. The samples were fixed with PFA and permeabilized in 0.1% Triton X-100, then blocked in 10% serum for 45 minutes at 25°C. Samples were incubated with BOK polyclonal antibody (Product # PA5-106615) and mouse anti-beta tubulin antibody for 1 hour at 37°C. An AlexaFluor594 conjugated goat anti-rabbit IgG(H+L) (Red) and an AlexaFluor488 conjugated goat anti-mouse IgG(H+L) (Green) were used as the secondary antibodies. The nuclear counter stain is DAPI (blue).
产品信息
PA5-106615
应用
建议稀释比
已发表文章
产品规格
种属反应
Human,
Mouse,
Rat
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
A synthesized peptide derived from human BOK(Accession Q9UMX3), corresponding to amino acid residues M1-S49.
偶联物
形式
Liquid
浓度
1 mg/mL
纯化类型
Affinity chromatography
保存液
PBS, pH 7.4, with 50% glycerol
内含物
0.02% sodium azide
保存条件
-20°C
运输条件
Wet ice
RRID
AB_2854283
产品详细信息
Antibody detects endogenous levels of total BOK.
靶标信息
The protein encoded by this gene belongs to the BCL-2 protein family. BCL-2 family members form hetero- or homodimers and act as anti- and pro-apoptotic regulators that are involved in a wide variety of cellular activities. This protein contains all four BCL-2 like domains and is a pro-apoptotic BCL-2 protein identified in the ovary.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: Apoptosis activator Mtd; Bcl-2-like protein 9; Bcl-2-related ovarian killer protein; BCL2 related ovarian killer; Bcl2-L-9; BCL2-related ovarian killer; BCL2-related ovarian killer protein; hBOK; Protein matador
基因别名: AI847676; AU021146; BCL2L9; BOK; Bok-BH3; BOKL; matador; Mtd
UniProt ID: (Human) Q9UMX3, (Rat) Q792S6, (Mouse) O35425
Entrez Gene ID: (Human) 666, (Rat) 29884, (Mouse) 51800
apoptotic process
activation of cysteine-type endopeptidase activity involved in apoptotic process
brain development
cell proliferation
male gonad development
intrinsic apoptotic signaling pathway in response to DNA damage
positive regulation of apoptotic process
oligodendrocyte differentiation
neuron apoptotic process
intrinsic apoptotic signaling pathway by p53 class mediator
extrinsic apoptotic signaling pathway in absence of ligand
positive regulation of execution phase of apoptosis
regulation of apoptotic process
