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BRAF35 Antibody (PA5-27996) in ICC/IF
BRAF35 Polyclonal Antibody detects BRAF35 protein at nucleus by immunofluorescent analysis. Sample: A375 cells were fixed in 4% paraformaldehyde at RT for 15 min. Green: BRAF35 protein stained by BRAF35 Polyclonal Antibody (Product # PA5-27996) diluted at 1:500. Blue: Hoechst 33342 staining.
产品信息
PA5-27996
产品规格
种属反应
Human
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
Recombinant fragment corresponding to a region within amino acids 1 and 314 of Human BRAF35
偶联物
形式
Liquid
浓度
0.95 mg/mL
纯化类型
Antigen affinity chromatography
保存液
0.1M tris glycine, pH 7, with 10% glycerol
内含物
0.01% thimerosal
保存条件
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
运输条件
Wet ice
RRID
AB_2545472
产品详细信息
Recommended positive controls: 293T.
Predicted reactivity: Mouse (95%), Rat (94%), Bovine (98%).
Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.
靶标信息
Required for correct progression through G2 phase of the cell cycle and entry into mitosis. Required for RCOR1/CoREST mediated repression of neuronal specific gene promoters.
⚠WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm. For more information go to www.P65Warnings.ca.gov.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: 94 kDa B-raf protein; B-Raf proto-oncogene serine/threonine-protein kinase (p94); BRCA2-associated factor 35; FLJ26127; high-mobility group 20B; HMG box domain containing 2; HMG box-containing protein 20B; HMG domain-containing protein 2; HMG domain-containing protein HMGX2; murine sarcoma viral (v-raf) oncogene homolog B1; p94; Proto-oncogene B-Raf; Serine/threonine-protein kinase B-raf; SMARCE1-related protein; Sox-like transcriptional factor; Structural DNA-binding protein BRAF35; SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily E member 1-related; SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily E, member 1-related; v-raf murine sarcoma viral oncogene homolog B; v-Raf murine sarcoma viral oncogene homolog B1
基因别名: B-raf; B-RAF1; BRAF; BRAF1; BRAF25; BRAF35; HMG20B; HMGX2; HMGXB2; NS7; PP7706; pp8857; RAFB1; SMARCE1R; SOXL
UniProt ID: (Human) P15056, (Human) Q9Y491
Entrez Gene ID: (Human) 673, (Human) 10362
protein kinase activity
protein serine/threonine kinase activity
MAP kinase kinase kinase activity
calcium ion binding
protein binding
ATP binding
small GTPase binding
mitogen-activated protein kinase kinase binding
identical protein binding
protein heterodimerization activity
DNA binding
histone deacetylase activity
non-receptor serine/threonine protein kinase
MAPK cascade
activation of MAPKK activity
myeloid progenitor cell differentiation
protein phosphorylation
visual learning
organ morphogenesis
positive regulation of gene expression
negative regulation of fibroblast migration
glucose transport
thyroid gland development
positive regulation of peptidyl-serine phosphorylation
somatic stem cell population maintenance
cellular response to drug
regulation of cell proliferation
negative regulation of apoptotic process
CD4-positive, alpha-beta T cell differentiation
positive T cell selection
response to peptide hormone
negative regulation of neuron apoptotic process
thymus development
positive regulation of axon regeneration
positive regulation of axonogenesis
protein heterooligomerization
positive regulation of stress fiber assembly
response to cAMP
long-term synaptic potentiation
head morphogenesis
face development
positive regulation of ERK1 and ERK2 cascade
cellular response to calcium ion
establishment of protein localization to membrane
positive regulation of substrate adhesion-dependent cell spreading
negative regulation of synaptic vesicle exocytosis
negative regulation of endothelial cell apoptotic process
transcription, DNA-templated
regulation of transcription, DNA-templated
cell cycle
blood coagulation
histone deacetylation
negative regulation of protein sumoylation
skeletal muscle cell differentiation
positive regulation of neuron differentiation
