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Immunogen sequence: IRVSEKPSAD YVLSVRDTQA VRHYKIWRRA GGRLHLNEAV SFLSLPELVN YHRAQSLSHG LRLAAPCRKH EPEPLPHWDD WE
Breast tumor kinase (Brk) is a non-receptor protein tyrosine kinase expressed in over 60% of breast carcinoma tissue samples and breast tumor cell lines. Brk is 80% identity to Sik (Src-related intestinal kinase) and exhibits the features of a novel non-receptor tyrosine kinase, including amino terminal SH3 and SH2 domains. Low levels of Brk transcripts have been identified in some human breast tumor cell lines but not in normal breast tissue.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: ALT-PTK6; Breast tumor kinase; deltam5; FLJ42088; Protein-tyrosine kinase 6; protein-tyrosine kinase BRK; PTK6 protein tyrosine kinase 6; Tyrosine-protein kinase BRK
基因别名: BRK; PTK6
UniProt ID: (Human) Q13882
Entrez Gene ID: (Human) 5753
分子生物学功能:
protein-binding activity modulator
scaffold/adaptor protein