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产品信息
BAB-101AP
应用
建议稀释比
已发表文章
产品规格
种属反应
Fruit fly
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
N-epitope Synthetic peptide corresponding to amino acid region 200-221 of Drosophila melanogaster protein. The peptide was covalently modified for conjugation.Synthetic peptide:CNKNENMKRIFEDYVPHRLTS
偶联物
形式
Liquid
浓度
0.5-1.5 mg/mL
纯化类型
Affinity chromatography
保存液
proprietary buffer, pH 7.4-7.8, with 30% glycerol, 0.5% BSA
内含物
0.02% sodium azide
保存条件
-20°C
运输条件
Wet ice
靶标信息
Invovled in activin binding, GPCR kinase activity, serine threonine kinase activity and transforming growth factor beta receptor activity. The role of Baboon (Babo), a type I Activin receptor previously called Atr-I, in Drosophila development and characterize aspects of the Babo intracellular signal-transduction pathway. Genetic analysis of babo loss-of-function mutants and ectopic activation studies indicate that Babo signaling plays a role in regulating cell proliferation. In mammalian cells, activated Babo specifically stimulates Smad2-dependent pathways to induce TGF-beta/Activin-responsive promoters but not BMP-responsive elements.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: activin A receptor 45A; activin type I receptor; babo; babo-PA; babo-PB; babo-PC; baboa; CG8224; CG8224-PA; CG8224-PB; CG8224-PC; G protein-coupled receptor kinase 3; RE55648p; Receptor protein serine/threonine kinase
基因别名: Atf1; ATR-1; ATR-I; Atr45A; AtrI; Bab; BABO; Babo-a; BaboA; CG8224; Dmel\CG8224; Dmel_CG8224; Gprk-3; Gprk3; l(2)44Fd; l(2)k16912; STK-E
Entrez Gene ID: (Fruit fly) 35900
positive regulation of neuroblast proliferation
protein phosphorylation
nervous system development
axon guidance
eye-antennal disc morphogenesis
imaginal disc-derived wing morphogenesis
determination of adult lifespan
response to UV
negative regulation of autophagy
mushroom body development
activin receptor signaling pathway
glucose homeostasis
regulation of imaginal disc-derived wing size
R8 cell fate specification
positive regulation of imaginal disc growth
neuron development
dendrite morphogenesis
regulation of synapse structure or activity
pathway-restricted SMAD protein phosphorylation
SMAD protein signal transduction
cellular response to glucose stimulus
cellular response to growth factor stimulus
