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Bacillus anthracis Lethal Factor Antibody (MA1-22669) in ELISA
Calibration curve in ELISA for B. Anthracis Lethal Factor Antigen determination using (Product # MA1-22668) for coating and Bacillus anthracis Lethal Factor Monoclonal Antibody (BAL0106) (Product # MA1-22669) as a HRP conjugate.
产品信息
MA1-22669
产品规格
种属反应
Bacteria
宿主/亚型
Mouse
/ IgG1
分类
Monoclonal
类型
Antibody
克隆号
BAL0106
抗原
Highly purified lethal factor antigen of Bacillus anthracis.
偶联物
形式
Liquid
浓度
2 mg/mL
纯化类型
Protein G
保存液
PBS, pH 7.4
内含物
0.09% sodium azide
保存条件
4° C, do not freeze
运输条件
Ambient (domestic); Wet ice (international)
RRID
AB_557702
产品详细信息
MA1-22669 detects Bacillus anthracis lethal factor in Bacteria samples.
靶标信息
Anthrax toxin is a three-protein exotoxin secreted by virulent strains of the bacterium Bacillus anthracis, the causative agent of anthrax. Anthrax toxin is composed of a cell-binding protein, known as protective antigen (PA), and two enzyme components, called edema factor (EF) and lethal factor (LF). These three protein components act together to impart their physiological effects. Assembled complexes containing the toxin components are endocytosed. In the endosome, the enzymatic components of the toxin translocate into the cytoplasm of a target cell. Once in the cytosol, the enzymatic components of the toxin disrupts various immune cell functions, namely cellular signaling and cell migration. The toxin may even induce cell lysis, as is observed for macrophage cells. Anthrax toxin allows the bacteria to evade the immune system, proliferate, and ultimately kill the host animal. Research on anthrax toxin also provides insight into the generation of macromolecular assemblies, and on protein translocation, pore formation, endocytosis, and other biochemical processes.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: Anthrax LF; B. anthracis LF
