Product References
MiRNA-106a-5p Promotes Laryngeal Carcinoma Proliferation and Migration Through PI3K/AKT/m-TOR Pathway by AKTIP.
Iranian journal of biotechnology
Gong L,Wang XF,Liu H,Li L
14-6997-82 was used in Western Blotting to uncover a new mechanism, that miR-106a-5p promotes LC development via AKTIP/PI3K/AKT/m-TOR axis, which guides clinical management and drug discovery.
Sun Jan 01 00:00:00 EST 2023
Protective Effect of Photobiomodulation against Hydrogen Peroxide-Induced Oxidative Damage by Promoting Autophagy through Inhibition of PI3K/AKT/mTOR Pathway in MC3T3-E1 Cells.
Oxidative medicine and cellular longevity
Zuo X,Wei X,Ju C,Wang X,Zhang Z,Ma Y,Zhu Z,Li X,Song Z,Luo L,Hu X,Wang Z
Published figure using Bax monoclonal antibody (Product # 14-6997-82) in Western Blot
Mon Dec 05 00:00:00 EST 2022
Multinucleated polyploid cardiomyocytes undergo an enhanced adaptability to hypoxia via mitophagy.
Journal of molecular and cellular cardiology
Jiang YH,Wang HL,Peng J,Zhu Y,Zhang HG,Tang FQ,Jian Z,Xiao YB
14-6997 was used in Western Blotting to determine the pathophysiological significance of increased multinucleated polyploid cardiomyocytes during hypoxia adaptation.
Wed Jan 01 00:00:00 EST 2020
The Cytoplasmic DNA Sensor cGAS Promotes Mitotic Cell Death.
Cell
Zierhut C,Yamaguchi N,Paredes M,Luo JD,Carroll T,Funabiki H
14-6997 was used in Immunocytochemistry-Immunofluorescence to study the role of cGAS and IRF3 in triggering mitotic cell death.
Thu Jul 11 00:00:00 EDT 2019
Therapeutic effect of Sirtuin 3 on ameliorating nonalcoholic fatty liver disease: The role of the ERK-CREB pathway and Bnip3-mediated mitophagy.
Redox biology
Li R,Xin T,Li D,Wang C,Zhu H,Zhou H
Published figure using Bax monoclonal antibody (Product # 14-6997-82) in Western Blot
Sat Sep 01 00:00:00 EDT 2018
Mammalian STE20-Like Kinase 1 Deletion Alleviates Renal Ischaemia-Reperfusion Injury via Modulating Mitophagy and the AMPK-YAP Signalling Pathway.
Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology
Feng J,Li H,Zhang Y,Wang Q,Zhao S,Meng P,Li J
14-6997 was used in Western Blotting to demonstrate that the pathogenesis of renal ischaemia-reperfusion injury is closely associated with an increase in Mst1 expression and the inactive AMPK-YAP-OPA1 signalling pathway.
Fri Jan 25 00:00:00 EST 2019
Removal of syndecan-1 promotes TRAIL-induced apoptosis in myeloma cells.
Journal of immunology (Baltimore, Md. : 1950)
Wu YH,Yang CY,Chien WL,Lin KI,Lai MZ
14-6997 was used in Western Blotting to investigate whether removal of syndecan-1 promotes apoptotic processes.
Thu Mar 15 00:00:00 EDT 2012
Dampening of death pathways by schnurri-2 is essential for T-cell development.
Nature
Staton TL,Lazarevic V,Jones DC,Lanser AJ,Takagi T,Ishii S,Glimcher LH
14-6997 was used in Immunoprecipitation to assess the role of schnurri-2 in T-cell development.
Thu Apr 07 00:00:00 EDT 2011
Identification of Bax-voltage-dependent anion channel 1 complexes in digitonin-solubilized cerebellar granule neurons.
Journal of neurochemistry
Huckabee DB,Jekabsons MB
14-6997 was used in Immunoprecipitation to assess the usefulness of different detergents to assess the oligomeric state and ability of Bax to interact with ion channels in neurones.
Thu Dec 01 00:00:00 EST 2011
RUNX3 modulates DNA damage-mediated phosphorylation of tumor suppressor p53 at Ser-15 and acts as a co-activator for p53.
The Journal of biological chemistry
Yamada C,Ozaki T,Ando K,Suenaga Y,Inoue K,Ito Y,Okoshi R,Kageyama H,Kimura H,Miyazaki M,Nakagawara A
14-6997 was used in Western Blotting to identify target residues on p53 phosphorylated by RUNX3 and assess the role of this in DNA damage responses.
Fri May 28 00:00:00 EDT 2010
RUNX3 modulates DNA damage-mediated phosphorylation of tumor suppressor p53 at Ser-15 and acts as a co-activator for p53.
The Journal of biological chemistry
Yamada C,Ozaki T,Ando K,Suenaga Y,Inoue K,Ito Y,Okoshi R,Kageyama H,Kimura H,Miyazaki M,Nakagawara A
14-6997 was used in Western Blotting to identify target residues on p53 phosphorylated by RUNX3 and assess the role of this in DNA damage responses.
Fri May 28 00:00:00 EDT 2010
Caspase inhibition blocks cell death and results in cell cycle arrest in cytokine-deprived hematopoietic cells.
The Journal of biological chemistry
Brown NM,Martin SM,Maurice N,Kuwana T,Knudson CM
14-6997 was used in Flow cytometry/Cell sorting to investigate the effect of caspase inhibition in cytokine-deprived hematopoietic cells.
Fri Jan 26 00:00:00 EST 2007
Caspase inhibition blocks cell death and results in cell cycle arrest in cytokine-deprived hematopoietic cells.
The Journal of biological chemistry
Brown NM,Martin SM,Maurice N,Kuwana T,Knudson CM
14-6997 was used in Flow cytometry/Cell sorting to investigate the effect of caspase inhibition in cytokine-deprived hematopoietic cells.
Fri Jan 26 00:00:00 EST 2007
Stabilization of p73 by nuclear IkappaB kinase-alpha mediates cisplatin-induced apoptosis.
The Journal of biological chemistry
Furuya K,Ozaki T,Hanamoto T,Hosoda M,Hayashi S,Barker PA,Takano K,Matsumoto M,Nakagawara A
14-6997 was used in Western Blotting to investigate the role of p73 and p52 in apoptosis.
Fri Jun 22 00:00:00 EDT 2007
Taurine monochloramine activates a cell death pathway involving Bax and Caspase-9.
The Journal of biological chemistry
Emerson DK,McCormick ML,Schmidt JA,Knudson CM
14-6997 was used in Flow cytometry/Cell sorting to study the ability of taurine monochloramine to trigger apoptosis through an interaction with BAX.
Fri Feb 04 00:00:00 EST 2005