Bcl-2 Monoclonal Antibody (8E12)

protease binding protein binding transcription factor binding channel activity channel inhibitor activity ubiquitin protein ligase binding identical protein binding protein homodimerization activity sequence-specific DNA binding protein heterodimerization activity BH3 domain binding protein phosphatase 2A binding protein phosphatase binding BH domain binding

protein polyubiquitination ossification ovarian follicle development metanephros development branching involved in ureteric bud morphogenesis behavioral fear response B cell homeostasis release of cytochrome c from mitochondria regulation of cell-matrix adhesion lymphoid progenitor cell differentiation B cell lineage commitment response to ischemia renal system process protein dephosphorylation melanin metabolic process regulation of nitrogen utilization apoptotic process humoral immune response cellular response to DNA damage stimulus actin filament organization axonogenesis female pregnancy cell aging male gonad development extrinsic apoptotic signaling pathway via death domain receptors intrinsic apoptotic signaling pathway in response to DNA damage intrinsic apoptotic signaling pathway in response to oxidative stress response to radiation response to toxic substance post-embryonic development response to iron ion response to UV-B response to gamma radiation regulation of gene expression negative regulation of autophagy negative regulation of calcium ion transport into cytosol regulation of glycoprotein biosynthetic process mesenchymal cell development positive regulation of neuron maturation positive regulation of smooth muscle cell migration cell growth peptidyl-serine phosphorylation peptidyl-threonine phosphorylation cochlear nucleus development gland morphogenesis regulation of transmembrane transporter activity negative regulation of ossification positive regulation of cell growth negative regulation of cell growth melanocyte differentiation negative regulation of cell migration positive regulation of B cell proliferation hair follicle morphogenesis axon regeneration regulation of protein stability endoplasmic reticulum calcium ion homeostasis glomerulus development negative regulation of cellular pH reduction negative regulation of myeloid cell apoptotic process T cell differentiation in thymus positive regulation of peptidyl-serine phosphorylation negative regulation of osteoblast proliferation response to cytokine response to nicotine organ growth positive regulation of multicellular organism growth B cell proliferation cellular response to glucose starvation response to drug response to hydrogen peroxide T cell homeostasis negative regulation of apoptotic process positive regulation of catalytic activity CD8-positive, alpha-beta T cell lineage commitment regulation of protein homodimerization activity regulation of protein heterodimerization activity negative regulation of neuron apoptotic process ear development regulation of viral genome replication positive regulation of melanocyte differentiation negative regulation of retinal cell programmed cell death regulation of mitochondrial membrane permeability focal adhesion assembly spleen development thymus development digestive tract morphogenesis oocyte development positive regulation of skeletal muscle fiber development pigment granule organization homeostasis of number of cells within a tissue B cell receptor signaling pathway response to glucocorticoid neuron apoptotic process defense response to virus regulation of mitochondrial membrane potential negative regulation of mitochondrial depolarization regulation of calcium ion transport transmembrane transport intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress cellular response to organic substance cellular response to hypoxia reactive oxygen species metabolic process extrinsic apoptotic signaling pathway in absence of ligand positive regulation of protein insertion into mitochondrial membrane involved in apoptotic signaling pathway negative regulation of G1/S transition of mitotic cell cycle negative regulation of reactive oxygen species metabolic process negative regulation of anoikis negative regulation of apoptotic signaling pathway negative regulation of extrinsic apoptotic signaling pathway in absence of ligand negative regulation of intrinsic apoptotic signaling pathway positive regulation of intrinsic apoptotic signaling pathway cell morphogenesis response to acid chemical ureteric bud development leukocyte homeostasis kidney development lymphocyte homeostasis T cell lineage commitment immune system development cellular calcium ion homeostasis response to oxidative stress cell proliferation positive regulation of cell proliferation negative regulation of cell proliferation apoptotic mitochondrial changes organ morphogenesis single organismal cell-cell adhesion hemopoiesis B cell differentiation T cell differentiation regulation of protein localization growth regulation of apoptotic process regulation of programmed cell death pigmentation negative regulation of mitotic cell cycle developmental pigmentation regulation of developmental pigmentation positive regulation of developmental pigmentation response to steroid hormone developmental growth regulation of catalytic activity regulation of cell cycle