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Product may be used with Western Blot (Transfected lysate).
The Isotype of this product is composed of an IgG Mixture.
Immunogen sequence: MKVEKDHLAK PFFPAIYKEF EELHKLVKKM CQDYLSSSGL CSQETLEINN DKVAESLGIT EFLRKKEIHP DNLGPKHLSR DMDGEQLEGA SSEKREREAA EEGLASVKRP RREALSNDTT ESLAANSRGR EKPRPLHALA AGEGFSPPVN VTVSPRSEES HTTTVSGGNG SVFQAGPQLQ ALANLEARRG SIGAALSSRD VSGLPVYAQS GEPRRLTQAQ VAAFPGENAL EHSSDQDTWD SLRSPGFCSP LSSGGGAESL PPGGPGHAEA GHLGKVCDFH LNHQQPSPTS VLPTEVAAPP LEKILSVDSV AVDCAYRTVP KPGPQPGPHG SLLTEGCLRS LSGDLNRFPC GMEVHSGQRE LESVVAVGEA MAFEISNGSH ELLSQGQKQI FIQTSDGLIL SPPGTIVSQE EDIVTVTDAE GRACGWAR
ZNF839, also known as C14orf131, is an 811 amino acid protein that contains one C2H2-type zinc finger. The gene encoding ZNF839 localizes to chromosome 14 and, due to alternative splicing events, four ZNF839 isoforms are expressed. Chromosome 14 contains about 700 genes and 106 million base pairs and makes up about 3.5% of human cellular DNA. Chromosome 14 encodes the presinilin 1 (PSEN1) gene, which is one of the three key genes associated with the development of Alzheimer's disease. The SERPINA1 gene is located on chromosome 14 and when defective leads to the genetic disorder alpha1-antitrypsin deficiency. This disorder is characterized by severe lung complications and liver dysfunction. Notably, the immunoglobulin heavy chain locus is found on chromosome 14 and has been identified as a fusion with the chromosome 19 encoded protein BCL3 in the (14; 19) translocations found in a variety of B cell malignancies.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: Renal carcinoma antigen NY-REN-50; Zinc finger protein 839
基因别名: C14orf131; ZNF839
UniProt ID: (Human) Q6GPI5
Entrez Gene ID: (Human) 55778