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产品信息
PA5-55929
应用
建议稀释比
已发表文章
产品规格
种属反应
Human
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
偶联物
形式
Liquid
浓度
0.1 mg/mL
纯化类型
Antigen affinity chromatography
保存液
PBS, pH 7.2, with 40% glycerol
内含物
0.02% sodium azide
保存条件
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
运输条件
Wet ice
RRID
AB_2638948
产品详细信息
Immunogen sequence: GRGRGMIGRG RGGFGGRGRG RGRGRGALAR PVLTKEQLDN QLDAYMSKTK GHLDAELDAY MAQTDPETND
Highest antigen sequence identity to the following orthologs: Mouse - 99%, Rat - 99%.
靶标信息
CHTOP is a small nuclear protein that is characterized by an arginine and glycine rich region. This protein may have an important role in the regulation of fetal globin gene expression and in the activation of estrogen-responsive genes. A recent study reported that this protein binds 5-hydroxymethylcytosine (5hmC) and associates with an arginine methyltransferase complex (methylosome), which promotes methylation of arginine 3 of histone H4 (H4R3) and activation of genes involved in glioblastomagenesis. Alternatively spliced transcript variants encoding different isoforms have been described for this gene.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: Chromatin target of PRMT1 protein; DKFZP547E1010; Friend of Prmt1; Friend of PRMT1 protein; RP1-178F15.2; Small arginine- and glycine-rich protein; small protein rich in arginine and glycine; SRAG
基因别名: C1orf77; CHTOP; FL-SRAG; FOP; HT031; PP7704; SRAG; SRAG-3; SRAG-5
UniProt ID: (Human) Q9Y3Y2
Entrez Gene ID: (Human) 26097
regulation of transcription, DNA-templated
termination of RNA polymerase II transcription
RNA export from nucleus
mRNA export from nucleus
positive regulation of cell proliferation
positive regulation of histone methylation
mRNA 3'-end processing
positive regulation of ATPase activity
positive regulation of helicase activity
