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产品信息
AAR-036-F-50UL
产品规格
种属反应
Mouse,
Rat
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
Peptide EPRKPQKSGIMKQQR, corresponding to amino acid residues 960-974 of mouse GPR158. Intracellular, C-terminus.
偶联物
激发/发射光谱
498/517 nm
查看光谱
形式
Lyophilized
浓度
1 mg/mL
纯化类型
Antigen affinity chromatography
保存液
PBS, pH 7.4, with 1% BSA
内含物
0.05% sodium azide
保存条件
-20° C, Avoid Freeze/Thaw Cycles
运输条件
Ambient (domestic); Wet ice (international)
产品详细信息
Immunogen sequence: EPRKPQKSGIMKQQR
Reconstitution: 25 uL, 50 uL or 0.2 mL double distilled water (DDW), depending on the sample size. The antibody ships as a lyophilized powder at room temperature. Upon arrival, it should be stored at -20C. The reconstituted solution can be stored at 4C for up to 1 week. For longer periods, small aliquots should be stored at -20C. Avoid multiple freezing and thawing. Centrifuge all antibody preparations before use (10000 x g 5 min).
靶标信息
C3AR1 is a receptor for the chemotactic and inflammatory peptide anaphylatoxin C3a. The receptor stimulates chemotaxis, granule enzyme release and superoxide anion production. (Uniprot)
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: anaphylatoxin C3a receptor; C3a anaphylatoxin chemotactic receptor; C3a receptor; C3a-R; C3AR; Complement component 3a receptor 1
基因别名: AZ3B; C3AR; C3ar1; C3r1; HNFAG09
UniProt ID: (Rat) O55197, (Mouse) O09047
Entrez Gene ID: (Rat) 84007, (Mouse) 12267
complement receptor mediated signaling pathway
tolerance induction to nonself antigen
chemotaxis
G-protein coupled receptor signaling pathway
positive regulation of cytosolic calcium ion concentration
regulation of blood pressure
positive regulation of vascular endothelial growth factor production
positive regulation of macrophage chemotaxis
positive regulation of cell migration
positive regulation of angiogenesis
positive regulation of smooth muscle cell proliferation
positive regulation of glomerular mesangial cell proliferation
positive regulation of neutrophil chemotaxis
positive regulation of DNA biosynthetic process
signal transduction
