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产品信息
PA5-76320
应用
建议稀释比
已发表文章
产品规格
种属反应
Human,
Mouse
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
Recombinant protein of human CALCOCO1.
偶联物
形式
Liquid
浓度
1 mg/mL
纯化类型
Antigen affinity chromatography
保存液
PBS, pH 7.2, with 50% glycerol
内含物
0.02% sodium azide
保存条件
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
运输条件
Wet ice
RRID
AB_2720047
产品详细信息
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
靶标信息
CALCOCO1 (calcium-binding and coiled-coil domain-containing protein 1), also known as cocoa, calphoglin, sarcoma antigen NY-SAR-3 or coiled-coil coactivator protein, is a 691 amino acid protein that shuttles between the cytoplasm and nucleus and functions as coactivator for aryl hydrocarbon and nuclear receptors. A member of the CALCOCO family, CALCOCO1 is forms a calphoglin complex with PPA1 and PGM 1 and contains multiple functional domains through which it acts as a component of both the androgen signaling pathway and the Wnt/beta-catenin signaling pathway.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: Calcium-binding and coiled-coil domain-containing protein 1; Calphoglin; Coiled-coil coactivator protein; coiled-coil leucine zipper coactivator 1; coiled-coil transcriptional coactivator; granule cell antiserum positive 11; GRIP1-interacting protein; inorganic pyrophosphatase activator; Sarcoma antigen NY-SAR-3
基因别名: 1810009B06Rik; CALCOCO1; calphoglin; CocoA; Gcap11; KIAA1536; mKIAA1536; PP13275; UNQ2436/PRO4996
UniProt ID: (Human) Q9P1Z2, (Mouse) Q8CGU1
Entrez Gene ID: (Human) 57658, (Mouse) 67488
core promoter binding
chromatin binding
transcription cofactor activity
transcription coactivator activity
protein binding
beta-catenin binding
protein C-terminus binding
ligand-dependent nuclear receptor transcription coactivator activity
sequence-specific DNA binding
transcription regulatory region DNA binding
armadillo repeat domain binding
transcription, DNA-templated
signal transduction
positive regulation of gene expression
Wnt signaling pathway
intracellular steroid hormone receptor signaling pathway
positive regulation of transcription, DNA-templated
positive regulation of transcription from RNA polymerase II promoter
regulation of nucleic acid-templated transcription
