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产品信息
H00008536-M01
产品规格
种属反应
Human
宿主/亚型
Mouse
/ IgG1, kappa
分类
Monoclonal
类型
Antibody
克隆号
3G1
抗原
CAMK1 (NP_003647, 271 a.a. approximately 370 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
偶联物
形式
Liquid
浓度
0.5 mg/mL
纯化类型
Protein A
保存液
PBS, pH 7.4
内含物
no preservative
保存条件
-20° C, Avoid Freeze/Thaw Cycles
运输条件
Ambient (domestic); Wet ice (international)
产品详细信息
Product may be used with Western Blot (Cell lysate).
Immunogen sequence: LQHPWIAGDT ALDKNIHQSV SEQIKKNFAK SKWKQAFNAT AVVRHMRKLQ LGTSQEGQGQ TASHGELLTP VAGGPAAGCC CRDCCVEPGT ELSPTLPHQL
靶标信息
CAMK1 (CaMK1) is a serine/threonine kinase that is a member of the calcium/calmodulin-dependent protein kinase family. It is involved in cell differentiation, nervous system development, and signal transduction. CAMK1 is expressed in many tissues and is a component of a calmodulin-dependent protein kinase cascade. Calcium/calmodulin directly activates calcium/calmodulin-dependent protein kinase I by binding to the enzyme and indirectly promotes the phosphorylation and synergistic activation of the enzyme by calcium/calmodulin-dependent protein kinase I kinase.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: calcium/calmodulin-dependent protein kinase I; Calcium/calmodulin-dependent protein kinase type 1; CaM kinase I; CaM kinase I alpha; CaM-KI; CAMK1-PEN; CaMKI-alpha; MGC120317; MGC120318
基因别名: CAMK1; CAMKI
UniProt ID: (Human) Q14012
Entrez Gene ID: (Human) 8536
protein phosphorylation
nucleocytoplasmic transport
cell cycle
signal transduction
positive regulation of neuron projection development
negative regulation of protein binding
regulation of protein localization
positive regulation of peptidyl-serine phosphorylation
regulation of protein binding
positive regulation of transcription from RNA polymerase II promoter
positive regulation of protein export from nucleus
regulation of muscle cell differentiation
positive regulation of muscle cell differentiation
positive regulation of synapse structural plasticity
positive regulation of syncytium formation by plasma membrane fusion
positive regulation of dendritic spine development
positive regulation of protein serine/threonine kinase activity
positive regulation of protein acetylation
regulation of histone H3-K9 acetylation
