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CARKL Antibody (PA5-55063) in IHC
Immunohistochemical staining of CARKL in human kidney and pancreas tissues using CARKL Polyclonal Antibody (Product # PA5-55063). Corresponding SHPK RNA-seq data are presented for the same tissues.
产品信息
PA5-55063
产品规格
种属反应
Human
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
偶联物
Unconjugated
形式
Liquid
浓度
0.05 mg/mL
纯化类型
Antigen affinity chromatography
保存液
PBS, pH 7.2, with 40% glycerol
内含物
0.02% sodium azide
保存条件
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
运输条件
Wet ice
RRID
AB_2639293
产品详细信息
Immunogen sequence: FLKSYDAAGT IHDYVVAMLC GLPRPLMSDQ NAASWGYFNT QSQSWNVETL RSSGFPVHLL PDIAEPGSVA GRTSHMWFEI PKGTQV
Highest antigen sequence identity to the following orthologs: Mouse - 90%, Rat - 85%.
靶标信息
The protein encoded by this gene has weak homology to several carbohydrate kinases, a class of proteins involved in the phosphorylation of sugars as they enter a cell, inhibiting return across the cell membrane. Sequence variation between this novel gene and known carbohydrate kinases suggests the possibility of a different substrate, cofactor or changes in kinetic properties distinguishing it from other carbohydrate kinases. The gene resides in a region commonly deleted in cystinosis patients, suggesting a role as a modifier for the cystinosis phenotype. The genomic region is also rich in Alu repetitive sequences, frequently involved in chromosomal rearrangements.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: Carbohydrate kinase-like protein; Sedoheptulokinase; SHK
基因别名: CARKL; SHK; SHPK
UniProt ID: (Human) Q9UHJ6
Entrez Gene ID: (Human) 23729
