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CARMIL Antibody (A304-556A) in WB
Detection of human CARMIL by western blot. Samples: Whole cell lysate (50 µg) from HeLa, HEK293T, and Jurkat cells prepared using NETN lysis buffer. Antibodies: Affinity purified rabbit anti-CARMIL antibody (Product # A304-556A) (lot A304-556A-1) used for WB at 0.1 µg/mL. Detection: Chemiluminescence with an exposure time of 3 minutes.
产品信息
A304-556A
产品规格
种属反应
Human
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
Region between residue 1321 to 1371 of human Capping Protein, Arp2/3 and Myosin I Linker.
偶联物
形式
Liquid
浓度
1 mg/mL
纯化类型
Antigen affinity chromatography
保存液
phosphate/tris citrate, pH 7-8
内含物
0.09% sodium azide
保存条件
4° C
运输条件
Wet ice
产品详细信息
The recommended shelf life for this product is 1 year from date of receipt.
Based on 100% sequence identity, this antibody is predicted to react with Mouse
靶标信息
Cell membrane-cytoskeleton-associated protein that plays a role in the regulation of actin polymerization at the barbed end of actin filaments. Prevents F-actin heterodimeric capping protein (CP) activity at the leading edges of migrating cells, and hence generates uncapped barbed ends and enhances actin polymerization, however, seems unable to nucleate filaments (PubMed:16054028). Plays a role in lamellipodial protrusion formations and cell migration (PubMed:19846667). [UniProt]
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: Capping protein regulator and myosin 1 linker protein 1; Capping protein, Arp2/3 and myosin-I linker homolog 1; Capping protein, Arp2/3 and myosin-I linker protein 1; capping protein, Arp2/3, and Myosin-I Linker homolog 1; CARMIL homolog; F-actin-uncapping protein LRRC16A; leucine rich repeat containing 16; leucine rich repeat containing 16A; Leucine-rich repeat-containing protein 16A; testicular tissue protein Li 107
基因别名: CARMIL; CARMIL1; CARMIL1a; dJ501N12.1; dJ501N12.5; LRRC16; LRRC16A
UniProt ID: (Human) Q5VZK9
Entrez Gene ID: (Human) 55604
actin filament organization
blood coagulation
cell migration
lamellipodium assembly
positive regulation of cell migration
positive regulation of actin filament polymerization
ruffle organization
macropinocytosis
urate metabolic process
positive regulation of stress fiber assembly
barbed-end actin filament uncapping
actin filament network formation
positive regulation of substrate adhesion-dependent cell spreading
positive regulation of lamellipodium organization
negative regulation of barbed-end actin filament capping
