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The protein encoded by this gene is localized to the nucleus of endothelial cells and is induced by IL-1 and TNF-alpha stimulation. Studies in rat cardiomyocytes suggest that this gene functions as a transcription factor. Interactions between this protein and the sarcomeric proteins myopalladin and titin suggest that it may also be involved in the myofibrillar stretch-sensor system.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: ankyrin repeat domain 1 (cardiac muscle); Ankyrin repeat domain-containing protein 1; Cardiac ankyrin repeat protein; Cytokine-inducible gene C-193 protein; Cytokine-inducible nuclear protein; liver ankyrin repeat domain 1
基因别名: ALRP; ANKRD1; bA320F15.2; C-193; C193; CARP; CVARP; HA1A2; MCARP
UniProt ID: (Human) Q15327
Entrez Gene ID: (Human) 27063