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Product may be used with Western Blot (Transfected lysate).
The Isotype of this product is composed of an IgG Mixture.
Immunogen sequence: MPASRLRDRA ASSASGSTCG SMSQTHPVLE SGLLASAGCS APRGPRKGGP APVDRKAKAS AMPDSPAEVK TQPRSTPPSM PPPPPAASQG ATRPPSFTPH TLMNGSSHSP TAINGAPCTP NGFSNGPATS STASLSTQHL PPACGARQLS KLKRFLTTLQ QFGSDISPEI GERVRTLVLG LVNSTLTIEE FHSKLQEATN FPLRPFVIPF LKANLPLLQR ELLHCARLAK QTPAQYLAQH EQLLLDASAS SPIDSSELLL EVNENGKRRT PDRTKENGSD RDPLHPQRYS PSNGPPQPTP PPHYRLEDIA MAHHFRDAYR HPDPRELRER HRPLVVPGSR QEEVIDHKLT EREWAEEWKH LNNLLNCIMD MVEKTRRSLT VLRRCQEADR EELNHWARRY SDAEDTKKGP APAAARPRSS SAGPEGPQLD VPREFLPRTL TGYVPEDIWR KAEEAVNEVK RQAMSELQKA VSDAERKAHE LITTERAKME RALAEAKRQA SEDALTVINQ QEDSSESCWN CGRKASETCS GCNAARYCGS FCQHRDWEKH HHVCGQSLQG PTAVVADPVP GPPEAAHSLG PSLPVGAASP SEAGSAGPSR PGSPSPPGPL DTVPR
This gene encodes a member of the myeloid translocation gene family which interact with DNA-bound transcription factors and recruit a range of corepressors to facilitate transcriptional repression. The t(16;21)(q24;q22) translocation is one of the less common karyotypic abnormalities in acute myeloid leukemia. The translocation produces a chimeric gene made up of the 5'-region of the runt-related transcription factor 1 gene fused to the 3'-region of this gene. This gene is also a putative breast tumor suppressor. Alternative splicing results in transcript variants.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: core-binding factor, runt domain, alpha subunit 2; translocated to, 3; hMTG16; MTG16HEL; MTG8-related gene 2; MTG8-related protein 2; myeloid translocation gene 8 and 16b; Myeloid translocation gene on chromosome 16 protein; Protein CBFA2T3; Zinc finger MYND domain-containing protein 4
基因别名: CBFA2T3; ETO2; MTG16; MTGR2; RUNX1T3; ZMYND4
UniProt ID: (Human) O75081
Entrez Gene ID: (Human) 863
分子生物学功能: transcription cofactor