Invitrogen

CD155 Polyclonal Antibody

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CD155 Antibody (PA5-96414) in WB

Western blot analysis of CD155 in various lysates. Samples were incubated with CD155 Polyclonal antibody (Product # PA5-96414) using a dilution of 1:400, followed by HRP Goat Anti-Rabbit IgG (H+L) at a dilution of 1:10,000. Lysates/proteins: 25 µg per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit. Exposure time: 180s.

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产品信息

PA5-96414

应用

建议稀释比

已发表文章

免疫印迹 (WB)

1:100-1:500

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酶联免疫吸附实验 (ELISA)

1 µg/mL

产品规格

种属反应

Human, Mouse

已发表种属

Human

宿主/亚型

Rabbit / IgG

分类

Polyclonal

类型

Antibody

抗原

Recombinant fusion protein containing a sequence corresponding to amino acids 220-345 of human CD155/PVR (NP_0064964?)

查看免疫原

偶联物

Unconjugated Unconjugated Unconjugated

形式

Liquid

浓度

3.82 mg/mL

纯化类型

Affinity Chromatography

保存液

PBS, pH 7.3, with 50% glycerol

内含物

0.09% sodium azide

保存条件

-20° C, Avoid Freeze/Thaw Cycles

运输条件

Wet ice

RRID

AB_2808216

产品详细信息

Positive Samples: LO2; Cellular Location: Cell membrane, Single-pass type I membrane protein

Immunogen sequence: TCKVEHESFE KPQLLTVNLT VYYPPEVSIS GYDNNWYLGQ NEATLTCDAR SNPEPTGYNW STTMGPLPPF AVAQGAQLLI RPVDKPINTT LICNVTNALG ARQAELTVQV KEGPPSEHSG MSRNAI

靶标信息

The protein encoded by this gene is a transmembrane glycoprotein belonging to the immunoglobulin superfamily. The external domain mediates cell attachment to the extracellular matrix molecule vitronectin, while its intracellular domain interacts with the dynein light chain Tctex-1/DYNLT1. The gene is specific to the primate lineage, and serves as a cellular receptor for poliovirus in the first step of poliovirus replication. Multiple transcript variants encoding different isoforms have been found for this gene.

仅用于科研。不用于诊断过程。未经明确授权不得转售。

Product References

Tumor Cell-Intrinsic CD96 Mediates Chemoresistance and Cancer Stemness by Regulating Mitochondrial Fatty Acid β-Oxidation.

Advanced science (Weinheim, Baden-Wurttemberg, Germany)

Li J,Xia Q,Di C,Li C,Si H,Zhou B,Yu S,Li Y,Huang J,Lu Y,Huang M,Liang H,Liu X,Zhao Q

PA5-96414 was used in Western Blot to show that CD96 is frequently expressed in tumor cells from clinical breast cancer samples and is correlated with poor long-term prognosis in these patients.