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May be stored for twelve months without detectable loss of activity. Protect from prolonged exposure to light and do not freeze. Sodium azide is toxic to cells and should be disposed of properly so flush with large volumes of water during disposal.
SIGLEC5 is a putative adhesion molecule that mediates sialic-acid dependent binding to cells. This protein binds equally to alpha2,3-linked and alpha2,6-linked sialic acid. The sialic acid recognition site may be masked by cis interactions with sialic acids on the same cell surface. This molecule is expressed by monocytic/myeloid lineage cells. SIGLEC5 is found at high levels in peripheral blood leukocytes, spleen, bone marrow and at lower levels in lymph node, lung, appendix, placenta, pancreas and thymus. It is expressed by monocytes and neutrophils but absent from leukemic cell lines representing early stages of myelomonocytic differentiation.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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蛋白别名: CD170; CD33 antigen-like 2; OB-binding protein 2; OB-BP2; Obesity-binding protein 2; sialic acid binding Ig-like lectin 5; Sialic acid-binding Ig-like lectin 5; sialic acid-binding immunoglobulin-like lectin 5; Siglec; Siglec-5
基因别名: CD170; CD33L2; OB-BP2; OBBP2; SIGLEC-5; SIGLEC5
UniProt ID: (Human) O15389
Entrez Gene ID: (Human) 8778