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CD177 Antibody (MA5-18129) in Flow
Separation of CD177 positive neutrophil granulocytes (red-filled) from CD177 negative lymphocytes (black-dashed) in flow cytometry analysis (surface staining) of human peripheral whole blood stained using anti-human CD177 (MEM-166) Alexa Fluor® 647 Monoclonal antibody (Product # MA5-18129) using a dilution of 4 µL reagent/100 µL of peripheral whole blood.
产品信息
MA5-18129
产品规格
种属反应
Human,
Non-human primate
宿主/亚型
Mouse
/ IgG1
分类
Monoclonal
类型
Antibody
克隆号
MEM-166
抗原
Human granulocytes
偶联物
激发/发射光谱
650/671 nm
查看光谱
形式
Liquid
纯化类型
Size-exclusion chromatography
保存液
PBS with 0.2% BSA
内含物
15mM sodium azide
保存条件
4° C, store in dark, DO NOT FREEZE!
运输条件
Ambient (domestic); Wet ice (international)
RRID
AB_2539503
产品详细信息
This antibody reacts with CD177 (Neutrophil specific antigen 1), a 60 kDa GPI-linked cell surface glycoprotein of uPAR family, expressed on granulocytes and in bone marrow early erythroblasts, megakaryocytes, promyelocytes and myelocytes.
靶标信息
CD177 (NB1/HNA-2a and PRV-1 form) is a GPI-anchored glycoprotein present mainly on neutrophils. Its plasma membrane expression is increased during pregnancy and and inflammation or after G-CSF application. Ligand of CD177 has been identified as CD31 (PECAM-1). CD177 participates in neutrophil transmigration and seems to be also a pro-proliferative molecule. The antibodies against CD177 can be involved in neonatal alloimmune neutropenia (NAN).
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: CD177; CD177 antigen; cell surface receptor; HNA-2a; Human neutrophil alloantigen 2a; NB1 glycoprotein; NB1 GP; Polycythemia rubra vera protein 1; PRV-1
基因别名: CD177; HNA-2a; HNA2A; NB1; NB1 GP; PRV-1; PRV1; UNQ595/PRO1181
UniProt ID: (Human) Q8N6Q3
Entrez Gene ID: (Human) 57126
