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产品信息
PA5-20013
产品规格
种属反应
Human,
Mouse,
Rat
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
A synthetic peptide corresponding to amino acids near the carboxy terminus of human BAFF Receptor
偶联物
形式
Liquid
浓度
1 mg/mL
纯化类型
Antigen affinity chromatography
保存液
PBS
内含物
0.02% sodium azide
保存条件
Maintain refrigerated at 2-8°C for up to 3 months. For long term storage store at -20°C
运输条件
Ambient (domestic); Wet ice (international)
RRID
AB_11157880
产品详细信息
A suggested positive control is human spleen tissue lysate.
PA5-20013 can be used with blocking peptide PEP-0132.
靶标信息
Tumor necrosis factor receptor superfamily member 13C (TNFRSF13C), also known as BAFFR, is a protein in humans is encoded by the TNFRSF13C gene. The BAFFR gene is mapped to chromosome 22q13. 1-q13. 31. It has got 184 amino acid transmembrane protein which is 56% identical to the mouse protein. B cell-activating factor (BAFF) enhances B-cell survival in vitro and is a regulator of the peripheral B-cell population. BAFF plays a crucial role in B cell development and can function through receptors other than BCMA.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: B cell-activating factor receptor; B-cell maturation defect; B-cell maturation defect 1; B-cell-activating factor receptor; BAFF receptor; BAFF-R; BLyS receptor 3; CD268; Tumor necrosis factor receptor superfamily member 13C; tumor necrosis factor receptor superfamily, member 13C
基因别名: 2010006P15Rik; BAFF-R; BAFFR; Bcmd; Bcmd-1; Bcmd1; BR3; BROMIX; CD268; CVID4; Lvis22; prolixin; RGD1560810; TNFRSF13C
UniProt ID: (Human) Q96RJ3, (Mouse) Q9D8D0
Entrez Gene ID: (Human) 115650, (Rat) 500910, (Mouse) 72049
B cell homeostasis
adaptive immune response
positive regulation of germinal center formation
positive regulation of B cell proliferation
T cell costimulation
B cell costimulation
tumor necrosis factor-mediated signaling pathway
positive regulation of T cell proliferation
positive regulation of interferon-gamma biosynthetic process
regulation of immune response
immune system process
