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Invitrogen
CD298 Recombinant Rabbit Monoclonal Antibody (23GB4740)
高级验证
This Antibody was verified by Knockdown to ensure that the antibody binds to the antigen stated.
图: 1 / 2
CD298 Antibody (MA5-53802) in WB
Western Blot analysis of CD298. Total cell lysates (30 μg) from various cell lines were loaded and separated by SDS-PAGE. The blot was incubated with CD298 recombinant monoclonal antibody (Product # MA5-53802) with a dilution of 1:5,000, followed by HRP-conjugated goat anti-rabbit secondary antibody with a dilution of 1:20,000. Image was developed using FeQTM ECL Substrate Kit.
产品信息
MA5-53802
产品规格
种属反应
Human,
Mouse,
Rat
宿主/亚型
Rabbit
/ IgG
Expression System
HEK293F
分类
Recombinant Monoclonal
类型
Antibody
克隆号
23GB4740
抗原
A synthesized peptide derived from human ATP1B3 (241-279AA).
偶联物
形式
Liquid
纯化类型
Affinity chromatography
保存液
PBS, pH 7.4, with 50% glycerol
内含物
0.02% sodium azide
保存条件
-20°C
运输条件
Wet ice (domestic); Dry ice (international)
靶标信息
The protein encoded by this gene belongs to the family of Na+/K+ and H+/K+ ATPases beta chain proteins, and to the subfamily of Na+/K+ -ATPases. Na+/K+ -ATPase is an integral membrane protein responsible for establishing and maintaining the electrochemical gradients of Na and K ions across the plasma membrane. These gradients are essential for osmoregulation, for sodium-coupled transport of a variety of organic and inorganic molecules, and for electrical excitability of nerve and muscle. This enzyme is composed of two subunits, a large catalytic subunit (alpha) and a smaller glycoprotein subunit (beta). The beta subunit regulates, through assembly of alpha/beta heterodimers, the number of sodium pumps transported to the plasma membrane. The glycoprotein subunit of Na+/K+ -ATPase is encoded by multiple genes. This gene encodes a beta 3 subunit. This gene encodes a beta 3 subunit. A pseudogene exists for this gene, and it is located on chromosome 2.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: ATPase, Na+/K+ beta 3 polypeptide; ATPase, Na+K+ transporting, beta polypeptide 3; ATPB-3; CD298; CD298 antigen; Na K-ATPase beta-3 subunit; Na+/K+ -ATPase beta 3 subunit; Sodium Potassium ATPase; Sodium/potassium-dependent ATPase subunit beta-3; Sodium/potassium-transporting ATPase subunit beta-3
基因别名: AA409958; AI664000; ATP1B3; ATPB-3; AW212096; CD298; NKAB3S
UniProt ID: (Human) P54709, (Mouse) P97370, (Rat) Q63377
Entrez Gene ID: (Human) 483, (Mouse) 11933, (Rat) 25390
transport
ion transport
potassium ion transport
sodium ion transport
cellular sodium ion homeostasis
potassium ion import
metal ion transport
cellular potassium ion homeostasis
positive regulation of ATPase activity
sodium ion export from cell
protein stabilization
protein localization to plasma membrane
membrane repolarization
positive regulation of potassium ion transmembrane transporter activity
positive regulation of sodium ion export from cell
positive regulation of potassium ion import
