Product References
Platelet factors attenuate inflammation and rescue cognition in ageing.
Nature
Schroer AB,Ventura PB,Sucharov J,Misra R,Chui MKK,Bieri G,Horowitz AM,Smith LK,Encabo K,Tenggara I,Couthouis J,Gross JD,Chan JM,Luke A,Villeda SA
Published figure using CD45R (B220) monoclonal antibody (Product # 13-0452-82) in Flow Cytometry
Tue Aug 01 00:00:00 EDT 2023
Immunostimulatory effects of a subcritical water extract of Ganoderma.
Biomedical reports
Hattori K,Takagi H,Ogata Y,Yamada T,Horiba H,Fukata K,Sakaida T,Yashiro Y,Hasegawa S,Tanaka H
13-0452-82 was used in Flow Cytometry, Immunohistochemistry (Frozen), Immunohistochemistry (Paraffin) to demonstrate that Ganoderma (SWEG) increased hematopoietic precursor cells, immature B cells, and NK cells in the bone marrow, and T cells in the thymus.
Sun Jan 01 00:00:00 EST 2023
Long-term culture-expanded alveolar macrophages restore their full epigenetic identity after transfer in vivo.
Nature immunology
Subramanian S,Busch CJ,Molawi K,Geirsdottir L,Maurizio J,Vargas Aguilar S,Belahbib H,Gimenez G,Yuda RAA,Burkon M,Favret J,Gholamhosseinian Najjar S,de Laval B,Kandalla PK,Sarrazin S,Alexopoulou L,Sieweke MH
13-0452-82 was used in Flow Cytometry to study long-term mouse ex vivo alveolar macrophage gene expression and culture adaptations.
Tue Mar 01 00:00:00 EST 2022
Transient expansion and myofibroblast conversion of adipogenic lineage precursors mediate bone marrow repair after radiation.
JCI insight
Zhong L,Yao L,Holdreith N,Yu W,Gui T,Miao Z,Elkaim Y,Li M,Gong Y,Pacifici M,Maity A,Busch TM,Joeng KS,Cengel K,Seale P,Tong W,Qin L
Published figure using CD45R (B220) monoclonal antibody (Product # 13-0452-82) in Flow Cytometry
Fri Apr 08 00:00:00 EDT 2022
Lenvatinib for effectively treating antiangiogenic drug-resistant nasopharyngeal carcinoma.
Cell death & disease
Sun Q,Wang Y,Ji H,Sun X,Xie S,Chen L,Li S,Zeng W,Chen R,Tang Q,Zuo J,Hou L,Hosaka K,Lu Y,Liu Y,Ye Y,Yang Y
Published figure using CD45R (B220) monoclonal antibody (Product # 13-0452-82) in Flow Cytometry
Fri Aug 19 00:00:00 EDT 2022
Tet-mediated DNA demethylation regulates specification of hematopoietic stem and progenitor cells during mammalian embryogenesis.
Science advances
Ma L,Tang Q,Gao X,Lee J,Lei R,Suzuki M,Zheng D,Ito K,Frenette PS,Dawlaty MM
Published figure using CD45R (B220) monoclonal antibody (Product # 13-0452-82) in Flow Cytometry
Fri Mar 04 00:00:00 EST 2022
Sphk2 deletion is involved in structural abnormalities and Th17 response but does not aggravate colon inflammation induced by sub-chronic stress.
Scientific reports
Martín-Hernández D,Gutiérrez IL,González-Prieto M,MacDowell KS,Robledo-Montaña J,Tendilla-Beltrán H,Calleja-Rodríguez N,Bris ÁG,Ulecia-Morón C,Moreno B,Caso JR,García-Bueno B,Rodrigues-Mascarenhas S,Marín-Jiménez I,Leza JC,Menchén L
Published figure using CD45R (B220) monoclonal antibody (Product # 13-0452-82) in Flow Cytometry
Tue Mar 08 00:00:00 EST 2022
MDMX acts as a pervasive preleukemic-to-acute myeloid leukemia transition mechanism.
Cancer cell
Ueda K,Kumari R,Schwenger E,Wheat JC,Bohorquez O,Narayanagari SR,Taylor SJ,Carvajal LA,Pradhan K,Bartholdy B,Todorova TI,Goto H,Sun D,Chen J,Shan J,Song Y,Montagna C,Xiong S,Lozano G,Pellagatti A,Boultwood J,Verma A,Steidl U
13-0452-82 was used in Flow cytometry/Cell sorting to identify MDMX overexpression as a pervasive preleukemic-to-AML transition mechanism in different genetically driven disease subtypes, and reveal Wnt/β-Catenin as a non-canonical MDMX-driven pathway with therapeutic potential for progression prevention and cancer interception.
Mon Apr 12 00:00:00 EDT 2021
Bone marrow adipogenic lineage precursors promote osteoclastogenesis in bone remodeling and pathologic bone loss.
The Journal of clinical investigation
Yu W,Zhong L,Yao L,Wei Y,Gui T,Li Z,Kim H,Holdreith N,Jiang X,Tong W,Dyment N,Liu XS,Yang S,Choi Y,Ahn J,Qin L
13-0452 was used in Flow cytometry/Cell sorting to identify MALPs as a critical player in controlling bone remodeling during normal bone metabolism and pathological bone loss in a RANKL-dependent fashion.
Tue Jan 19 00:00:00 EST 2021
Aged hematopoietic stem cells are refractory to bloodborne systemic rejuvenation interventions.
The Journal of experimental medicine
Ho TT,Dellorusso PV,Verovskaya EV,Bakker ST,Flach J,Smith LK,Ventura PB,Lansinger OM,Hérault A,Zhang SY,Kang YA,Mitchell CA,Villeda SA,Passegué E
Published figure using CD45R (B220) monoclonal antibody (Product # 13-0452-82) in Flow Cytometry
Mon Jul 05 00:00:00 EDT 2021
Monocyte-derived dendritic cells link localized secretory IgA deficiency to adaptive immune activation in COPD.
Mucosal immunology
Richmond BW,Mansouri S,Serezani A,Novitskiy S,Blackburn JB,Du RH,Fuseini H,Gutor S,Han W,Schaff J,Vasiukov G,Xin MK,Newcomb DC,Jin L,Blackwell TS,Polosukhin VV
Published figure using CD45R (B220) monoclonal antibody (Product # 13-0452-82) in Immunohistochemistry
Mon Mar 01 00:00:00 EST 2021
A rapid CRISPR competitive assay for in vitro and in vivo discovery of potential drug targets affecting the hematopoietic system.
Computational and structural biotechnology journal
Shen Y,Jiang L,Iyer VS,Raposo B,Dubnovitsky A,Boddul SV,Kasza Z,Wermeling F
Published figure using CD45R (B220) monoclonal antibody (Product # 13-0452-82) in Flow Cytometry
Wed Nov 10 00:00:00 EST 2021
Murine myeloid cell MCPIP1 suppresses autoimmunity by regulating B-cell expansion and differentiation.
Disease models & mechanisms
Dobosz E,Lorenz G,Ribeiro A,Würf V,Wadowska M,Kotlinowski J,Schmaderer C,Potempa J,Fu M,Koziel J,Lech M
Published figure using CD45R (B220) monoclonal antibody (Product # 13-0452-82) in Immunohistochemistry
Thu Mar 18 00:00:00 EDT 2021
Defining the Mechanistic Correlates of Protection Conferred by Whole-Cell Vaccination against Pseudomonas aeruginosa Acute Murine Pneumonia.
Infection and immunity
Sen-Kilic E,Blackwood CB,Huckaby AB,Horspool AM,Weaver KL,Malkowski AC,Witt WT,Bevere JR,Damron FH,Barbier M
Published figure using CD45R (B220) monoclonal antibody (Product # 13-0452-82) in Flow Cytometry
Tue Jan 19 00:00:00 EST 2021
Effects of signaling pathway inhibitors on hematopoietic stem cells.
Molecular medicine reports
Jiang Y,Xu Z,Ma N,Yin L,Hao C,Li J
13-0452 was used in Flow cytometry/Cell sorting to determine the effect of HDACs, mTOR, GSK‚3β and p38MAPK inhibitor combinations on the efficient expansion of HSCs using flow cytometry.
Fri Jan 01 00:00:00 EST 2021
Polyvinyl alcohol hydrolysis rate and molecular weight influence human and murine HSC activity ex vivo.
Stem cell research
Sudo K,Yamazaki S,Wilkinson AC,Nakauchi H,Nakamura Y
Published figure using CD45R (B220) monoclonal antibody (Product # 13-0452-82) in Flow Cytometry
Fri Oct 01 00:00:00 EDT 2021
Role of CXCL5 in Regulating Chemotaxis of Innate and Adaptive Leukocytes in Infected Lungs Upon Pulmonary Influenza Infection.
Frontiers in immunology
Guo L,Li N,Yang Z,Li H,Zheng H,Yang J,Chen Y,Zhao X,Mei J,Shi H,Worthen GS,Liu L
Published figure using CD45R (B220) monoclonal antibody (Product # 13-0452-82) in Immunohistochemistry
Tue Feb 08 00:00:00 EST 2022
Hypoxia-induced miR-210 modulates the inflammatory response and fibrosis upon acute ischemia.
Cell death & disease
Zaccagnini G,Greco S,Longo M,Maimone B,Voellenkle C,Fuschi P,Carrara M,Creo P,Maselli D,Tirone M,Mazzone M,Gaetano C,Spinetti G,Martelli F
Published figure using CD45R (B220) monoclonal antibody (Product # 13-0452-82) in Immunohistochemistry
Sat May 01 00:00:00 EDT 2021
Ibrutinib does not prevent kidney fibrosis following acute and chronic injury.
Scientific reports
Belliere J,Casemayou A,Colliou E,El Hachem H,Kounde C,Piedrafita A,Feuillet G,Schanstra JP,Faguer S
Published figure using CD45R (B220) monoclonal antibody (Product # 13-0452-82) in Immunohistochemistry
Mon Jun 07 00:00:00 EDT 2021
High-throughput analysis of lung immune cells in a combined murine model of agriculture dust-triggered airway inflammation with rheumatoid arthritis.
PloS one
Gaurav R,Mikuls TR,Thiele GM,Nelson AJ,Niu M,Guda C,Eudy JD,Barry AE,Wyatt TA,Romberger DJ,Duryee MJ,England BR,Poole JA
Published figure using CD45R (B220) monoclonal antibody (Product # 13-0452-82) in Immunohistochemistry
Thu Jul 08 00:00:00 EDT 2021
Proteostasis in dendritic cells is controlled by the PERK signaling axis independently of ATF4.
Life science alliance
Mendes A,Gigan JP,Rodriguez Rodrigues C,Choteau SA,Sanseau D,Barros D,Almeida C,Camosseto V,Chasson L,Paton AW,Paton JC,Argüello RJ,Lennon-Duménil AM,Gatti E,Pierre P
Published figure using CD45R (B220) monoclonal antibody (Product # 13-0452-82) in Immunohistochemistry
Mon Feb 01 00:00:00 EST 2021
Impaired HA-specific T follicular helper cell and antibody responses to influenza vaccination are linked to inflammation in humans.
eLife
Hill DL,Whyte CE,Innocentin S,Lee JL,Dooley J,Wang J,James EA,Lee JC,Kwok WW,Zand MS,Liston A,Carr EJ,Linterman MA
Published figure using CD45R (B220) monoclonal antibody (Product # 13-0452-82) in Flow Cytometry
Tue Nov 02 00:00:00 EDT 2021
Metabolic preconditioning in CD4+ T cells restores inducible immune tolerance in lupus-prone mice.
JCI insight
Wilson CS,Stocks BT,Hoopes EM,Rhoads JP,McNew KL,Major AS,Moore DJ
Published figure using CD45R (B220) monoclonal antibody (Product # 13-0452-82) in Flow Cytometry
Fri Oct 08 00:00:00 EDT 2021
The folate cycle enzyme MTHFD2 induces cancer immune evasion through PD-L1 up-regulation.
Nature communications
Shang M,Yang H,Yang R,Chen T,Fu Y,Li Y,Fang X,Zhang K,Zhang J,Li H,Cao X,Gu J,Xiao J,Zhang Q,Liu X,Yu Q,Wang T
Published figure using CD45R (B220) monoclonal antibody (Product # 13-0452-82) in Flow Cytometry
Mon Mar 29 00:00:00 EDT 2021
Type 2 diabetic mice enter a state of spontaneous hibernation-like suspended animation following accumulation of uric acid.
The Journal of biological chemistry
Zhao Y,Cheng R,Zhao Y,Ge W,Yang Y,Ding Z,Xu X,Wang Z,Wu Z,Zhang J
Published figure using CD45R (B220) monoclonal antibody (Product # 13-0452-82) in Flow Cytometry
Fri Oct 01 00:00:00 EDT 2021
Targeting Ovarian Carcinoma with TSP-1:CD47 Antagonist TAX2 Activates Anti-Tumor Immunity.
Cancers
Jeanne A,Sarazin T,Charlé M,Moali C,Fichel C,Boulagnon-Rombi C,Callewaert M,Andry MC,Diesis E,Delolme F,Rioult D,Dedieu S
Published figure using CD45R (B220) monoclonal antibody (Product # 13-0452-82) in Immunohistochemistry
Thu Oct 07 00:00:00 EDT 2021
Histone deacetylase 3 represses cholesterol efflux during CD4+ T-cell activation.
eLife
Wilfahrt D,Philips RL,Lama J,Kizerwetter M,Shapiro MJ,McCue SA,Kennedy MM,Rajcula MJ,Zeng H,Shapiro VS
Published figure using CD45R (B220) monoclonal antibody (Product # 13-0452-82) in Protein Assays and Analysis
Thu Dec 02 00:00:00 EST 2021
Mechanism of a COVID-19 nanoparticle vaccine candidate that elicits a broadly neutralizing antibody response to SARS-CoV-2 variants.
Science advances
Zhang YN,Paynter J,Sou C,Fourfouris T,Wang Y,Abraham C,Ngo T,Zhang Y,He L,Zhu J
Published figure using CD45R (B220) monoclonal antibody (Product # 13-0452-82) in Immunohistochemistry (Frozen)
Fri Oct 22 00:00:00 EDT 2021
TNF-α-induced alterations in stromal progenitors enhance leukemic stem cell growth via CXCR2 signaling.
Cell reports
Agarwal P,Li H,Choi K,Hueneman K,He J,Welner RS,Starczynowski DT,Bhatia R
13-0452-82 was used in Flow Cytometry to find that TNF-α-mediated alterations in CML BM stromal niches enhance support of LSC maintenance and growth via CXCL1-CXCR2 signaling and that CXCR2 inhibition effectively depletes CML LSCs.
Tue Jul 13 00:00:00 EDT 2021
SARS-CoV-2 mRNA Vaccines Foster Potent Antigen-Specific Germinal Center Responses Associated with Neutralizing Antibody Generation.
Immunity
Lederer K,Castaño D,Gómez Atria D,Oguin TH,Wang S,Manzoni TB,Muramatsu H,Hogan MJ,Amanat F,Cherubin P,Lundgreen KA,Tam YK,Fan SHY,Eisenlohr LC,Maillard I,Weissman D,Bates P,Krammer F,Sempowski GD,Pardi N,Locci M
Published figure using CD45R (B220) monoclonal antibody (Product # 13-0452-82) in Flow Cytometry
Tue Dec 15 00:00:00 EST 2020
Cathepsin S Regulates Antigen Processing and T Cell Activity in Non-Hodgkin Lymphoma.
Cancer cell
Dheilly E,Battistello E,Katanayeva N,Sungalee S,Michaux J,Duns G,Wehrle S,Sordet-Dessimoz J,Mina M,Racle J,Farinha P,Coukos G,Gfeller D,Mottok A,Kridel R,Correia BE,Steidl C,Bassani-Sternberg M,Ciriello G,Zoete V,Oricchio E
13-0452 was used in Immunohistochemistry to find that follicular lymphoma patients harbor a recurrent hotspot mutation targeting tyrosine 132 (Y132D) in cathepsin S (CTSS) that enhances protein activity.
Mon May 11 00:00:00 EDT 2020
RNA Demethylase ALKBH5 Selectively Promotes Tumorigenesis and Cancer Stem Cell Self-Renewal in Acute Myeloid Leukemia.
Cell stem cell
Shen C,Sheng Y,Zhu AC,Robinson S,Jiang X,Dong L,Chen H,Su R,Yin Z,Li W,Deng X,Chen Y,Hu YC,Weng H,Huang H,Prince E,Cogle CR,Sun M,Zhang B,Chen CW,Marcucci G,He C,Qian Z,Chen J
13-0452-82 was used in Flow Cytometry to reveal crucial functions of ALKBH5 in leukemogenesis and LSC/LIC self-renewal/maintenance and highlight the therapeutic potential of targeting the ALKBH5/m6A axis.
Thu Jul 02 00:00:00 EDT 2020
BCG vaccination-induced emergency granulopoiesis provides rapid protection from neonatal sepsis.
Science translational medicine
Brook B,Harbeson DJ,Shannon CP,Cai B,He D,Ben-Othman R,Francis F,Huang J,Varankovich N,Liu A,Bao W,Bjerregaard-Andersen M,Schaltz-Buchholzer F,Sanca L,Golding CN,Larsen KL,Levy O,Kampmann B,Tan R,Charles A,Wynn JL,Shann F,Aaby P,Benn CS,Tebbutt SJ,Kollmann TR,Amenyogbe N
13-0452 was used in Flow cytometry/Cell sorting to show that BCG was also protective in a mouse model of neonatal polymicrobial sepsis, where it induced granulocyte colony-stimulating factor (G-CSF) within hours of administration.
Wed May 06 00:00:00 EDT 2020
Deregulated Notch and Wnt signaling activates early-stage myeloid regeneration pathways in leukemia.
The Journal of experimental medicine
Kang YA,Pietras EM,Passegué E
Published figure using CD45R (B220) monoclonal antibody (Product # 13-0452-82) in Flow Cytometry
Mon Mar 02 00:00:00 EST 2020
Long-term ex vivo expansion of mouse hematopoietic stem cells.
Nature protocols
Wilkinson AC,Ishida R,Nakauchi H,Yamazaki S
13-0452 was used in Flow cytometry/Cell sorting to describe a simple platform for the expansion of functional mouse hematopoietic stem cells ex vivo for >1 month under fully defined albumin-free conditions.
Sat Feb 01 00:00:00 EST 2020
Single cell and tissue-transcriptomic analysis of murine bladders reveals age- and TNFα-dependent but microbiota-independent tertiary lymphoid tissue formation.
Mucosal immunology
Ligon MM,Wang C,DeJong EN,Schulz C,Bowdish DME,Mysorekar IU
13-0452 was used in Immunohistochemistry-immunofluorescence to indicate that chronic, age-associated inflammation underlies a fundamental alteration to the bladder and establishes a resource for further investigation of the bladder immune system in homeostasis, aging, and disease.
Sun Nov 01 00:00:00 EDT 2020
Th2 cells promote eosinophil-independent pathology in a murine model of allergic bronchopulmonary aspergillosis.
European journal of immunology
Dietschmann A,Schruefer S,Krappmann S,Voehringer D
13-0452-82 was used in Flow Cytometry to use a mouse model of ABPA to investigate the role of eosinophils and T cell-derived IL-4/IL-13 for induction of allergic lung inflammation.
Wed Jul 01 00:00:00 EDT 2020
Synergistic factors control kinase-phosphatase organization in B-cells engaged with supported bilayers.
Molecular biology of the cell
Núñez MF,Wisser K,Veatch SL
Published figure using CD45R (B220) monoclonal antibody (Product # 13-0452-82) in Immunocytochemistry
Thu Mar 19 00:00:00 EDT 2020
Pituitary Adenylate Cyclase-Activating Polypeptide Alleviates Intestinal, Extra-Intestinal and Systemic Inflammatory Responses during Acute Campylobacter jejuni-induced Enterocolitis in Mice.
Pathogens (Basel, Switzerland)
Heimesaat MM,Mousavi S,Kløve S,Genger C,Weschka D,Tamas A,Reglodi D,Bereswill S
Published figure using CD45R (B220) monoclonal antibody (Product # 13-0452-82) in Immunohistochemistry (Paraffin)
Wed Sep 30 00:00:00 EDT 2020
Pituitary Adenylate Cyclase-Activating Polypeptide Alleviates Intestinal, Extra-Intestinal and Systemic Inflammatory Responses during Acute Campylobacter jejuni-induced Enterocolitis in Mice.
Pathogens (Basel, Switzerland)
Heimesaat MM,Mousavi S,Kløve S,Genger C,Weschka D,Tamas A,Reglodi D,Bereswill S
Published figure using CD45R (B220) monoclonal antibody (Product # 13-0452-82) in Immunohistochemistry (Paraffin)
Wed Sep 30 00:00:00 EDT 2020
The lysophospholipase D enzyme Gdpd3 is required to maintain chronic myelogenous leukaemia stem cells.
Nature communications
Naka K,Ochiai R,Matsubara E,Kondo C,Yang KM,Hoshii T,Araki M,Araki K,Sotomaru Y,Sasaki K,Mitani K,Kim DW,Ooshima A,Kim SJ
13-0452 was used in Flow cytometry/Cell sorting to show that disruption of the Gdpd3 gene encoding a lysophospholipase D enzyme decreases the self-renewal capacity of murine chronic myelogenous leukaemia stem cells.
Thu Sep 17 00:00:00 EDT 2020
The lysophospholipase D enzyme Gdpd3 is required to maintain chronic myelogenous leukaemia stem cells.
Nature communications
Naka K,Ochiai R,Matsubara E,Kondo C,Yang KM,Hoshii T,Araki M,Araki K,Sotomaru Y,Sasaki K,Mitani K,Kim DW,Ooshima A,Kim SJ
13-0452 was used in Flow cytometry/Cell sorting to show that disruption of the Gdpd3 gene encoding a lysophospholipase D enzyme decreases the self-renewal capacity of murine chronic myelogenous leukaemia stem cells.
Thu Sep 17 00:00:00 EDT 2020
Toll-Like Receptor-4 Dependent Intestinal and Systemic Sequelae Following Peroral Campylobacter coli Infection of IL10 Deficient Mice Harboring a Human Gut Microbiota.
Pathogens (Basel, Switzerland)
Kløve S,Genger C,Mousavi S,Weschka D,Bereswill S,Heimesaat MM
Published figure using CD45R (B220) monoclonal antibody (Product # 13-0452-82) in Immunohistochemistry
Mon May 18 00:00:00 EDT 2020
Ischemia Reperfusion Injury Triggers CXCL13 Release and B-Cell Recruitment After Allogenic Kidney Transplantation.
Frontiers in immunology
Kreimann K,Jang MS,Rong S,Greite R,von Vietinghoff S,Schmitt R,Bräsen JH,Schiffer L,Gerstenberg J,Vijayan V,Dittrich-Breiholz O,Wang L,Karsten CM,Gwinner W,Haller H,Immenschuh S,Gueler F
Published figure using CD45R (B220) monoclonal antibody (Product # 13-0452-82) in Immunohistochemistry
Mon Apr 12 00:00:00 EDT 2021
Overcoming Immunological Challenges to Helper-Dependent Adenoviral Vector-Mediated Long-Term CFTR Expression in Mouse Airways.
Genes
Cao H,Duan R,Hu J
Published figure using CD45R (B220) monoclonal antibody (Product # 13-0452-82) in Immunohistochemistry
Mon May 18 00:00:00 EDT 2020
Myeloid Cell CK2 Regulates Inflammation and Resistance to Bacterial Infection.
Frontiers in immunology
Larson SR,Bortell N,Illies A,Crisler WJ,Matsuda JL,Lenz LL
Published figure using CD45R (B220) monoclonal antibody (Product # 13-0452-82) in Flow Cytometry
Tue Jul 27 00:00:00 EDT 2021
Shp1 Loss Enhances Macrophage Effector Function and Promotes Anti-Tumor Immunity.
Frontiers in immunology
Myers DR,Abram CL,Wildes D,Belwafa A,Welsh AMN,Schulze CJ,Choy TJ,Nguyen T,Omaque N,Hu Y,Singh M,Hansen R,Goldsmith MA,Quintana E,Smith JAM,Lowell CA
Published figure using CD45R (B220) monoclonal antibody (Product # 13-0452-82) in Flow Cytometry
Mon Jun 14 00:00:00 EDT 2021
Fucoxanthin Ameliorates Atopic Dermatitis Symptoms by Regulating Keratinocytes and Regulatory Innate Lymphoid Cells.
International journal of molecular sciences
Natsume C,Aoki N,Aoyama T,Senda K,Matsui M,Ikegami A,Tanaka K,Azuma YT,Fujita T
Published figure using CD45R (B220) monoclonal antibody (Product # 13-0452-82) in Immunohistochemistry
Sun Mar 22 00:00:00 EDT 2020
The Host-Specific Intestinal Microbiota Composition Impacts Campylobacter coli Infection in a Clinical Mouse Model of Campylobacteriosis.
Pathogens (Basel, Switzerland)
Heimesaat MM,Genger C,Klove S,Weschka D,Mousavi S,Bereswill S
Published figure using CD45R (B220) monoclonal antibody (Product # 13-0452-82) in Immunohistochemistry
Tue Sep 29 00:00:00 EDT 2020
Lysosomal Acid Lipase Is Required for Donor T Cells to Induce Graft-versus-Host Disease.
Cell reports
Nguyen HD,Ticer T,Bastian D,Kuril S,Li H,Du H,Yan C,Yu XZ
13-0452 was used in Flow cytometry/Cell sorting to reveal the role of LAL in T cell alloresponse and pathogenicity and validates LAL as a target for controlling GVHD and tumor relapse after allo-HCT.
Tue Oct 27 00:00:00 EDT 2020
Critical role of WNK1 in MYC-dependent early mouse thymocyte development.
eLife
Köchl R,Vanes L,Llorian Sopena M,Chakravarty P,Hartweger H,Fountain K,White A,Cowan J,Anderson G,Tybulewicz VL
13-0452 was used in Flow cytometry/Cell sorting to ind that WNK1 is required for the transition of double negative (DN) thymocytes through the β-selection checkpoint and subsequent proliferation and differentiation into double positive (DP) thymocytes.
Wed Oct 14 00:00:00 EDT 2020
Cep55 overexpression promotes genomic instability and tumorigenesis in mice.
Communications biology
Sinha D,Nag P,Nanayakkara D,Duijf PHG,Burgess A,Raninga P,Smits VAJ,Bain AL,Subramanian G,Wall M,Finnie JW,Kalimutho M,Khanna KK
Published figure using CD45R (B220) monoclonal antibody (Product # 13-0452-82) in Immunohistochemistry
Wed Oct 21 00:00:00 EDT 2020
Analysis of Myeloid Cells in Mouse Tissues with Flow Cytometry.
STAR protocols
Liu Z,Gu Y,Shin A,Zhang S,Ginhoux F
Published figure using CD45R (B220) monoclonal antibody (Product # 13-0452-82) in Flow Cytometry
Fri Jun 19 00:00:00 EDT 2020
Aging-Affected MSC Functions and Severity of Periodontal Tissue Destruction in a Ligature-Induced Mouse Periodontitis Model.
International journal of molecular sciences
Aung KT,Akiyama K,Kunitomo M,Mun AY,Tosa I,Nguyen HTT,Zhang J,Kohno T,Ono M,Hara ES,Kuboki T
Published figure using CD45R (B220) monoclonal antibody (Product # 13-0452-82) in Immunocytochemistry
Fri Oct 30 00:00:00 EDT 2020
Requirements for the differentiation of innate T-bethigh memory-phenotype CD4+ T lymphocytes under steady state.
Nature communications
Kawabe T,Yi J,Kawajiri A,Hilligan K,Fang D,Ishii N,Yamane H,Zhu J,Jankovic D,Kim KS,Trinchieri G,Sher A
Published figure using CD45R (B220) monoclonal antibody (Product # 13-0452-82) in Immunohistochemistry
Mon Jul 06 00:00:00 EDT 2020
Methylation of a CGATA element inhibits binding and regulation by GATA-1.
Nature communications
Yang L,Chen Z,Stout ES,Delerue F,Ittner LM,Wilkins MR,Quinlan KGR,Crossley M
13-0452 was used in Flow cytometry/Cell sorting to show that the erythroid transcription factor GATA-1 - that typically binds T/AGATA sites - can also recognise CGATA elements, but only if the CpG dinucleotide is unmethylated.
Fri May 22 00:00:00 EDT 2020
Micro-environmental sensing by bone marrow stroma identifies IL-6 and TGFβ1 as regulators of hematopoietic ageing.
Nature communications
Valletta S,Thomas A,Meng Y,Ren X,Drissen R,Sengül H,Di Genua C,Nerlov C
13-0452-82 was used in Flow Cytometry to investigate if hematopoietic stem cells-intrinsic and -extrinsic mechanisms are involved in age-associated hematopoietic decline, and identify therapeutic targets that promote their reversal.
Fri Aug 14 00:00:00 EDT 2020
Single cell transcriptomics identifies a unique adipose lineage cell population that regulates bone marrow environment.
eLife
Zhong L,Yao L,Tower RJ,Wei Y,Miao Z,Park J,Shrestha R,Wang L,Yu W,Holdreith N,Huang X,Zhang Y,Tong W,Gong Y,Ahn J,Susztak K,Dyment N,Li M,Long F,Chen C,Seale P,Qin L
13-0452 was used in Flow cytometry/Cell sorting to computationally define mesenchymal progenitors at different stages and delineate their bi-lineage differentiation paths in young, adult and aging mice.
Tue Apr 14 00:00:00 EDT 2020
Osterix-Cre marks distinct subsets of CD45- and CD45+ stromal populations in extra-skeletal tumors with pro-tumorigenic characteristics.
eLife
Ricci B,Tycksen E,Celik H,Belle JI,Fontana F,Civitelli R,Faccio R
13-0452 was used in Flow cytometry/Cell sorting to find Osx transcript and Osx protein expression early during hematopoiesis, in subsets of hematopoietic stem cells and multipotent progenitor populations.
Wed Aug 05 00:00:00 EDT 2020
CD71+ Erythroid Cells in Human Neonates Exhibit Immunosuppressive Properties and Compromise Immune Response Against Systemic Infection in Neonatal Mice.
Frontiers in immunology
Elahi S,Vega-López MA,Herman-Miguel V,Ramírez-Estudillo C,Mancilla-Ramírez J,Motyka B,West L,Oyegbami O
13-0452-82 was used in Flow Cytometry to study the frequency and functionality of CD71+ erythroid cells in the peripheral blood of human newborns/children from 1-day to 5-year and compared them with their counterparts in the neonatal mice.
Mon Dec 28 00:00:00 EST 2020
Anti-commensal IgG Drives Intestinal Inflammation and Type 17 Immunity in Ulcerative Colitis.
Immunity
Castro-Dopico T,Dennison TW,Ferdinand JR,Mathews RJ,Fleming A,Clift D,Stewart BJ,Jing C,Strongili K,Labzin LI,Monk EJM,Saeb-Parsy K,Bryant CE,Clare S,Parkes M,Clatworthy MR
Published figure using CD45R (B220) monoclonal antibody (Product # 13-0452-82) in Immunofluorescence
Tue Apr 16 00:00:00 EDT 2019
Anti-commensal IgG Drives Intestinal Inflammation and Type 17 Immunity in Ulcerative Colitis.
Immunity
Castro-Dopico T,Dennison TW,Ferdinand JR,Mathews RJ,Fleming A,Clift D,Stewart BJ,Jing C,Strongili K,Labzin LI,Monk EJM,Saeb-Parsy K,Bryant CE,Clare S,Parkes M,Clatworthy MR
Published figure using CD45R (B220) monoclonal antibody (Product # 13-0452-82) in Immunofluorescence
Tue Apr 16 00:00:00 EDT 2019
Metabolic Imaging Reveals a Unique Preference of Symmetric Cell Division and Homing of Leukemia-Initiating Cells in an Endosteal Niche.
Cell metabolism
Hao X,Gu H,Chen C,Huang D,Zhao Y,Xie L,Zou Y,Shu HS,Zhang Y,He X,Lai X,Zhang X,Zhou BO,Zhang CC,Chen GQ,Yu Z,Yang Y,Zheng J
13-0452 was used in Flow cytometry/Cell sorting to provide a unique angle for the study of metabolisms in stem cells, and may lead to development of novel strategies for cancer treatment.
Tue Apr 02 00:00:00 EDT 2019
Mesenchymal Niche-Specific Expression of Cxcl12 Controls Quiescence of Treatment-Resistant Leukemia Stem Cells.
Cell stem cell
Agarwal P,Isringhausen S,Li H,Paterson AJ,He J,Gomariz Á,Nagasawa T,Nombela-Arrieta C,Bhatia R
13-0452-82 was used in Flow Cytometry to highlight a critical role of niche-specific effects of Cxcl12 expression in maintaining quiescence of TKI-resistant LSC populations.
Thu May 02 00:00:00 EDT 2019
SIRT1 regulates metabolism and leukemogenic potential in CML stem cells.
The Journal of clinical investigation
Abraham A,Qiu S,Chacko BK,Li H,Paterson A,He J,Agarwal P,Shah M,Welner R,Darley-Usmar VM,Bhatia R
13-0452 was used in Flow cytometry/Cell sorting to demonstrate an important role for SIRT1 in leukemia development.
Mon Jun 10 00:00:00 EDT 2019
Tpl2 Protects Against Fulminant Hepatitis Through Mobilization of Myeloid-Derived Suppressor Cells.
Frontiers in immunology
Xu J,Pei S,Wang Y,Liu J,Qian Y,Huang M,Zhang Y,Xiao Y
Published figure using CD45R (B220) monoclonal antibody (Product # 13-0452-82) in Flow Cytometry
Wed Oct 14 00:00:00 EDT 2020
Bacteroides fragilis polysaccharide A induces IL-10 secreting B and T cells that prevent viral encephalitis.
Nature communications
Ramakrishna C,Kujawski M,Chu H,Li L,Mazmanian SK,Cantin EM
Published figure using CD45R (B220) monoclonal antibody (Product # 13-0452-82) in Flow Cytometry
Tue May 14 00:00:00 EDT 2019
The Hematopoietic Oxidase NOX2 Regulates Self-Renewal of Leukemic Stem Cells.
Cell reports
Adane B,Ye H,Khan N,Pei S,Minhajuddin M,Stevens BM,Jones CL,D'Alessandro A,Reisz JA,Zaberezhnyy V,Gasparetto M,Ho TC,Kelly KK,Myers JR,Ashton JM,Siegenthaler J,Kume T,Campbell EL,Pollyea DA,Becker MW,Jordan CT
Published figure using CD45R (B220) monoclonal antibody (Product # 13-0452-82) in Flow Cytometry
Tue Apr 02 00:00:00 EDT 2019
In Situ Modification of Tissue Stem and Progenitor Cell Genomes.
Cell reports
Goldstein JM,Tabebordbar M,Zhu K,Wang LD,Messemer KA,Peacker B,Ashrafi Kakhki S,Gonzalez-Celeiro M,Shwartz Y,Cheng JKW,Xiao R,Barungi T,Albright C,Hsu YC,Vandenberghe LH,Wagers AJ
13-0452 was used in Flow cytometry/Cell sorting to demonstrate in vivo transduction of endogenous tissue stem cells in the muscle, blood, and skin by systemic or local administration of adeno-associated viruses (AAVs) encoding genome-modifying enzymes.
Tue Apr 23 00:00:00 EDT 2019
N-Cadherin-Expressing Bone and Marrow Stromal Progenitor Cells Maintain Reserve Hematopoietic Stem Cells.
Cell reports
Zhao M,Tao F,Venkatraman A,Li Z,Smith SE,Unruh J,Chen S,Ward C,Qian P,Perry JM,Marshall H,Wang J,He XC,Li L
13-0452 was used in Flow cytometry/Cell sorting to report that N-cad+ cells were functional bone and marrow stromal progenitor cells, giving rise to osteoblasts, adipocytes, and chondrocytes both in vitro and in vivo.
Tue Jan 15 00:00:00 EST 2019
Thioredoxin-1 confines T cell alloresponse and pathogenicity in graft-versus-host disease.
The Journal of clinical investigation
Sofi MH,Wu Y,Schutt SD,Dai M,Daenthanasanmak A,Heinrichs Voss J,Nguyen H,Bastian D,Iamsawat S,Selvam SP,Liu C,Maulik N,Ogretmen B,Jin J,Mehrotra S,Yu XZ
13-0452-82 was used in Flow Cytometry to target the ROS pathway, which can be readily translated into clinic.
Thu May 02 00:00:00 EDT 2019
Adrenergic nerve degeneration in bone marrow drives aging of the hematopoietic stem cell niche.
Nature medicine
Maryanovich M,Zahalka AH,Pierce H,Pinho S,Nakahara F,Asada N,Wei Q,Wang X,Ciero P,Xu J,Leftin A,Frenette PS
Published figure using CD45R (B220) monoclonal antibody (Product # 13-0452-82) in Flow Cytometry
Fri Jun 01 00:00:00 EDT 2018
Bone marrow niche trafficking of miR-126 controls the self-renewal of leukemia stem cells in chronic myelogenous leukemia.
Nature medicine
Zhang B,Nguyen LXT,Li L,Zhao D,Kumar B,Wu H,Lin A,Pellicano F,Hopcroft L,Su YL,Copland M,Holyoake TL,Kuo CJ,Bhatia R,Snyder DS,Ali H,Stein AS,Brewer C,Wang H,McDonald T,Swiderski P,Troadec E,Chen CC,Dorrance A,Pullarkat V,Yuan YC,Perrotti D,Carlesso N,Forman SJ,Kortylewski M,Kuo YH,Marcucci G
13-0452 was used in Flow cytometry/Cell sorting to demonstrate how bone marrow endothelial cells supply miR-126 to leukemia stem cells in chronic myelogenous leukemia which modulates their quiescence and self-renewal.
Tue May 01 00:00:00 EDT 2018
Mitophagy in Intestinal Epithelial Cells Triggers Adaptive Immunity during Tumorigenesis.
Cell
Ziegler PK,Bollrath J,Pallangyo CK,Matsutani T,Canli Ö,De Oliveira T,Diamanti MA,Müller N,Gamrekelashvili J,Putoczki T,Horst D,Mankan AK,Öner MG,Müller S,Müller-Höcker J,Kirchner T,Slotta-Huspenina J,Taketo MM,Reinheckel T,Dröse S,Larner AC,Wels WS,Ernst M,Greten TF,Arkan MC,Korn T,Wirth D,Greten FR
Published figure using CD45R (B220) monoclonal antibody (Product # 13-0452-82) in Flow Cytometry
Thu Jun 28 00:00:00 EDT 2018
Oxysterol Sensing through the Receptor GPR183 Promotes the Lymphoid-Tissue-Inducing Function of Innate Lymphoid Cells and Colonic Inflammation.
Immunity
Emgård J,Kammoun H,García-Cassani B,Chesné J,Parigi SM,Jacob JM,Cheng HW,Evren E,Das S,Czarnewski P,Sleiers N,Melo-Gonzalez F,Kvedaraite E,Svensson M,Scandella E,Hepworth MR,Huber S,Ludewig B,Peduto L,Villablanca EJ,Veiga-Fernandes H,Pereira JP,Flavell RA,Willinger T
Published figure using CD45R (B220) monoclonal antibody (Product # 13-0452-82) in Immunofluorescence
Tue Jan 16 00:00:00 EST 2018
Amphiregulin-Producing Pathogenic Memory T Helper 2 Cells Instruct Eosinophils to Secrete Osteopontin and Facilitate Airway Fibrosis.
Immunity
Morimoto Y,Hirahara K,Kiuchi M,Wada T,Ichikawa T,Kanno T,Okano M,Kokubo K,Onodera A,Sakurai D,Okamoto Y,Nakayama T
13-0452-82 was used in Flow Cytometry to find that interleukin-33 (IL-33) enhanced amphiregulin production by the IL-33 receptor, ST2hi memory T helper 2 (Th2) cells.
Tue Jul 17 00:00:00 EDT 2018
Microbial symbionts regulate the primary Ig repertoire.
The Journal of experimental medicine
Chen Y,Chaudhary N,Yang N,Granato A,Turner JA,Howard SL,Devereaux C,Zuo T,Shrestha A,Goel RR,Neuberg D,Wesemann DR
Published figure using CD45R (B220) monoclonal antibody (Product # 13-0452-82) in Immunofluorescence
Mon May 07 00:00:00 EDT 2018
IL1RAP potentiates multiple oncogenic signaling pathways in AML.
The Journal of experimental medicine
Mitchell K,Barreyro L,Todorova TI,Taylor SJ,Antony-Debré I,Narayanagari SR,Carvajal LA,Leite J,Piperdi Z,Pendurti G,Mantzaris I,Paietta E,Verma A,Gritsman K,Steidl U
13-0452 was used in Flow cytometry/Cell sorting to show that targeting of interleukin-1 receptor accessory protein via RNA interference, genetic deletion, or antibodies inhibits acute myeloid leukaemia pathogenesis in vitro and in vivo.
Mon Jun 04 00:00:00 EDT 2018
Proapoptotic BIM Impacts B Lymphoid Homeostasis by Limiting the Survival of Mature B Cells in a Cell-Autonomous Manner.
Frontiers in immunology
Liu R,King A,Bouillet P,Tarlinton DM,Strasser A,Heierhorst J
Published figure using CD45R (B220) monoclonal antibody (Product # 13-0452-82) in Flow Cytometry
Wed May 01 00:00:00 EDT 2019
Protection by and maintenance of CD4 effector memory and effector T cell subsets in persistent malaria infection.
PLoS pathogens
Opata MM,Ibitokou SA,Carpio VH,Marshall KM,Dillon BE,Carl JC,Wilson KD,Arcari CM,Stephens R
13-0452 was used in Flow cytometry/Cell sorting to elucidate four mechanisms of Tem maintenance, and identify two long-lived T cell subsets (TemLate, TeffEarly) that may represent correlates of protection or a target for longerlived vaccine-induced protection against malaria blood-stages.
Sun Apr 01 00:00:00 EDT 2018
Host Tumor Suppressor p18INK4c Functions as a Potent Cell-Intrinsic Inhibitor of Murine Gammaherpesvirus 68 Reactivation and Pathogenesis.
Journal of virology
Niemeyer BF,Oko LM,Medina EM,Oldenburg DG,White DW,Cool CD,Clambey ET,van Dyk LF
Published figure using CD45R (B220) monoclonal antibody (Product # 13-0452-82) in Flow Cytometry
Thu Mar 15 00:00:00 EDT 2018
Inactivation of mTORC1 Signaling in Osterix-Expressing Cells Impairs B-cell Differentiation.
Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research
Wang Y,Xiao M,Tao C,Chen J,Wang Z,Yang J,Chen Z,Zou Z,Liu A,Cai D,Jiang Y,Ding C,Li M,Bai X
Published figure using CD45R (B220) monoclonal antibody (Product # 13-0452-82) in Flow Cytometry
Sun Apr 01 00:00:00 EDT 2018
Bruton's Tyrosine Kinase Is Not Essential for B Cell Survival beyond Early Developmental Stages.
Journal of immunology (Baltimore, Md. : 1950)
Nyhoff LE,Clark ES,Barron BL,Bonami RH,Khan WN,Kendall PL
13-0452 was used in Flow cytometry/Cell sorting to raise the possibility that Btk may also be expendable for survival of mature human B cells, therefore requiring prolonged dosing to be effective, and that success of BTK inhibitors may depend in part on off-target effects.
Sun Apr 01 00:00:00 EDT 2018
Loss of DEK induces radioresistance of murine restricted hematopoietic progenitors.
Experimental hematology
Serrano-Lopez J,Nattamai K,Pease NA,Shephard MS,Wellendorf AM,Sertorio M,Smith EA,Geiger H,Wells SI,Cancelas JA,Privette Vinnedge LM
13-0452 was used in Flow cytometry/Cell sorting to investigate the role of DEK in normal hematopoiesis and response to DNA damaging agents in vivo.
Thu Mar 01 00:00:00 EST 2018
Tanshinone IIA and Astragaloside IV promote the angiogenesis of mesenchymal stem cell-derived endothelial cell-like cells via upregulation of Cx37, Cx40 and Cx43.
Experimental and therapeutic medicine
Li Z,Zhang S,Cao L,Li W,Ye YC,Shi ZX,Wang ZR,Sun LX,Wang JW,Jia LT,Wang W
Published figure using CD45R (B220) monoclonal antibody (Product # 13-0452-82) in Flow Cytometry
Thu Feb 01 00:00:00 EST 2018
miR-143/145 differentially regulate hematopoietic stem and progenitor activity through suppression of canonical TGFβ signaling.
Nature communications
Lam J,van den Bosch M,Wegrzyn J,Parker J,Ibrahim R,Slowski K,Chang L,Martinez-Høyer S,Condorelli G,Boldin M,Deng Y,Umlandt P,Fuller M,Karsan A
Published figure using CD45R (B220) monoclonal antibody (Product # 13-0452-82) in Flow Cytometry
Wed Jun 20 00:00:00 EDT 2018
Anti-inflammatory Effects of the Octapeptide NAP in Human Microbiota-Associated Mice Suffering from Subacute Ileitis.
European journal of microbiology & immunology
Escher U,Giladi E,Dunay IR,Bereswill S,Gozes I,Heimesaat MM
Published figure using CD45R (B220) monoclonal antibody (Product # 13-0452-82) in Immunohistochemistry (Paraffin)
Mon Jun 25 00:00:00 EDT 2018
Dysregulated TRAF3 and BCL2 Expression Promotes Multiple Classes of Mature Non-hodgkin B Cell Lymphoma in Mice.
Frontiers in immunology
Perez-Chacon G,Adrados M,Vallejo-Cremades MT,Lefebvre S,Reed JC,Zapata JM
Published figure using CD45R (B220) monoclonal antibody (Product # 13-0452-82) in Flow Cytometry
Fri Oct 25 00:00:00 EDT 2019
ATF3 Sustains IL-22-Induced STAT3 Phosphorylation to Maintain Mucosal Immunity Through Inhibiting Phosphatases.
Frontiers in immunology
Glal D,Sudhakar JN,Lu HH,Liu MC,Chiang HY,Liu YC,Cheng CF,Shui JW
Published figure using CD45R (B220) monoclonal antibody (Product # 13-0452-82) in Flow Cytometry
Thu Sep 26 00:00:00 EDT 2019
Spred1 Safeguards Hematopoietic Homeostasis against Diet-Induced Systemic Stress.
Cell stem cell
Tadokoro Y,Hoshii T,Yamazaki S,Eto K,Ema H,Kobayashi M,Ueno M,Ohta K,Arai Y,Hara E,Harada K,Oshima M,Oshima H,Arai F,Yoshimura A,Nakauchi H,Hirao A
13-0452-82 was used in Flow Cytometry to demonstrate the involvement of diet-induced stress on hematopoietic stem cell self-renewal.
Thu May 03 00:00:00 EDT 2018
Hematopoietic stem cells can differentiate into restricted myeloid progenitors before cell division in mice.
Nature communications
Grinenko T,Eugster A,Thielecke L,Ramasz B,Krüger A,Dietz S,Glauche I,Gerbaulet A,von Bonin M,Basak O,Clevers H,Chavakis T,Wielockx B
13-0452 was used in Flow cytometry/Cell sorting to study the mechanisms that control fate decision in adult haematopoietic stem cells.s.
Tue May 15 00:00:00 EDT 2018
A stochastic epigenetic switch controls the dynamics of T-cell lineage commitment.
eLife
Ng KK,Yui MA,Mehta A,Siu S,Irwin B,Pease S,Hirose S,Elowitz MB,Rothenberg EV,Kueh HY
13-0452 was used in Flow cytometry/Cell sorting to study the activation of Bcl11b, which controls T-cell fate commitment.
Tue Nov 20 00:00:00 EST 2018
LaminA/C regulates epigenetic and chromatin architecture changes upon aging of hematopoietic stem cells.
Genome biology
Grigoryan A,Guidi N,Senger K,Liehr T,Soller K,Marka G,Vollmer A,Markaki Y,Leonhardt H,Buske C,Lipka DB,Plass C,Zheng Y,Mulaw MA,Geiger H,Florian MC
13-0452 was used in Flow cytometry/Cell sorting to show that not all histone modifications display a polar localization and that a reduction in H4K16ac amount and loss of epipolarity are specific to aged HSCs.
Wed Nov 07 00:00:00 EST 2018
Epigenetic Restoration of Fetal-like IGF1 Signaling Inhibits Leukemia Stem Cell Activity.
Cell stem cell
Giambra V,Gusscott S,Gracias D,Song R,Lam SH,Panelli P,Tyshchenko K,Jenkins CE,Hoofd C,Lorzadeh A,Carles A,Hirst M,Eaves CJ,Weng AP
13-0452-82 was used in Flow Cytometry to demonstrate that resurrecting dormant fetal programs in adult cells may represent an alternate therapeutic approach in human cancer.
Thu Nov 01 00:00:00 EDT 2018
The orphan nuclear receptor EAR-2 (NR2F6) inhibits hematopoietic cell differentiation and induces myeloid dysplasia in vivo.
Biomarker research
Ichim CV,Dervovic DD,Chan LSA,Robertson CJ,Chesney A,Reis MD,Wells RA
Wed Mar 30 00:00:00 EDT 2022
Age-specific biological and molecular profiling distinguishes paediatric from adult acute myeloid leukaemias.
Nature communications
Chaudhury S,O'Connor C,Cañete A,Bittencourt-Silvestre J,Sarrou E,Prendergast Á,Choi J,Johnston P,Wells CA,Gibson B,Keeshan K
13-0452 was used in Flow cytometry/Cell sorting to study paediatric acute myeloid leukaemia biology, and provide murine models that offer the potential for developing paediatric specific therapeutic strategies.
Tue Dec 11 00:00:00 EST 2018
TGF-β1 Negatively Regulates the Number and Function of Hematopoietic Stem Cells.
Stem cell reports
Wang X,Dong F,Zhang S,Yang W,Yu W,Wang Z,Zhang S,Wang J,Ma S,Wu P,Gao Y,Dong J,Tang F,Cheng T,Ema H
13-0452 was used in Flow cytometry/Cell sorting to examine the effect of transforming growth factor Β1 on haematopoietic stem cell function.
Tue Jul 10 00:00:00 EDT 2018
Non-coding Transcription Instructs Chromatin Folding and Compartmentalization to Dictate Enhancer-Promoter Communication and T Cell Fate.
Cell
Isoda T,Moore AJ,He Z,Chandra V,Aida M,Denholtz M,Piet van Hamburg J,Fisch KM,Chang AN,Fahl SP,Wiest DL,Murre C
13-0452 was used in Flow cytometry/Cell sorting to study the repositioning of the Bcl11b enhancer to dictate the fate of developing T cells.
Thu Sep 21 00:00:00 EDT 2017
Vitamin A-Retinoic Acid Signaling Regulates Hematopoietic Stem Cell Dormancy.
Cell
Cabezas-Wallscheid N,Buettner F,Sommerkamp P,Klimmeck D,Ladel L,Thalheimer FB,Pastor-Flores D,Roma LP,Renders S,Zeisberger P,Przybylla A,Schönberger K,Scognamiglio R,Altamura S,Florian CM,Fawaz M,Vonficht D,Tesio M,Collier P,Pavlinic D,Geiger H,Schroeder T,Benes V,Dick TP,Rieger MA,Stegle O,Trumpp A
13-0452 was used in Flow cytometry/Cell sorting to highlight the impact of dietary vitamin A on the regulation of cell-cycle-mediated stem cell plasticity.
Thu May 18 00:00:00 EDT 2017
Differential cytokine contributions of perivascular haematopoietic stem cell niches.
Nature cell biology
Asada N,Kunisaki Y,Pierce H,Wang Z,Fernandez NF,Birbrair A,Ma'ayan A,Frenette PS
Published figure using CD45R (B220) monoclonal antibody (Product # 13-0452-82) in Flow Cytometry
Wed Mar 01 00:00:00 EST 2017
AMP-Activated Protein Kinase α2 in Neutrophils Regulates Vascular Repair via Hypoxia-Inducible Factor-1α and a Network of Proteins Affecting Metabolism and Apoptosis.
Circulation research
Abdel Malik R,Zippel N,Frömel T,Heidler J,Zukunft S,Walzog B,Ansari N,Pampaloni F,Wingert S,Rieger MA,Wittig I,Fisslthaler B,Fleming I
13-0452 was used in Flow cytometry/Cell sorting to elucidate the role of the AMPKa2 catalytic subunit in vascular repair following ischemia.
Fri Jan 06 00:00:00 EST 2017
Combined antiangiogenic and anti-PD-L1 therapy stimulates tumor immunity through HEV formation.
Science translational medicine
Allen E,Jabouille A,Rivera LB,Lodewijckx I,Missiaen R,Steri V,Feyen K,Tawney J,Hanahan D,Michael IP,Bergers G
Published figure using CD45R (B220) monoclonal antibody (Product # 13-0452-82) in Flow Cytometry
Wed Apr 12 00:00:00 EDT 2017
Epithelial Fli1 deficiency drives systemic autoimmunity and fibrosis: Possible roles in scleroderma.
The Journal of experimental medicine
Takahashi T,Asano Y,Sugawara K,Yamashita T,Nakamura K,Saigusa R,Ichimura Y,Toyama T,Taniguchi T,Akamata K,Noda S,Yoshizaki A,Tsuruta D,Trojanowska M,Sato S
Published figure using CD45R (B220) monoclonal antibody (Product # 13-0452-82) in Flow Cytometry
Mon Apr 03 00:00:00 EDT 2017
Epithelial Fli1 deficiency drives systemic autoimmunity and fibrosis: Possible roles in scleroderma.
The Journal of experimental medicine
Takahashi T,Asano Y,Sugawara K,Yamashita T,Nakamura K,Saigusa R,Ichimura Y,Toyama T,Taniguchi T,Akamata K,Noda S,Yoshizaki A,Tsuruta D,Trojanowska M,Sato S
Published figure using CD45R (B220) monoclonal antibody (Product # 13-0452-82) in Flow Cytometry
Mon Apr 03 00:00:00 EDT 2017
Pre/pro-B cells generate macrophage populations during homeostasis and inflammation.
Proceedings of the National Academy of Sciences of the United States of America
Audzevich T,Bashford-Rogers R,Mabbott NA,Frampton D,Freeman TC,Potocnik A,Kellam P,Gilroy DW
13-0452 was used in Flow cytometry/Cell sorting to study the developmental plasticity of immature B cells and their role as the source of tissue resident macrophages.
Tue May 16 00:00:00 EDT 2017
Chronic Plasmodium chabaudi Infection Generates CD4 Memory T Cells with Increased T Cell Receptor Sensitivity but Poor Secondary Expansion and Increased Apoptosis.
Infection and immunity
Opata MM,Stephens R
13-0452 was used in Flow cytometry/Cell sorting to determine the functional capacity of CD4 T cells generated by chronic infection by reexposure to parasite.
Wed Mar 01 00:00:00 EST 2017
EZH2 enables germinal centre formation through epigenetic silencing of CDKN1A and an Rb-E2F1 feedback loop.
Nature communications
Béguelin W,Rivas MA,Calvo Fernández MT,Teater M,Purwada A,Redmond D,Shen H,Challman MF,Elemento O,Singh A,Melnick AM
Published figure using CD45R (B220) monoclonal antibody (Product # 13-0452-82) in Flow Cytometry
Thu Oct 12 00:00:00 EDT 2017
DNA-binding of the Tet-transactivator curtails antigen-induced lymphocyte activation in mice.
Nature communications
Ottina E,Peperzak V,Schoeler K,Carrington E,Sgonc R,Pellegrini M,Preston S,Herold MJ,Strasser A,Villunger A
Published figure using CD45R (B220) monoclonal antibody (Product # 13-0452-82) in Flow Cytometry
Wed Oct 18 00:00:00 EDT 2017
The Interleukin (IL)-1R1 pathway is a critical negative regulator of PyMT-mediated mammary tumorigenesis and pulmonary metastasis.
Oncoimmunology
Dagenais M,Dupaul-Chicoine J,Douglas T,Champagne C,Morizot A,Saleh M
Published figure using CD45R (B220) monoclonal antibody (Product # 13-0452-82) in Flow Cytometry
Tue Jan 12 00:00:00 EST 2021
Irgm1 coordinately regulates autoimmunity and host defense at select mucosal surfaces.
JCI insight
Azzam KM,Madenspacher JH,Cain DW,Lai L,Gowdy KM,Rai P,Janardhan K,Clayton N,Cunningham W,Jensen H,Patel PS,Kearney JF,Taylor GA,Fessler MB
Published figure using CD45R (B220) monoclonal antibody (Product # 13-0452-82) in Flow Cytometry
Thu Aug 17 00:00:00 EDT 2017
Multiple functional therapeutic effects of TnP: A small stable synthetic peptide derived from fish venom in a mouse model of multiple sclerosis.
PloS one
Komegae EN,Souza TA,Grund LZ,Lima C,Lopes-Ferreira M
Published figure using CD45R (B220) monoclonal antibody (Product # 13-0452-82) in Flow Cytometry
Thu Aug 17 00:00:00 EDT 2017
Understanding Hematopoietic Stem Cell Development through Functional Correlation of Their Proliferative Status with the Intra-aortic Cluster Architecture.
Stem cell reports
Batsivari A,Rybtsov S,Souilhol C,Binagui-Casas A,Hills D,Zhao S,Travers P,Medvinsky A
13-0452 was used in Flow cytometry/Cell sorting to observe time-specific changes in intra-aortic hematopoietic clusters corresponding to HSC maturation stages.
Tue Jun 06 00:00:00 EDT 2017
Mutant U2AF1-expressing cells are sensitive to pharmacological modulation of the spliceosome.
Nature communications
Shirai CL,White BS,Tripathi M,Tapia R,Ley JN,Ndonwi M,Kim S,Shao J,Carver A,Saez B,Fulton RS,Fronick C,O'Laughlin M,Lagisetti C,Webb TR,Graubert TA,Walter MJ
13-0452 was used in Flow cytometry/Cell sorting to suggest a potential for treating haematological cancers harbouring U2AF1 mutations with pre-mRNA splicing modulators like sudemycins.
Mon Jan 09 00:00:00 EST 2017
Hematopoietic Stem Cells Count and Remember Self-Renewal Divisions.
Cell
Bernitz JM,Kim HS,MacArthur B,Sieburg H,Moore K
13-0452-82 was used in Flow Cytometry to suggest that HSCs accumulate discrete memory stages over their divisional history and identify cellular memory in HSC aging.
Thu Nov 17 00:00:00 EST 2016
IL-23 induced in keratinocytes by endogenous TLR4 ligands polarizes dendritic cells to drive IL-22 responses to skin immunization.
The Journal of experimental medicine
Yoon J,Leyva-Castillo JM,Wang G,Galand C,Oyoshi MK,Kumar L,Hoff S,He R,Chervonsky A,Oppenheim JJ,Kuchroo VK,van den Brink MR,Malefyt Rde W,Tessier PA,Fuhlbrigge R,Rosenstiel P,Terhorst C,Murphy G,Geha RS
13-0452 was used in Flow cytometry/Cell sorting to elucidate the mechanisms behind DC-derived IL-23 in a model of skin inflammation.
Mon Sep 19 00:00:00 EDT 2016
CD8+ T cells drive autoimmune hematopoietic stem cell dysfunction and bone marrow failure.
Journal of autoimmunity
Gravano DM,Al-Kuhlani M,Davini D,Sanders PD,Manilay JO,Hoyer KK
13-0452 was used in Flow cytometry/Cell sorting to investigate whether CD8+ T cells play a non-redundant role in driving bone marrow failure.
Thu Dec 01 00:00:00 EST 2016
Bmp signaling in colonic mesenchyme regulates stromal microenvironment and protects from polyposis initiation.
International journal of cancer
Allaire JM,Roy SA,Ouellet C,Lemieux É,Jones C,Paquet M,Boudreau F,Perreault N
Published figure using CD45R (B220) monoclonal antibody (Product # 13-0452-82) in Immunofluorescence
Wed Jun 01 00:00:00 EDT 2016
Resident T Cells Are Unable To Control Herpes Simplex Virus-1 Activity in the Brain Ependymal Region during Latency.
Journal of immunology (Baltimore, Md. : 1950)
Menendez CM,Jinkins JK,Carr DJ
Published figure using CD45R (B220) monoclonal antibody (Product # 13-0452-82) in Flow Cytometry
Mon Aug 15 00:00:00 EDT 2016
Postnatal lethality and abnormal development of foregut and spleen in Ndrg4 mutant mice.
Biochemical and biophysical research communications
Qu X,Li J,Baldwin HS
Published figure using CD45R (B220) monoclonal antibody (Product # 13-0452-82) in Immunofluorescence
Fri Feb 12 00:00:00 EST 2016
Murine iPSC-Derived Macrophages as a Tool for Disease Modeling of Hereditary Pulmonary Alveolar Proteinosis due to Csf2rb Deficiency.
Stem cell reports
Mucci A,Kunkiel J,Suzuki T,Brennig S,Glage S,Kühnel MP,Ackermann M,Happle C,Kuhn A,Schambach A,Trapnell BC,Hansen G,Moritz T,Lachmann N
Published figure using CD45R (B220) monoclonal antibody (Product # 13-0452-82) in Flow Cytometry
Tue Aug 09 00:00:00 EDT 2016
Affinity and dose of TCR engagement yield proportional enhancer and gene activity in CD4+ T cells.
eLife
Allison KA,Sajti E,Collier JG,Gosselin D,Troutman TD,Stone EL,Hedrick SM,Glass CK
13-0452 was used in Magnetic cell separation to investigate relationship between the strength of antigenic stimulation and the response of mouse CD4+ T cells.
Mon Jul 04 00:00:00 EDT 2016
p38 MAPK Inhibitor Insufficiently Attenuates HSC Senescence Administered Long-Term after 6 Gy Total Body Irradiation in Mice.
International journal of molecular sciences
Lu L,Wang YY,Zhang JL,Li DG,Meng AM
13-0452 was used in Flow cytometry/Cell sorting to investigate the effects of SB203580 on long-term TBI-induced myelosuppression.
Wed Jun 08 00:00:00 EDT 2016
Induction of Suppressor Cells and Increased Tumor Growth following Chronic Psychosocial Stress in Male Mice.
PloS one
Schmidt D,Peterlik D,Reber SO,Lechner A,Männel DN
13-0452 was used in Flow cytometry/Cell sorting to observe the immunological effects of chronic psychosocial stress in mice.
Fri Aug 18 00:00:00 EDT 2017
Imaging Macrophage and Hematopoietic Progenitor Proliferation in Atherosclerosis.
Circulation research
Ye YX,Calcagno C,Binderup T,Courties G,Keliher EJ,Wojtkiewicz GR,Iwamoto Y,Tang J,Pérez-Medina C,Mani V,Ishino S,Johnbeck CB,Knigge U,Fayad ZA,Libby P,Weissleder R,Tawakol A,Dubey S,Belanger AP,Di Carli MF,Swirski FK,Kjaer A,Mulder WJ,Nahrendorf M
13-0452 was used in Flow cytometry/Cell sorting to perform (18)F-FLT positron emission tomography-computed tomography was performed in mice, rabbits, and humans with atherosclerosis.
Fri Oct 23 00:00:00 EDT 2015
Aging-associated inflammation promotes selection for adaptive oncogenic events in B cell progenitors.
The Journal of clinical investigation
Henry CJ,Casás-Selves M,Kim J,Zaberezhnyy V,Aghili L,Daniel AE,Jimenez L,Azam T,McNamee EN,Clambey ET,Klawitter J,Serkova NJ,Tan AC,Dinarello CA,DeGregori J
Published figure using CD45R (B220) monoclonal antibody (Product # 13-0452-82) in Flow Cytometry
Tue Dec 01 00:00:00 EST 2015
Distinct germinal center selection at local sites shapes memory B cell response to viral escape.
The Journal of experimental medicine
Adachi Y,Onodera T,Yamada Y,Daio R,Tsuiji M,Inoue T,Kobayashi K,Kurosaki T,Ato M,Takahashi Y
13-0452 was used in Flow cytometry/Cell sorting to investigate the cellular events dictating the cross-reactive memory B cell responses, showing that distinct germinal center selection at local sites shapes response to viral escape.
Mon Sep 21 00:00:00 EDT 2015
Distinct germinal center selection at local sites shapes memory B cell response to viral escape.
The Journal of experimental medicine
Adachi Y,Onodera T,Yamada Y,Daio R,Tsuiji M,Inoue T,Kobayashi K,Kurosaki T,Ato M,Takahashi Y
13-0452 was used in Flow cytometry/Cell sorting to investigate the cellular events dictating the cross-reactive memory B cell responses, showing that distinct germinal center selection at local sites shapes response to viral escape.
Mon Sep 21 00:00:00 EDT 2015
MHC-mismatched mixed chimerism augments thymic regulatory T-cell production and prevents relapse of EAE in mice.
Proceedings of the National Academy of Sciences of the United States of America
Wu L,Li N,Zhang M,Xue SL,Cassady K,Lin Q,Riggs AD,Zeng D
Published figure using CD45R (B220) monoclonal antibody (Product # 13-0452-82) in Immunofluorescence
Tue Dec 29 00:00:00 EST 2015
Mitochondrial ATP transporter Ant2 depletion impairs erythropoiesis and B lymphopoiesis.
Cell death and differentiation
Cho J,Seo J,Lim CH,Yang L,Shiratsuchi T,Lee MH,Chowdhury RR,Kasahara H,Kim JS,Oh SP,Lee YJ,Terada N
Published figure using CD45R (B220) monoclonal antibody (Product # 13-0452-82) in Flow Cytometry
Tue Sep 01 00:00:00 EDT 2015
The immunosenescence-related gene Zizimin2 is associated with early bone marrow B cell development and marginal zone B cell formation.
Immunity & ageing : I & A
Matsuda T,Yanase S,Takaoka A,Maruyama M
Published figure using CD45R (B220) monoclonal antibody (Product # 13-0452-82) in Immunofluorescence
Mon Mar 02 00:00:00 EST 2015
Frizzled-6 Regulates Hematopoietic Stem/Progenitor Cell Survival and Self-Renewal.
Journal of immunology (Baltimore, Md. : 1950)
Abidin BM,Owusu Kwarteng E,Heinonen KM
13-0452 was used in Flow cytometry/Cell sorting to reveal that Fzd6 has an essential role in HSPC maintenance and survival.
Tue Sep 01 00:00:00 EDT 2015
CCR6-dependent positioning of memory B cells is essential for their ability to mount a recall response to antigen.
Journal of immunology (Baltimore, Md. : 1950)
Elgueta R,Marks E,Nowak E,Menezes S,Benson M,Raman VS,Ortiz C,O'Connell S,Hess H,Lord GM,Noelle R
13-0452 was used in Flow cytometry/Cell sorting to show that antigen-specific memory B cells express heightened levels of CCR6 and display an increased chemotactic response to the CCR6 ligand, CCL20, when compared to naïve B cells.
Thu Jan 15 00:00:00 EST 2015
DGCR14 induces Il17a gene expression through the RORγ/BAZ1B/RSKS2 complex.
Molecular and cellular biology
Takada I
13-0452 was used in Magnetic cell separation to show the roles of DGCR14, RSK2, and BAZ1B in the transcriptional regulation of Il17a mRNA during TH17 cell differentiation.
Thu Jan 01 00:00:00 EST 2015
Inhibition of the CXCL12/CXCR4 chemokine axis with AMD3100, a CXCR4 small molecule inhibitor, worsens murine hepatic injury.
Hepatology research : the official journal of the Japan Society of Hepatology
Saiman Y,Jiao J,Fiel MI,Friedman SL,Aloman C,Bansal MB
13-0452 was used in Flow cytometry/Cell sorting to suggest that inhibition of the CXCR4/CXCL12 chemokine axis is injurious through modulation of the hepatic inflammatory response.
Wed Jul 01 00:00:00 EDT 2015
Comparison of tamoxifen and letrozole response in mammary preneoplasia of ER and aromatase overexpressing mice defines an immune-associated gene signature linked to tamoxifen resistance.
Carcinogenesis
Dabydeen SA,Kang K,Díaz-Cruz ES,Alamri A,Axelrod ML,Bouker KB,Al-Kharboosh R,Clarke R,Hennighausen L,Furth PA
Published figure using CD45R (B220) monoclonal antibody (Product # 13-0452-82) in Immunohistochemistry
Thu Jan 01 00:00:00 EST 2015
Limited miR-17-92 overexpression drives hematologic malignancies.
Leukemia research
Danielson LS,Reavie L,Coussens M,Davalos V,Castillo-Martin M,Guijarro MV,Coffre M,Cordon-Cardo C,Aifantis I,Ibrahim S,Liu C,Koralov SB,Hernando E
Published figure using CD45R (B220) monoclonal antibody (Product # 13-0452-82) in Immunohistochemistry
Sun Mar 01 00:00:00 EST 2015
Endothelial Gata5 transcription factor regulates blood pressure.
Nature communications
Messaoudi S,He Y,Gutsol A,Wight A,Hébert RL,Vilmundarson RO,Makrigiannis AP,Chalmers J,Hamet P,Tremblay J,McPherson R,Stewart AFR,Touyz RM,Nemer M
Published figure using CD45R (B220) monoclonal antibody (Product # 13-0452-82) in Flow Cytometry
Mon Nov 30 00:00:00 EST 2015
Disruption of p21-activated kinase 1 gene diminishes atherosclerosis in apolipoprotein E-deficient mice.
Nature communications
Singh NK,Kotla S,Dyukova E,Traylor JG,Orr AW,Chernoff J,Marion TN,Rao GN
Published figure using CD45R (B220) monoclonal antibody (Product # 13-0452-82) in Flow Cytometry
Wed Jun 24 00:00:00 EDT 2015
Disease severity and mortality can be independently regulated in a mouse model of experimental graft versus host disease.
PloS one
Galvani RG,Lemos R,Areal RB,Salvador PA,Zamboni DS,Wanderley JL,Bonomo A
13-0452 was used in Magnetic cell separation to investigate the exact cause of death in graft versus host disease, showing that disease severity and mortality can be independently regulated.
Mon Oct 19 00:00:00 EDT 2015
IFN-γ and IL-21 Double Producing T Cells Are Bcl6-Independent and Survive into the Memory Phase in Plasmodium chabaudi Infection.
PloS one
Carpio VH,Opata MM,Montañez ME,Banerjee PP,Dent AL,Stephens R
13-0452 was used in Flow cytometry/Cell sorting to elucidate the lineage of a specific Ifng+ CD4 T cell subset generated during Plasmodium chabaudi infection in mice.
Sun Jun 26 00:00:00 EDT 2016
Infection mobilizes hematopoietic stem cells through cooperative NOD-like receptor and Toll-like receptor signaling.
Cell host & microbe
Burberry A,Zeng MY,Ding L,Wicks I,Inohara N,Morrison SJ,Núñez G
13-0452 was used in Flow cytometry/Cell sorting to investigate how infection mobilises hematopoietic stem cells through cooperative NOD-like receptor and Toll-like receptor signalling.
Wed Jun 11 00:00:00 EDT 2014
Combined MEK and JAK inhibition abrogates murine myeloproliferative neoplasm.
The Journal of clinical investigation
Kong G,Wunderlich M,Yang D,Ranheim EA,Young KH,Wang J,Chang YI,Du J,Liu Y,Tey SR,Zhang X,Juckett M,Mattison R,Damnernsawad A,Zhang J,Mulloy JC,Zhang J
13-0452 was used in Flow cytometry/Cell sorting to investigate the effect of combined targeting of MEK/ERK and JAK/STAT signalling on the murine myeloproliferative neoplasm.
Sun Jun 01 00:00:00 EDT 2014
Bronchial epithelial injury in the context of alloimmunity promotes lymphocytic bronchiolitis through hyaluronan expression.
American journal of physiology. Lung cellular and molecular physiology
Stober VP,Szczesniak C,Childress Q,Heise RL,Bortner C,Hollingsworth JW,Neuringer IP,Palmer SM,Garantziotis S
13-0452 was used in Flow cytometry/Cell sorting to study the effect of sterile bronchial epithelial injuries on alloimmunity.
Sun Jun 01 00:00:00 EDT 2014
Transcription elongation factor ELL2 drives Ig secretory-specific mRNA production and the unfolded protein response.
Journal of immunology (Baltimore, Md. : 1950)
Park KS,Bayles I,Szlachta-McGinn A,Paul J,Boiko J,Santos P,Liu J,Wang Z,Borghesi L,Milcarek C
Published figure using CD45R (B220) monoclonal antibody (Product # 13-0452-82) in Flow Cytometry
Sat Nov 01 00:00:00 EDT 2014
IκBε is a key regulator of B cell expansion by providing negative feedback on cRel and RelA in a stimulus-specific manner.
Journal of immunology (Baltimore, Md. : 1950)
Alves BN,Tsui R,Almaden J,Shokhirev MN,Davis-Turak J,Fujimoto J,Birnbaum H,Ponomarenko J,Hoffmann A
Published figure using CD45R (B220) monoclonal antibody (Product # 13-0452-82) in Flow Cytometry
Tue Apr 01 00:00:00 EDT 2014
Rhof promotes murine marginal zone B cell development.
Nagoya journal of medical science
Kishimoto M,Matsuda T,Yanase S,Katsumi A,Suzuki N,Ikejiri M,Takagi A,Ikawa M,Kojima T,Kunishima S,Kiyoi H,Naoe T,Matsushita T,Maruyama M
Published figure using CD45R (B220) monoclonal antibody (Product # 13-0452-82) in Flow Cytometry
Fri Aug 01 00:00:00 EDT 2014
B-cell-intrinsic hepatitis C virus expression leads to B-cell-lymphomagenesis and induction of NF-κB signalling.
PloS one
Kasama Y,Mizukami T,Kusunoki H,Peveling-Oberhag J,Nishito Y,Ozawa M,Kohara M,Mizuochi T,Tsukiyama-Kohara K
Published figure using CD45R (B220) monoclonal antibody (Product # 13-0452-82) in Immunofluorescence
Mon Dec 22 00:00:00 EST 2014
B-cell-intrinsic hepatitis C virus expression leads to B-cell-lymphomagenesis and induction of NF-κB signalling.
PloS one
Kasama Y,Mizukami T,Kusunoki H,Peveling-Oberhag J,Nishito Y,Ozawa M,Kohara M,Mizuochi T,Tsukiyama-Kohara K
Published figure using CD45R (B220) monoclonal antibody (Product # 13-0452-82) in Immunofluorescence
Mon Dec 22 00:00:00 EST 2014
Gene targeting study reveals unexpected expression of brain-expressed X-linked 2 in endocrine and tissue stem/progenitor cells in mice.
The Journal of biological chemistry
Ito K,Yamazaki S,Yamamoto R,Tajima Y,Yanagida A,Kobayashi T,Kato-Itoh M,Kakuta S,Iwakura Y,Nakauchi H,Kamiya A
13-0452 was used in Flow cytometry/Cell sorting to investigate the precise role and expression pattern of brain-expressed X-linked genes in endocrine and tissue stem/progenitor cells in mice.
Fri Oct 24 00:00:00 EDT 2014
Quantitative assessment of the robustness of next-generation sequencing of antibody variable gene repertoires from immunized mice.
BMC immunology
Greiff V,Menzel U,Haessler U,Cook SC,Friedensohn S,Khan TA,Pogson M,Hellmann I,Reddy ST
13-0452-82 was used in Magnetic cell separation to establish widely applicable experimental and computational guidelines for robust antibody NGS and analysis.
Thu Oct 16 00:00:00 EDT 2014
Arteriolar niches maintain haematopoietic stem cell quiescence.
Nature
Kunisaki Y,Bruns I,Scheiermann C,Ahmed J,Pinho S,Zhang D,Mizoguchi T,Wei Q,Lucas D,Ito K,Mar JC,Bergman A,Frenette PS
13-0452 was used in Flow cytometry/Cell sorting to investigate the spatial localisation of quiescent haematopoietic stem cells in bone marrow, showing that arteriolar niches maintain quiescence.
Thu Oct 31 00:00:00 EDT 2013
Natural IgG antibodies provide innate protection against ficolin-opsonized bacteria.
The EMBO journal
Panda S,Zhang J,Tan NS,Ho B,Ding JL
Published figure using CD45R (B220) monoclonal antibody (Product # 13-0452-82) in Immunofluorescence
Wed Nov 13 00:00:00 EST 2013
Reciprocal effects of rab7 deletion in activated and neglected T cells.
Autophagy
Roy SG,Stevens MW,So L,Edinger AL
Published figure using CD45R (B220) monoclonal antibody (Product # 13-0452-82) in Flow Cytometry
Mon Jul 01 00:00:00 EDT 2013
A component of the mir-17-92 polycistronic oncomir promotes oncogene-dependent apoptosis.
eLife
Olive V,Sabio E,Bennett MJ,De Jong CS,Biton A,McGann JC,Greaney SK,Sodir NM,Zhou AY,Balakrishnan A,Foth M,Luftig MA,Goga A,Speed TP,Xuan Z,Evan GI,Wan Y,Minella AC,He L
Published figure using CD45R (B220) monoclonal antibody (Product # 13-0452-82) in Immunohistochemistry
Tue Oct 15 00:00:00 EDT 2013
Cbx4 regulates the proliferation of thymic epithelial cells and thymus function.
Development (Cambridge, England)
Liu B,Liu YF,Du YR,Mardaryev AN,Yang W,Chen H,Xu ZM,Xu CQ,Zhang XR,Botchkarev VA,Zhang Y,Xu GL
Published figure using CD45R (B220) monoclonal antibody (Product # 13-0452-82) in Immunofluorescence
Fri Feb 01 00:00:00 EST 2013
Cbx4 regulates the proliferation of thymic epithelial cells and thymus function.
Development (Cambridge, England)
Liu B,Liu YF,Du YR,Mardaryev AN,Yang W,Chen H,Xu ZM,Xu CQ,Zhang XR,Botchkarev VA,Zhang Y,Xu GL
Published figure using CD45R (B220) monoclonal antibody (Product # 13-0452-82) in Immunofluorescence
Fri Feb 01 00:00:00 EST 2013
Sialyltransferase ST3Gal-III regulates Siglec-F ligand formation and eosinophilic lung inflammation in mice.
Journal of immunology (Baltimore, Md. : 1950)
Suzukawa M,Miller M,Rosenthal P,Cho JY,Doherty TA,Varki A,Broide D
13-0452 was used in Flow cytometry/Cell sorting to study the regulated murine expression of Siglec-F ligand in immune and lung airway epithelial cells.
Sat Jun 15 00:00:00 EDT 2013
Enhancing T lineage production in aged mice: a novel function of Foxn1 in the bone marrow niche.
Journal of immunology (Baltimore, Md. : 1950)
Zook EC,Zhang S,Gerstein RM,Witte PL,Le PT
13-0452 was used in Flow cytometry/Cell sorting to report that Foxn1 is expressed in wild-type BM and overexpressed in Foxn1Tg.
Sun Dec 01 00:00:00 EST 2013
Focal adhesion kinase regulates the localization and retention of pro-B cells in bone marrow microenvironments.
Journal of immunology (Baltimore, Md. : 1950)
Park SY,Wolfram P,Canty K,Harley B,Nombela-Arrieta C,Pivarnik G,Manis J,Beggs HE,Silberstein LE
13-0452 was used in Immunofluorescence in immunohistochemistry on frozen tissues to study the importance of focal adhesion kinase in regulating pro-B cell homeostasis and maintenance of their spatial distribution in bone marrow niches.
Fri Feb 01 00:00:00 EST 2013
Scmh1 has E3 ubiquitin ligase activity for geminin and histone H2A and regulates geminin stability directly or indirectly via transcriptional repression of Hoxa9 and Hoxb4.
Molecular and cellular biology
Yasunaga S,Ohtsubo M,Ohno Y,Saeki K,Kurogi T,Tanaka-Okamoto M,Ishizaki H,Shirai M,Mihara K,Brock HW,Miyoshi J,Takihara Y
13-0452 was used in Flow cytometry/Cell sorting to investigate the effects of Scmh1 on Geminin and Histone H2A, and the mechanisms therein.
Fri Feb 01 00:00:00 EST 2013
Flow cytometry analysis of murine hematopoietic stem cells.
Cytometry. Part A : the journal of the International Society for Analytical Cytology
Mayle A,Luo M,Jeong M,Goodell MA
13-0452 was used in Flow cytometry/Cell sorting to discuss methods for rapid flow cytometric analysis of peripheral blood cell types and novel strategies for working with rare cell populations such as hematopoietic stem cells in the analysis of cell cycle status by BrdU, Ki-67, and Pyronin Y staining.
Tue Jan 01 00:00:00 EST 2013
Antigen-loaded pH-sensitive hydrogel microparticles are taken up by dendritic cells with no requirement for targeting antibodies.
Integrative biology : quantitative biosciences from nano to macro
Ruff LE,Mahmoud EA,Sankaranarayanan J,Morachis JM,Katayama CD,Corr M,Hedrick SM,Almutairi A
13-0452-82 was used in Immunopurification to characterise the uptake of antigen-loaded, pH-sensitive hydrogel microparticles by bone marrow-derived dendritic cells.
Tue Jan 01 00:00:00 EST 2013
Neuronal and nonneuronal cholinergic structures in the mouse gastrointestinal tract and spleen.
The Journal of comparative neurology
Gautron L,Rutkowski JM,Burton MD,Wei W,Wan Y,Elmquist JK
Published figure using CD45R (B220) monoclonal antibody (Product # 13-0452-82) in Immunofluorescence
Fri Nov 01 00:00:00 EDT 2013
Inhibiting TGFβ1 has a protective effect on mouse bone marrow suppression following ionizing radiation exposure in vitro.
Journal of radiation research
Zhang H,Wang YA,Meng A,Yan H,Wang X,Niu J,Li J,Wang H
13-0452 was used in Flow cytometry/Cell sorting to examine if the TGF1 inhibitor, SB431542, can mitigate ionizing radiation-induced bone marrow suppression, showing that inhibition has a protective effect.
Mon Jul 01 00:00:00 EDT 2013
TDP2-dependent non-homologous end-joining protects against topoisomerase II-induced DNA breaks and genome instability in cells and in vivo.
PLoS genetics
Gómez-Herreros F,Romero-Granados R,Zeng Z,Alvarez-Quilón A,Quintero C,Ju L,Umans L,Vermeire L,Huylebroeck D,Caldecott KW,Cortés-Ledesma F
Published figure using CD45R (B220) monoclonal antibody (Product # 13-0452-82) in Flow Cytometry
Thu Jun 13 00:00:00 EDT 2013
Properties of immature myeloid progenitors with nitric-oxide-dependent immunosuppressive activity isolated from bone marrow of tumor-free mice.
PloS one
Forghani P,Harris W,Giver CR,Mirshafiey A,Galipeau J,Waller EK
13-0452 was used in Flow cytometry/Cell sorting to determine the role of immature myeloid cells in regulating T-cell activation and proliferation in bone marrow.
Thu Jan 23 00:00:00 EST 2014
Biphenotypic B-lymphoid/myeloid cells expressing low levels of Pax5: potential targets of BAL development.
Blood
Simmons S,Knoll M,Drewell C,Wolf I,Mollenkopf HJ,Bouquet C,Melchers F
13-0452 was used in Flow cytometry/Cell sorting to investigate how variation in Pax5 expression influences hematopoietic development, showing that biphenotypic B-lymphoid/myeloid cells expressing low levels of Pax5 could be targets for BAL.
Thu Nov 01 00:00:00 EDT 2012
Notch, Id2, and RORγt sequentially orchestrate the fetal development of lymphoid tissue inducer cells.
The Journal of experimental medicine
Cherrier M,Sawa S,Eberl G
13-0452 was used in Magnetic cell separation to investigate the development of lymphoid tissue inducer (LTi) cells from common lymphoid progenitors (CLPs) in the fetal liver, showing that sequential changes in expression of Notch, Id2, and RORγt orchestrate the development of LTi cells.
Mon Apr 09 00:00:00 EDT 2012
Molecular imaging of very late antigen-4 (α4β1 integrin) in the premetastatic niche.
Journal of nuclear medicine : official publication, Society of Nuclear Medicine
Shokeen M,Zheleznyak A,Wilson JM,Jiang M,Liu R,Ferdani R,Lam KS,Schwarz JK,Anderson CJ
13-0452 was used in Flow cytometry/Cell sorting to study bone marrow-derived cellular expression of VEGFR1 and VLA-4 in the development of a premetastatic niche.
Tue May 01 00:00:00 EDT 2012
Critical role of B cell lymphoma 10 in BAFF-regulated NF-κB activation and survival of anergic B cells.
Journal of immunology (Baltimore, Md. : 1950)
Yu M,Chen Y,He Y,Podd A,Fu G,Wright JA,Kleiman E,Khan WN,Wen R,Wang D
Published figure using CD45R (B220) monoclonal antibody (Product # 13-0452-82) in Flow Cytometry
Sat Dec 01 00:00:00 EST 2012
Activation-induced cytidine deaminase-initiated off-target DNA breaks are detected and resolved during S phase.
Journal of immunology (Baltimore, Md. : 1950)
Hasham MG,Snow KJ,Donghia NM,Branca JA,Lessard MD,Stavnezer J,Shopland LS,Mills KD
Published figure using CD45R (B220) monoclonal antibody (Product # 13-0452-82) in Flow Cytometry
Sat Sep 01 00:00:00 EDT 2012
Differential requirements for IRF-2 in generation of CD1d-independent T cells bearing NK cell receptors.
Journal of immunology (Baltimore, Md. : 1950)
Notake T,Horisawa S,Sanjo H,Miyagawa S,Hida S,Taki S
13-0452 was used in Flow cytometry/Cell sorting to investigate the mechanisms behind the generation and function of NKR(+) T cells.
Tue May 15 00:00:00 EDT 2012
Nuclear export of the NF-κB inhibitor IκBα is required for proper B cell and secondary lymphoid tissue formation.
Immunity
Wuerzberger-Davis SM,Chen Y,Yang DT,Kearns JD,Bates PW,Lynch C,Ladell NC,Yu M,Podd A,Zeng H,Huang TT,Wen R,Hoffmann A,Wang D,Miyamoto S
Published figure using CD45R (B220) monoclonal antibody (Product # 13-0452-82) in Flow Cytometry
Fri Feb 25 00:00:00 EST 2011
Nuclear export of the NF-κB inhibitor IκBα is required for proper B cell and secondary lymphoid tissue formation.
Immunity
Wuerzberger-Davis SM,Chen Y,Yang DT,Kearns JD,Bates PW,Lynch C,Ladell NC,Yu M,Podd A,Zeng H,Huang TT,Wen R,Hoffmann A,Wang D,Miyamoto S
Published figure using CD45R (B220) monoclonal antibody (Product # 13-0452-82) in Flow Cytometry
Fri Feb 25 00:00:00 EST 2011
Transcription factor Smad-independent T helper 17 cell induction by transforming-growth factor-β is mediated by suppression of eomesodermin.
Immunity
Ichiyama K,Sekiya T,Inoue N,Tamiya T,Kashiwagi I,Kimura A,Morita R,Muto G,Shichita T,Takahashi R,Yoshimura A
13-0452 was used in Magnetic cell separation to investigate the molecular mechanisms by which TGF-beta allows Th17 cell differentiation via Smad-independent mechanisms, showing that Eomesodermin is suppressed by TGF-beta via the JNK pathway allowing differentiation.
Fri May 27 00:00:00 EDT 2011
Chronic IFN-γ production in mice induces anemia by reducing erythrocyte life span and inhibiting erythropoiesis through an IRF-1/PU.1 axis.
Blood
Libregts SF,Gutiérrez L,de Bruin AM,Wensveen FM,Papadopoulos P,van Ijcken W,Ozgür Z,Philipsen S,Nolte MA
13-0452 was used in Flow cytometry/Cell sorting to reveal a molecular mechanism by which chronic exposure to IFN-γ induces expression of IRF-1 and ultimately induces anaemia.
Thu Sep 01 00:00:00 EDT 2011
Emergency granulopoiesis promotes neutrophil-dendritic cell encounters that prevent mouse lung allograft acceptance.
Blood
Kreisel D,Sugimoto S,Zhu J,Nava R,Li W,Okazaki M,Yamamoto S,Ibrahim M,Huang HJ,Toth KA,Ritter JH,Krupnick AS,Miller MJ,Gelman AE
13-0452 was used in Magnetic cell separation to identify granulopoiesis-mediated augmentation of alloimmunity as a novel link between innate and adaptive immune responses after organ transplantation.
Thu Dec 01 00:00:00 EST 2011
Defective hematopoietic stem cell and lymphoid progenitor development in the Ts65Dn mouse model of Down syndrome: potential role of oxidative stress.
Antioxidants & redox signaling
Lorenzo LP,Chen H,Shatynski KE,Clark S,Yuan R,Harrison DE,Yarowsky PJ,Williams MS
13-0452 was used in Flow cytometry/Cell sorting to identify a link between oxidative stress and diminished IL-7Rα expression and function associated with defective haematologic development in a DS mouse model.
Sat Oct 15 00:00:00 EDT 2011
The central role of CD30L/CD30 interactions in allergic rhinitis pathogenesis in mice.
European journal of immunology
Fuchiwaki T,Sun X,Fujimura K,Yamada H,Shibata K,Muta H,Podack ER,Kawauchi H,Yoshikai Y
13-0452 was used in Flow cytometry/Cell sorting to examine the role of CD30 ligand in allergic rhinitis.
Sat Oct 01 00:00:00 EDT 2011
Cellular competition independent of BAFF/B lymphocyte stimulator results in low frequency of an autoreactive clonotype in mature polyclonal B cell compartments.
Journal of immunology (Baltimore, Md. : 1950)
Nikbakht N,Migone TS,Ward CP,Manser T
13-0452 was used in Flow cytometry/Cell sorting to investigate the role of the peripheral B cell pro-survival cytokine BAFF/BLyS in the regulation of immunological tolerance and autoreactive cells.
Fri Jul 01 00:00:00 EDT 2011
Hepatic stellate cells function as regulatory bystanders.
Journal of immunology (Baltimore, Md. : 1950)
Ichikawa S,Mucida D,Tyznik AJ,Kronenberg M,Cheroutre H
13-0452 was used in Magnetic cell separation to suggest that HSC can function as regulatory bystanders, and therefore, by promoting Tregs and suppressing Th17 differentiation, they might represent key players in the mechanism that drives liver-induced tolerance.
Sun May 15 00:00:00 EDT 2011
Involvement of twisted gastrulation in T cell-independent plasma cell production.
Journal of immunology (Baltimore, Md. : 1950)
Tsalavos S,Segklia K,Passa O,Petryk A,O'Connor MB,Graf D
13-0452 was used in Flow cytometry/Cell sorting to report that Twisted gastrulation (TWSG1), is expressed in activated B cells and regulates T-independent B cell responses.
Wed Jun 15 00:00:00 EDT 2011
IL-1β and TNFα-initiated IL-6-STAT3 pathway is critical in mediating inflammatory cytokines and RANKL expression in inflammatory arthritis.
International immunology
Mori T,Miyamoto T,Yoshida H,Asakawa M,Kawasumi M,Kobayashi T,Morioka H,Chiba K,Toyama Y,Yoshimura A
13-0452 was used in Functional assays to elucidate the role of cytokines in chronic inflammation and joint destruction in rheumatoid arthritis.
Tue Nov 01 00:00:00 EDT 2011
Activation of the aryl hydrocarbon receptor during pregnancy in the mouse alters mammary development through direct effects on stromal and epithelial tissues.
Biology of reproduction
Lew BJ,Manickam R,Lawrence BP
13-0452 was used in Flow cytometry/Cell sorting to determine whether activation of the aryl hydrocarbon receptor (AHR) during pregnancy modulates mammary development.
Wed Jun 01 00:00:00 EDT 2011
PAD4-mediated neutrophil extracellular trap formation is not required for immunity against influenza infection.
PloS one
Hemmers S,Teijaro JR,Arandjelovic S,Mowen KA
Published figure using CD45R (B220) monoclonal antibody (Product # 13-0452-82) in Flow Cytometry
Tue Nov 15 00:00:00 EST 2011
Online nanoflow multidimensional fractionation for high efficiency phosphopeptide analysis.
Molecular & cellular proteomics : MCP
Ficarro SB,Zhang Y,Carrasco-Alfonso MJ,Garg B,Adelmant G,Webber JT,Luckey CJ,Marto JA
13-0452 was used in Flow cytometry/Cell sorting to explore two novel multidimensional fractionation strategies for the gathering of phosphoproteomics data.
Tue Nov 01 00:00:00 EDT 2011
The sensing of environmental stimuli by follicular dendritic cells promotes immunoglobulin A generation in the gut.
Immunity
Suzuki K,Maruya M,Kawamoto S,Sitnik K,Kitamura H,Agace WW,Fagarasan S
13-0452 was used in Flow cytometry/Cell sorting to investigate whether follicular dendritic cells within the germinal centers directly contribute to the IgA production in Peyer's patches, showing that sensing of environmental stimuli promotes IgA production.
Fri Jul 23 00:00:00 EDT 2010
Deletion of the RNA-binding proteins ZFP36L1 and ZFP36L2 leads to perturbed thymic development and T lymphoblastic leukemia.
Nature immunology
Hodson DJ,Janas ML,Galloway A,Bell SE,Andrews S,Li CM,Pannell R,Siebel CW,MacDonald HR,De Keersmaecker K,Ferrando AA,Grutz G,Turner M
13-0452 was used in Flow cytometry/Cell sorting to establish a role for ZFP36L1 and ZFP36L2 during thymocyte development and in the prevention of malignant transformation.
Sun Aug 01 00:00:00 EDT 2010
Peripheral CD103+ dendritic cells form a unified subset developmentally related to CD8alpha+ conventional dendritic cells.
The Journal of experimental medicine
Edelson BT,KC W,Juang R,Kohyama M,Benoit LA,Klekotka PA,Moon C,Albring JC,Ise W,Michael DG,Bhattacharya D,Stappenbeck TS,Holtzman MJ,Sung SS,Murphy TL,Hildner K,Murphy KM
13-0452 was used in Flow cytometry/Cell sorting to study the relationship between nonlymphoid CD103-expressing dendritic cells (DCs) and other DC subsets.
Mon Apr 12 00:00:00 EDT 2010
Dendritic cell (DC)-specific targeting reveals Stat3 as a negative regulator of DC function.
Journal of immunology (Baltimore, Md. : 1950)
Melillo JA,Song L,Bhagat G,Blazquez AB,Plumlee CR,Lee C,Berin C,Reizis B,Schindler C
13-0452 was used in Flow cytometry/Cell sorting to directly examine the role Stat3 plays in regulating dendritic cell activity.
Mon Mar 01 00:00:00 EST 2010
Impaired apoptotic cell clearance in the germinal center by Mer-deficient tingible body macrophages leads to enhanced antibody-forming cell and germinal center responses.
Journal of immunology (Baltimore, Md. : 1950)
Rahman ZS,Shao WH,Khan TN,Zhen Y,Cohen PL
13-0452 was used in Flow cytometry/Cell sorting to demonstrate a critical role for Mer in GC apoptotic cell clearance by TBMΦs.
Mon Nov 15 00:00:00 EST 2010
Mucosal addressin cell-adhesion molecule-1 controls plasma-cell migration and function in the small intestine of mice.
Gastroenterology
Schippers A,Leuker C,Pabst O,Kochut A,Prochnow B,Gruber AD,Leung E,Krissansen GW,Wagner N,Müller W
13-0452 was used in Flow cytometry/Cell sorting to elucidate the in vivo role of the mucosal addressin cell-adhesion molecule-1 in B-cell migration.
Tue Sep 01 00:00:00 EDT 2009
Enhanced development of CD4+ gammadelta T cells in the absence of Itk results in elevated IgE production.
Blood
Qi Q,Xia M,Hu J,Hicks E,Iyer A,Xiong N,August A
13-0452 was used in Flow cytometry/Cell sorting to investigate the effect of Itk on T cell populations, showing that development of CD4+ gammadelta T cells is enhanced and IgE production is elevated in the absence of Itk.
Thu Jul 16 00:00:00 EDT 2009
A critical role of TAK1 in B-cell receptor-mediated nuclear factor kappaB activation.
Blood
Schuman J,Chen Y,Podd A,Yu M,Liu HH,Wen R,Chen ZJ,Wang D
Published figure using CD45R (B220) monoclonal antibody (Product # 13-0452-82) in Flow Cytometry
Thu May 07 00:00:00 EDT 2009
The transcription factors STAT5A/B regulate GM-CSF-mediated granulopoiesis.
Blood
Kimura A,Rieger MA,Simone JM,Chen W,Wickre MC,Zhu BM,Hoppe PS,O'Shea JJ,Schroeder T,Hennighausen L
13-0452 was used in Flow cytometry/Cell sorting to assess the contribution of the downstream mediating transcription factors STAT5A/B to the development of granulocytes.
Thu Nov 19 00:00:00 EST 2009
Lymphoid-tissue-specific homing of bone-marrow-derived dendritic cells.
Blood
Creusot RJ,Yaghoubi SS,Chang P,Chia J,Contag CH,Gambhir SS,Fathman CG
13-0452 was used in Immunopurification to present extensive analysis of BM-DC homing to lymph nodes after intravenous and intraperitoneal inoculation.
Thu Jun 25 00:00:00 EDT 2009
Oncogenic Kras-induced leukemogeneis: hematopoietic stem cells as the initial target and lineage-specific progenitors as the potential targets for final leukemic transformation.
Blood
Zhang J,Wang J,Liu Y,Sidik H,Young KH,Lodish HF,Fleming MD
13-0452 was used in Flow cytometry/Cell sorting to examine the role and function of oncogenic KRAS mutations in the initiation and progression of leukaemia.
Thu Feb 05 00:00:00 EST 2009
Requirement for lymphoid tissue-inducer cells in isolated follicle formation and T cell-independent immunoglobulin A generation in the gut.
Immunity
Tsuji M,Suzuki K,Kitamura H,Maruya M,Kinoshita K,Ivanov II,Itoh K,Littman DR,Fagarasan S
13-0452 was used in Immunohistochemistry on frozen tissues to investigate the sites and mechanisms for T cell-independent IgA synthesis.
Fri Aug 15 00:00:00 EDT 2008
Requirement for lymphoid tissue-inducer cells in isolated follicle formation and T cell-independent immunoglobulin A generation in the gut.
Immunity
Tsuji M,Suzuki K,Kitamura H,Maruya M,Kinoshita K,Ivanov II,Itoh K,Littman DR,Fagarasan S
13-0452 was used in Immunohistochemistry on frozen tissues to investigate the sites and mechanisms for T cell-independent IgA synthesis.
Fri Aug 15 00:00:00 EDT 2008
Vaccinia virus infection modulates the hematopoietic cell compartments in the bone marrow.
Stem cells (Dayton, Ohio)
Singh P,Yao Y,Weliver A,Broxmeyer HE,Hong SC,Chang CH
13-0452 was used in Flow cytometry/Cell sorting to show that in vivo VV infection results in the expansion of c-Kit(hi)Sca-1+Lin- (KSL) haematopoietic stem cells.
Tue Apr 01 00:00:00 EDT 2008
E47 controls the developmental integrity and cell cycle quiescence of multipotential hematopoietic progenitors.
Journal of immunology (Baltimore, Md. : 1950)
Yang Q,Kardava L,St Leger A,Martincic K,Varnum-Finney B,Bernstein ID,Milcarek C,Borghesi L
13-0452 was used in Flow cytometry/Cell sorting to show E47 controls the developmental integrity and cell cycle quiescence of hematopoietic progenitors.
Sat Nov 01 00:00:00 EDT 2008
Evidence that CD8+ dendritic cells enable the development of gammadelta T cells that modulate airway hyperresponsiveness.
Journal of immunology (Baltimore, Md. : 1950)
Cook L,Miyahara N,Jin N,Wands JM,Taube C,Roark CL,Potter TA,Gelfand EW,O'Brien RL,Born WK
13-0452 was used in Flow cytometry/Cell sorting to study the mechanism by which dendritic cells enable the development of specific T cells that modulate airway hyperresponsiveness..
Tue Jul 01 00:00:00 EDT 2008
p27 deficiency cooperates with Bcl-2 but not Bax to promote T-cell lymphoma.
PloS one
Cheng N,van de Wetering CI,Knudson CM
Published figure using CD45R (B220) monoclonal antibody (Product # 13-0452-82) in Flow Cytometry
Wed Apr 02 00:00:00 EDT 2008
Msx2-interacting nuclear target protein (Mint) deficiency reveals negative regulation of early thymocyte differentiation by Notch/RBP-J signaling.
Proceedings of the National Academy of Sciences of the United States of America
Tsuji M,Shinkura R,Kuroda K,Yabe D,Honjo T
13-0452-82 was used in Flow Cytometry to o investigate where and how Notch regulates early T cell differentiation by using specific up-regulation of Notch signaling by Mint knockout.
Tue Jan 30 00:00:00 EST 2007
Immature hematopoietic cells display selective requirements for adhesion- and degranulation-promoting adaptor protein in development and homeostatsis.
European journal of immunology
Dluzniewska J,Zou L,Harmon IR,Ellingson MT,Peterson EJ
13-0452-82 was used in Flow Cytometry to highlight the dynamic regulation of ADAP during T cell maturation and document expression patterns that suggest a possible role for ADAP in development of non-T hematopoietic lineages.
Thu Nov 01 00:00:00 EDT 2007
Phospholipase Cgamma2 contributes to light-chain gene activation and receptor editing.
Molecular and cellular biology
Bai L,Chen Y,He Y,Dai X,Lin X,Wen R,Wang D
Published figure using CD45R (B220) monoclonal antibody (Product # 13-0452-82) in Flow Cytometry
Sat Sep 01 00:00:00 EDT 2007
Essential role of phospholipase C gamma 2 in early B-cell development and Myc-mediated lymphomagenesis.
Molecular and cellular biology
Wen R,Chen Y,Bai L,Fu G,Schuman J,Dai X,Zeng H,Yang C,Stephan RP,Cleveland JL,Wang D
Published figure using CD45R (B220) monoclonal antibody (Product # 13-0452-82) in Flow Cytometry
Fri Dec 01 00:00:00 EST 2006
Basophils play a critical role in the development of IgE-mediated chronic allergic inflammation independently of T cells and mast cells.
Immunity
Mukai K,Matsuoka K,Taya C,Suzuki H,Yokozeki H,Nishioka K,Hirokawa K,Etori M,Yamashita M,Kubota T,Minegishi Y,Yonekawa H,Karasuyama H
13-0452 was used in Flow cytometry/Cell sorting to reveal a novel basophil-induced mechanism of development of chronic allergic inflammation.
Mon Aug 01 00:00:00 EDT 2005
A role for brain-derived neurotrophic factor in B cell development.
Journal of neuroimmunology
Schuhmann B,Dietrich A,Sel S,Hahn C,Klingenspor M,Lommatzsch M,Gudermann T,Braun A,Renz H,Nockher WA
Wed Jun 01 00:00:00 EDT 2005
Impaired immune responses and B-cell proliferation in mice lacking the Id3 gene.
Molecular and cellular biology
Pan L,Sato S,Frederick JP,Sun XH,Zhuang Y
Published figure using CD45R (B220) monoclonal antibody (Product # 13-0452-82) in Flow Cytometry
Wed Sep 01 00:00:00 EDT 1999
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-RA3-6B2-RE-AV-20170920122035.jpg?time=20220826?time=20220826 "CD45R (B220) Antibody (13-0452-82)")
