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Invitrogen

CD49e (Integrin alpha 5) Recombinant Rabbit Monoclonal Antibody (0S9S6)

查看其他28个CD49e (Integrin alpha 5)抗体

说明书

实验方案

技术支持

货号 MA5-55213

暂无报价

100 µL

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说明书

实验方案

技术支持

抗体检测数据 (2)

Application

CD49e (Integrin alpha 5) Antibody in Western Blot (WB)

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CD49e (Integrin alpha 5) Antibody (MA5-55213) in WB

Western blot analysis of lysates from wild type (WT) and Integrin alpha 5 (ITGA5/CD49e) knockdown (KD) HeLa cells, using CD49e (Integrin alpha 5) Recombinant Monoclonal Antibody (Product # MA5-55213) at 1:1,000 dilution followed by a HRP-conjugated Goat anti-Rabbit IgG (H+L) secondary antibody at 1:10,000 dilution. Lysates/proteins: 25 μg per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL... View More

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产品信息

MA5-55213

应用

建议稀释比

已发表文章

免疫印迹 (WB)

1:500-1:1,000

酶联免疫吸附实验 (ELISA)

1 µg/mL

产品规格

种属反应

Human

宿主/亚型

Rabbit / IgG

Expression System

HEK293 cells

分类

Recombinant Monoclonal

类型

Antibody

克隆号

0S9S6

抗原

Recombinant fusion protein containing a sequence corresponding to amino acids 42-995 of human Integrin alpha 5 (ITGA5/CD49e).

查看免疫原

偶联物

Unconjugated

形式

Liquid

浓度

0.29 mg/mL

纯化类型

Protein A

保存液

PBS, pH 7.3, with 50% glycerol, 0.05% BSA

内含物

0.05% ProClin 300

保存条件

-20° C, Avoid Freeze/Thaw Cycles

产品详细信息

Immunogen Sequence: FNLDAEAPAV LSGPPGSFFG FSVEFYRPGT DGVSVLVGAP KANTSQPGVL QGGAVYLCPW GASPTQCTPI EFDSKGSRLL ESSLSSSEGE EPVEYKSLQW FGATVRAHGS SILACAPLYS WRTEKEPLSD PVGTCYLSTD NFTRILEYAP CRSDFSWAAG QGYCQGGFSA EFTKTGRVVL GGPGSYFWQG QILSATQEQI AESYYPEYLI NLVQGQLQTR QASSIYDDSY LGYSVAVGEF SGDDTEDFVA GVPKGNLTYG YVTILNGSDI RSLYNFSGEQ MASYFGYAVA ATDVNGDGLD DLLVGAPLLM DRTPDGRPQE VGRVYVYLQH PAGIEPTPTL TLTGHDEFGR FGSSLTPLGD LDQDGYNDVA IGAPFGGETQ QGVVFVFPGG PGGLGSKPSQ VLQPLWAASH TPDFFGSALR GGRDLDGNGY PDLIVGSFGV DKAVVYRGRP IVSASASLTI FPAMFNPEER SCSLEGNPVA CINLSFCLNA SGKHVADSIG FTVELQLDWQ KQKGGVRRAL FLASRQATLT QTLLIQNGAR EDCREMKIYL RNESEFRDKL SPIHIALNFS LDPQAPVDSH GLRPALHYQS KSRIEDKAQI LLDCGEDNIC VPDLQLEVFG EQNHVYLGDK NALNLTFHAQ NVGEGGAYEA ELRVTAPPEA EYSGLVRHPG NFSSLSCDYF AVNQSRLLVC DLGNPMKAGA SLWGGLRFTV PHLRDTKKTI QFDFQILSKN LNNSQSDVVS FRLSVEAQAQ VTLNGVSKPE AVLFPVSDWH PRDQPQKEED LGPAVHHVYE LINQGPSSIS QGVLELSCPQ ALEGQQLLYV TRVTGLNCTT NHPINPKGLE LDPEGSLHHQ QKREAPSRSS ASSGPQILKC PEAECFRLRC ELGPLHQQES QSLQLHFRVW AKTFLQREHQ PFSLQCEAVY KALKMPYRIL PRQLPQKERQ VATAVQWTKA EGSY

靶标信息

The product of this gene belongs to the integrin alpha chain family. Integrins are heterodimeric integral membrane proteins composed of an alpha chain and a beta chain. This gene encodes the integrin alpha 5 chain. Alpha chain 5 undergoes post-translational cleavage in the extracellular domain to yield disulfide-linked light and heavy chains that join with beta 1 to form a fibronectin receptor. In addition to adhesion, integrins are known to participate in cell-surface mediated signalling.

仅用于科研。不用于诊断过程。未经明确授权不得转售。

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引用该产品

生物信息学

蛋白别名: CD49 antigen-like family member E; CD49e; Fibronectin receptor subunit alpha; fibronectin receptor, alpha polypeptide; fibronectin receptor, alpha subunit; integrin alpha 5; Integrin alpha-5; Integrin alpha-F; integrin, alpha 5 (fibronectin receptor, alpha polypeptide); very late activation protein 5, alpha subunit; VLA-5

基因别名: CD49e; FNRA; ITGA5; VLA-5; VLA5A

UniProt ID: (Human) P08648

Entrez Gene ID: (Human) 3678

功能

virus receptor activity epidermal growth factor receptor binding platelet-derived growth factor receptor binding integrin binding protein binding vascular endothelial growth factor receptor 2 binding metal ion binding integrin

参与通路

angiogenesis cell-substrate junction assembly cell adhesion heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules leukocyte cell-cell adhesion integrin-mediated signaling pathway memory positive regulation of cell-substrate adhesion extracellular matrix organization positive regulation of cell migration positive regulation of vascular endothelial growth factor receptor signaling pathway cell-substrate adhesion cell-cell adhesion mediated by integrin heterotypic cell-cell adhesion wound healing, spreading of epidermal cells endodermal cell differentiation viral entry into host cell positive regulation of peptidyl-tyrosine phosphorylation leukocyte migration positive regulation of sprouting angiogenesis negative regulation of anoikis