Invitrogen

CD57 Monoclonal Antibody (TB01)

产品信息

MA5-16948

应用

建议稀释比

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免疫组化 (IHC)

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免疫组化（石蜡） (IHC (P))

1:10-1:50

免疫组化（冰冻） (IHC (F))

1:10-1:100

流式细胞分析 (Flow)

1:50-1:100

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其他PubMed (Misc)

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产品规格

种属反应

Human

已发表种属

Human

宿主/亚型

Mouse / IgM

分类

Monoclonal

类型

Antibody

克隆号

TB01

抗原

Human neuroblastoma cells

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偶联物

Unconjugated Unconjugated Unconjugated

形式

Liquid

浓度

1 mg/mL

纯化类型

Ion-exchange chromatography

保存液

PBS

内含物

0.09% sodium azide

保存条件

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

运输条件

Ambient (domestic); Wet ice (international)

RRID

AB_2538423

产品详细信息

For FACS analysis, use 10 µL of the suggested working dilution to label 1x10^6 cells in 100 µL. A suggested positive control for immunohistochemical applications is human tonsil. This product does not require antigen retrieval using heat treatment prior to staining of paraffin sections but sodium citrate buffer may enhance staining.

靶标信息

CD57, also known as HNK-1 and Leu-7, is an oligosaccharide antigenic determinant present on a variety of polypeptides, lipids, and chondroitin sulphate proteoglycans. Its function is poorly understood. CD57 is expressed on a subset of natural killer (NK) cells and NK T cells.

仅用于科研。不用于诊断过程。未经明确授权不得转售。

Product References

Exploration of T-Cell Diversity Using Mass Cytometry.

Methods in molecular biology (Clifton, N.J.)

O'Boyle KC,Ohtani T,Manne S,Bengsch B,Henrickson SE,Wherry EJ,Alanio C

MA5-16948 was used in Miscellaneous, Flow Cytometry, Immunohistochemistry (Frozen), Immunohistochemistry (Paraffin) to provide R scripts that contain a detailed workflow for initial evaluation of high-dimensional data generated from cohorts of patients.

Tue Jan 26 00:00:00 EST 2021

Th1 but not Th17 cells predominate in the joints of patients with rheumatoid arthritis.

Annals of the rheumatic diseases

Yamada H,Nakashima Y,Okazaki K,Mawatari T,Fukushi JI,Kaibara N,Hori A,Iwamoto Y,Yoshikai Y

MA5-16948 was used in flow cytometry to quantify the prevalence of Th1 and Th17 cells in the joints of rheumatoid arthritis patients

Mon Sep 01 00:00:00 EDT 2008

Unique phenotype of human uterine NK cells and their regulation by endogenous TGF-beta.

Journal of leukocyte biology

Eriksson M,Meadows SK,Wira CR,Sentman CL

MA5-16948 was used in immunohistochemistry to assess the expression of NK cell receptors and cytokines in the human endometrium

Wed Sep 01 00:00:00 EDT 2004

Tropism of varicella-zoster virus for human tonsillar CD4(+) T lymphocytes that express activation, memory, and skin homing markers.

Journal of virology

Ku CC,Padilla JA,Grose C,Butcher EC,Arvin AM

MA5-16948 was used in flow cytometry to report that Varicella-zoster virus infects human tonsillar CD4(+) T cells.

Fri Nov 01 00:00:00 EST 2002

生物信息学

蛋白别名: Beta-1,3-glucuronyltransferase 1; Galactosylgalactosylxylosylprotein 3-beta-glucuronosyltransferase 1; GlcAT-P; GlcUAT-P; Glucuronosyltransferase P; HNK-1; Leu-7; LEU7 antigen; UDP-GlcUA:glycoprotein beta-1,3-glucuronyltransferase

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基因别名: B3GAT1; CD57; GLCATP; GLCUATP; HNK1; LEU7; NK-1; NK1

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UniProt ID: (Human) Q9P2W7

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Entrez Gene ID: (Human) 27087

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功能

galactosylgalactosylxylosylprotein 3-beta-glucuronosyltransferase activity metal ion binding glycosyltransferase

参与通路

carbohydrate metabolic process protein glycosylation glycosaminoglycan metabolic process chondroitin sulfate metabolic process chondroitin sulfate proteoglycan biosynthetic process