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Recommended positive controls: A431, H1299, HeLa, HepG2.
Predicted reactivity: Chicken (88%), Bovine (92%).
Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.
CDK3/CyclinE1is a member of the cyclin-dependent protein kinase family and promotes entry into S phase, in part by activating members of the E2F family of transcription factors. CDK3 can also associate with cyclin C and phosphorylates the retinoblastoma 1 protein to promote exit from G0. The CDK3 gene has been mapped to chromosomal location of 17q22-qter, telomeric to the BRCA1 gene by somatic cell hybrids analysis. The presence of a single point mutation in the CDK3 gene from several Mus musculus strains commonly used in the laboratory has been reported.
⚠WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm. For more information go to www.P65Warnings.ca.gov.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: Cell division protein kinase 3; Cyclin-dependent kinase 3
基因别名: CDK3; CDKN3
UniProt ID: (Human) Q00526
Entrez Gene ID: (Human) 1018