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产品信息
A304-432A-T
产品规格
种属反应
Human
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
Between 2775 and 2825
偶联物
形式
Liquid
浓度
1 mg/mL
纯化类型
Antigen affinity chromatography
保存液
TBS, pH 7.0 to 8.0
内含物
0.09% sodium azide
保存条件
4° C
运输条件
Wet ice
产品详细信息
The recommended shelf life for this product is 1 year from date of receipt.
靶标信息
CELSR1 is a member of the flamingo subfamily, part of the cadherin superfamily. The flamingo subfamily consists of nonclassic type cadherins; a subpopulation that does not interact with catenins. The flamingo cadherins are located at the plasma membrane and have nine cadherin domains, seven epidermal growth factor like repeats and two laminin A G type repeats in their ectodomain. They also have seven transmembrane domains, a characteristic unique to this subfamily. It is postulated that these proteins are receptors involved in contact mediated communication, with cadherin domains acting as homophilic binding regions and the EGF like domains involved in cell adhesion and receptor ligand interactions. This particular member is a developmentally regulated, neural specific gene which plays an unspecified role in early embryogenesis.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: adhesion G protein-coupled receptor C1; Cadherin EGF LAG seven-pass G-type receptor 1; Cadherin family member 9; cadherin, EGF LAG seven-pass G-type receptor 1 (flamingo homolog, Drosophila); Flamingo homolog 2; hFmi2; protocadherin flamingo 2
基因别名: ADGRC1; CDHF9; CELSR1; FMI2; HFMI2; ME2
UniProt ID: (Human) Q9NYQ6
Entrez Gene ID: (Human) 9620
establishment of planar polarity
neuron migration
neural tube closure
hair follicle development
homophilic cell adhesion via plasma membrane adhesion molecules
G-protein coupled receptor signaling pathway
Rho protein signal transduction
central nervous system development
locomotory behavior
anterior/posterior pattern specification
regulation of actin cytoskeleton organization
wound healing
establishment of planar polarity of embryonic epithelium
inner ear morphogenesis
apical protein localization
establishment of body hair planar orientation
Wnt signaling pathway, planar cell polarity pathway
orthogonal dichotomous subdivision of terminal units involved in lung branching morphogenesis
planar dichotomous subdivision of terminal units involved in lung branching morphogenesis
lateral sprouting involved in lung morphogenesis
planar cell polarity pathway involved in neural tube closure
protein localization involved in establishment of planar polarity
