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产品信息
PA5-57687
产品规格
种属反应
Human
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
偶联物
形式
Liquid
浓度
0.2 mg/mL
纯化类型
Antigen affinity chromatography
保存液
PBS, pH 7.2, with 40% glycerol
内含物
0.02% sodium azide
保存条件
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
运输条件
Wet ice
RRID
AB_2639649
产品详细信息
Immunogen sequence: NMKHLLELNK LIMKSQQESW DLEEKLLDIR KKRLQLKQAS ESKLLEIQTE KNKQKIDLDS MENSERIKII RQNLQMEI
Highest antigen sequence identity to the following orthologs: Mouse - 73%, Rat - 71%.
靶标信息
Centromere and kinetochore proteins play a critical role in centromere structure, kinetochore formation, and sister chromatid separation. The protein encoded by this gene colocalizes with inner kinetochore plate proteins CENP-A and CENP-C in both interphase and metaphase. It localizes outside of centromeric heterochromatin, where CENP-B is localized, and inside the kinetochore corona, where CENP-E is localized during prometaphase. It is thought that this protein can bind to itself, as well as to CENP-A, CENP-B or CENP-C. Multimers of the protein localize constitutively to the inner kinetochore plate and play an important role in the organization and function of the active centromere-kinetochore complex.
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生物信息学
蛋白别名: CENP-H; CENPH; Centromere protein H; Interphase centromere complex protein 35; kinetochore protein CENP-H
基因别名: CENPH; ICEN35
UniProt ID: (Human) Q9H3R5
Entrez Gene ID: (Human) 64946
